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Montana State University offers 6 new biomedical technologies for licensing
Date:8/18/2010

e immune system, its potential for low toxicity, and that it is a well-studied compound. A patent is pending and a publication is available. The research is ongoing.

The third technology is a suite of naturally derived, low to non-toxic peptides showing promise as antifungals against a broad range of fungal and yeast infections. A peptide is made of one or more amino acids linked together. Amino acids are the building blocks of proteins.

Yeast can cause extremely unpleasant infections in the mouth, vagina, skin, stomach and urinary tract. These infections are difficult to treat and can be life threatening, particularly in people whose immune system is compromised from HIV or other diseases.

Current treatments are limited in their effectiveness because of their toxicity and because they do not necessarily kill the offending organism. MSU's research has discovered a suite of peptides that can be effective at low doses in completely killing a range of yeast and fungal infections.

These peptides have potential in products such as an oral rinse to treat thrush, topical cream for vaginitis, or antifungal coatings for medical implants. Additionally, these compounds may be useful for treating candidiasis in HIV or cancer patients with weak immune systems. Patents have been issued on the technology.

The fourth technology is an inexpensive way to dramatically improve mass spectrometry, an analytical technique used by scientists worldwide.

Mass spectrometry is a mainstay for the identification and characterization of molecules in everything from crude oil to biomedical compounds. Essentially, a mass spectrometer is a scale that weighs molecules. Knowing a molecule's weight is important in identifying it.

One widespread use of mass spectrometers devices that can be as big as a chest freezer is in helping scientists identify proteins, determine what they're made of, and how they're put together by revealing thei
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Contact: Evelyn Boswell
evelynb@montana.edu
406-994-5135
Montana State University
Source:Eurekalert

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