Navigation Links
Molecule identified that increases survival of stomach cancer patients
Date:9/14/2010

"The high presence of microRNA 451 enhances the response to treatment with chemo-radiotherapy and increases the survival of patients with stomach cancer", explained Dr. Jess Garca-Foncillas, chief researcher of the Pharmacogenomics Laboratory at the Applied Medical Research Centre (CIMA) and Director of Oncology at the University Hospital of Navarra. This was one of the results presented at the IV Congress of the Spanish Society for Pharmacogenetics and Pharmacogenomic, recently held at CIMA.

Pharmacogenetics studies the genetic bases determining the response of an individual to treatment, as well as possible toxic reactions; pharmacogenomics analyses the molecular and biological mechanisms involved in a disease in order to develop new medicines. "We know that variations in small molecules (microRNAs) give rise to different responses to the same pharmaceutical drug. In this line, a number of approaches are being made in clinical practice, such as the study of mutations of the K-RAS gene in cancer of the colon or of the EGFR in lung cancer, and which enable directing individualised treatment for each patient".

The study presented at this scientific meeting analysed the role of microRNA 451 in stomach cancer, "Patients with a high expression of this molecule show greater survival rates, and so could be a biomarker for treatment response". The CIMA researchers are also taking part in other trials, such as studies with the 192 and 215 microRNAs, which influence the response to pharmaceutical drugs against cancer of the colon, at the preclinical phase.

Psychiatric and cardiovascular diseases

Besides its application in cancer, pharmacogenetics is demonstrating its efficacy in other disciplines such as psychiatry. So today, more individualised treatment can be determined for psychotic disorders and epilepsy for each patient.

Another field that is growing fast is that involving the treatment of cardiovascular diseases. "On
'/>"/>

Contact: Oihane Lakar
o.lakar@elhuyar.com
0034-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2

Related biology news :

1. Scientists identify molecules involved in touch and other mechanically activated systems
2. Juelich researchers take a look inside molecules
3. Molecules delivering drugs as they walk
4. One molecule, many more insulin-producing cells to treat diabetes, says Pitt team
5. Nanoblasts from laser-activated nanoparticles move molecules, proteins and DNA into cells
6. Correcting a trick of the light brings molecules into view
7. Molecules typically found in blue jean and ink dyes may lead to more efficient solar cells
8. Stretching molecules yields new understanding of electricity
9. Single-molecule manipulation for the masses
10. Scripps research scientists determine structure of immune molecule that counteracts HIV strains
11. New bacterial signaling molecule could lead to improved vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/10/2015)... 2015 Fingerprint Cards (FPC) has received ... from the distributor World Peace Industrial Group (WPI), part of ... Asia . Deliveries are planned to take place ... smartphone manufacturers in China . The order ... guidance of + 1 000 MSEK for 2015.   ...
(Date:4/27/2015)... April 27, 2015  For more than four decades, ... has been the premier worldwide event for the unmanned ... a must-attend event for any local, national, or trade ... emerging commercial markets and current applications of unmanned technologies. ... this projected $48 billion industry, and how it will ...
(Date:4/20/2015)... 20, 2015 The announcement comes ... Glenbeigh Records Management (GRM), Ireland,s foremost ... Bank. Having built up an impressive track record of clients ... player within the records management sector in Dubai ... is GCC staffbase and employ a further eight staff members ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... Fat removed from the lower abdomen and inner thigh ... stem cells, with higher stem cell concentrations than other areas ... Plastic and Reconstructive Surgery , the official medical journal of ... first study of its kind to examine whether fat tissues ...
... topics include confirmation that East Java,s "Lusi" mud volcano was ... well; evidence of the oldest human presence yet discovered along ... measurements that show why no large earthquakes occur in the ... the impact of Glen Canyon dam in Grand Canyon on ...
... for the Olympic Games, Cornell researcher Max Zhang has his ... air that millions breathe every day, and that many more ... summer. The assistant professor in Cornell,s Sibley School of ... the air quality before, during and after the Olympic Games, ...
Cached Biology News:Want a reason to love your lower belly fat? It's rich in stem cells 2August 2008 Geology and GSA Today media highlights 2August 2008 Geology and GSA Today media highlights 3August 2008 Geology and GSA Today media highlights 4August 2008 Geology and GSA Today media highlights 5August 2008 Geology and GSA Today media highlights 6August 2008 Geology and GSA Today media highlights 7August 2008 Geology and GSA Today media highlights 8August 2008 Geology and GSA Today media highlights 9August 2008 Geology and GSA Today media highlights 10August 2008 Geology and GSA Today media highlights 11August 2008 Geology and GSA Today media highlights 12During Olympics, Cornell's Max Zhang studies air-quality in Beijing 2During Olympics, Cornell's Max Zhang studies air-quality in Beijing 3
(Date:5/28/2015)... , May 27, 2015 Research and Markets( ... "Animal Genetics Market by Products, by Testing services - ... The global animal genetics market is estimated ... grow at a CAGR of 8-9% during the forecast ... is mainly driven by increasing animal protein consumption, increasing ...
(Date:5/28/2015)... 2015 Natera, Inc., a leader in ... in Ultrasound in Obstetrics & Gynecology ... prenatal test (NIPT) can identify a complete molar ... A study based upon data collected in the ... about 1 in 1,000 pregnancies, although other studies ...
(Date:5/28/2015)... Fla. , May 28, 2015 ... the anti-cancer potential of its growth hormone-releasing hormone (GHRH) ... at the 2015 ASCO Annual Meeting. The data show ... for Biscayne,s anti-cancer GHRH blockers, is present on many ... These findings suggest that GHRH antagonists could have broad ...
(Date:5/28/2015)... 2015 Whitehouse Laboratories is excited to ... term partnership with PTI Inspection Systems. Whitehouse Labs and ... with custom-tailored method development and validation programs using ... The agreement includes a more formal program that facilitates ... lines. This enables a more effective team approach, especially ...
Breaking Biology Technology:Global Animal Genetics (Canine, Equine, Poultry, Porcine, Bovine, and Genetic Material) Market 2015 - Global Forecast to 2020 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 3Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 2Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 3Whitehouse Labs Renews & Enhances Partnership with PTI Inspection Systems 2Whitehouse Labs Renews & Enhances Partnership with PTI Inspection Systems 3
... at the National Institute of Standards and Technology (NIST) ... viscosity measurementscritical data for a wide variety of fields ... as small as a few nanoliters. Currently a table-top ... tool for biotechnologists studying minute quantities of complex materials ...
... Mr. Robert Nealon reports: IGEN Networks Corp. ... Standard and Poor,s ("S&P") has approved IGEN for their ... Records is considered the premier source for information on ... professionals. As part of the approval, IGEN,s corporate profile ...
... of Services in Neuronal Research Using Human iPS... -- YOKOHAMA, Japan, September 1, 2010 ... ... --> ... var s = ,; var first_result; // Results are keyed by longUrl, so we need to grab ...
Cached Biology Technology:Micro rheometer is latest Lab On a Chip device 2IGEN Networks Corp. obtains Blue Sky Statutory Compliance in 38 States with Approval of Standard & Poor's 2ReproCELL Announces New Line of Services in Neuronal Research Using Human iPS Cells 2ReproCELL Announces New Line of Services in Neuronal Research Using Human iPS Cells 3ReproCELL Announces New Line of Services in Neuronal Research Using Human iPS Cells 4ReproCELL Announces New Line of Services in Neuronal Research Using Human iPS Cells 5ReproCELL Announces New Line of Services in Neuronal Research Using Human iPS Cells 6
... ,This solution greatly enhances antigen-antibody reactions, yielding ... with conventional methods. ,Two kinds of solution ... which can suppress the background and increase ... ,It is applicable to various assay system ...
Mouse Anti-Human Killer Cell Immunoglobulin-like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2 (KIR2DL3 Monoclonal Antibody Family: Immunoglobulin Sub-Family: not assigned-Immunogl...
pH-dependent fluorescence; Maximum intensity observed in basic solutions....
Mouse anti human pro-Relaxin-2...
Biology Products: