Navigation Links
Molecular mechanism contributing to neuronal circuit formation found
Date:3/7/2011

During embryonic development, sensory and motor fibers interact to form nerves in the limbs. The research team led by Dr. Andrea Huber Brsamle of the Institute of Developmental Genetics of Helmholtz Zentrum Mnchen has now elucidated how this interaction functions at the molecular level: The cell surface receptor neuropilin-1 is present in both sensory and motor nerve fibers and controls their interaction in order to correctly regulate growth.

"We observed that motor and sensory axons were both able to guide and lead the formation of the spinal nerves of the arms and legs," said Rosa-Eva Httl and Heidi Sllner, lead authors of the study and doctoral students in Dr. Andrea Huber Brsamle's research group. This finding surprised the authors because it had previously been assumed that the motor axons were always responsible for establishing the correct trajectories. In the same study, the researchers created a model to better elucidate structural changes in human neurodegenerative disorders and following trauma : "Our next goal," said Dr. Huber Brsamle, "is to find out to what extent neuropilin-1 also controls the formation of fiber tracts in the brain."


'/>"/>

Contact: Sven Winkler
presse@helmholtz-muenchen.de
0049-089-318-73946
Helmholtz Zentrum Mnchen - German Research Center for Environmental Health
Source:Eurekalert

Page: 1

Related biology news :

1. Combined molecular study techniques reveal more about DNA proteins
2. Fingerprints match molecular simulations with reality
3. Designing new molecular tools to study the life and death of a cancer cell
4. Molecular network influences development of chronic lymphocytic leukemia
5. Polymer membranes with molecular-sized channels that assemble themselves
6. Molecular medicine could avert predicted catastrophic vision loss in the aged
7. New book highlights the cellular and molecular determinants of brain wiring
8. Scientists discover molecular switch that contributes to cellular aging process
9. Molecular fossil
10. Association for Molecular Pathologys 16th Annual Meeting and Exhibits
11. Understanding diabetes at the molecular level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2016)... , UAE, April 20, 2016 ... be implemented as a compact web-based "all-in-one" system solution ... the biometric fingerprint reader or the door interface with ... of modern access control systems. The minimal dimensions of ... ID readers into the building installations offer considerable freedom ...
(Date:4/14/2016)... 14, 2016 BioCatch ™, ... today announced the appointment of Eyal Goldwerger ... Goldwerger,s leadership appointment comes at a time ... the deployment of its platform at several of the ... which discerns unique cognitive and physiological factors, is a ...
(Date:3/31/2016)... March 31, 2016  Genomics firm Nabsys has completed ... Barrett Bready , M.D., who returned to the ... original technical leadership team, including Chief Technology Officer, ... Development, Steve Nurnberg and Vice President of Software and ... company. Dr. Bready served as CEO of ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... ... to announce the launch of their brand, UP4™ Probiotics, into Target stores nationwide. ... years, is proud to add Target to its list of well-respected retailers. This ...
(Date:6/23/2016)... SILVER SPRING, Md. , June 23, 2016 ... evidence collected from the crime scene to track the criminal ... sick, and the U.S. Food and Drug Administration (FDA) uses ... Sound far-fetched? It,s not. ... whole genome sequencing to support investigations of foodborne illnesses. Put ...
(Date:6/23/2016)... -- The Prostate Cancer Foundation (PCF) is pleased to announce 24 new ... prostate cancer. Members of the Class of 2016 were selected from a pool ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... the launch of the Supplyframe Design Lab . Located in Pasadena, Calif., ... the future of how hardware projects are designed, built and brought to market. ...
Breaking Biology Technology: