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Molecular medicine could avert predicted catastrophic vision loss in the aged
Date:1/10/2011

the antioxidant cocktail, which suggests cause and effect," he says.

Dr. Richer showed an audience of stunned researchers the first photographic slides of their kind old, damaged retinas that are pocked with aging spots, hemorrhages and poor circulation, becoming more youthful and functional over a relatively short period of time. "We simply need to move to larger human trials where we can determine the reliability and safety of this approach. This can be accomplished within a year, we do not need to wait a decade to conclusively validate this approach," he says.

"The small molecules in the nutriceutical cocktail we used, such as resveratrol, quercetin, rice bran phytate, as provided in commercially-available product called Longevinex, appear to work synergistically and more powerfully in animal studies of heart disease, which is why it was chosen for compassionate use in these individual cases of age-related eye disease," says Dr. Richer.

These cases were deemed unsuitable by a retinal specialist for medical therapy, which consists of injecting an anti-growth factor drug directly into the eye. "There were no remaining options for these patients," says Dr. Richer.

The possibility of using an oral pill rather than injections directly into the eyes is likely to be more welcomed by patients. Such a pill would cost less than a dollar a day. Injectable drug therapy costs around $1000 per injection and six or more injections are often required.

Dr. Richer calls attention to the fact that many senior Americans remain active and drive automobiles but don't fully recognize their vision is fading, and they are developing blind spots, especially if these changes occur in one eye only. Age-related visual decline represents a major road hazard he emphasizes.

"We have growing evidence that molecular medicine can turn mortal heart attacks into non-mortal events and accelerate healing of a damaged heart, and now w
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Contact: Stuart Richer, O.D., Ph.D.
Stuart.Richer1@va.gov
847-409-4131
Resveratrol Partners LLC, dba LONGEVINEX
Source:Eurekalert

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