Navigation Links
Molecular mechanism contributing to neuronal circuit formation found
Date:3/7/2011

During embryonic development, sensory and motor fibers interact to form nerves in the limbs. The research team led by Dr. Andrea Huber Brsamle of the Institute of Developmental Genetics of Helmholtz Zentrum Mnchen has now elucidated how this interaction functions at the molecular level: The cell surface receptor neuropilin-1 is present in both sensory and motor nerve fibers and controls their interaction in order to correctly regulate growth.

"We observed that motor and sensory axons were both able to guide and lead the formation of the spinal nerves of the arms and legs," said Rosa-Eva Httl and Heidi Sllner, lead authors of the study and doctoral students in Dr. Andrea Huber Brsamle's research group. This finding surprised the authors because it had previously been assumed that the motor axons were always responsible for establishing the correct trajectories. In the same study, the researchers created a model to better elucidate structural changes in human neurodegenerative disorders and following trauma : "Our next goal," said Dr. Huber Brsamle, "is to find out to what extent neuropilin-1 also controls the formation of fiber tracts in the brain."


'/>"/>

Contact: Sven Winkler
presse@helmholtz-muenchen.de
0049-089-318-73946
Helmholtz Zentrum Mnchen - German Research Center for Environmental Health
Source:Eurekalert

Page: 1

Related biology news :

1. Combined molecular study techniques reveal more about DNA proteins
2. Fingerprints match molecular simulations with reality
3. Designing new molecular tools to study the life and death of a cancer cell
4. Molecular network influences development of chronic lymphocytic leukemia
5. Polymer membranes with molecular-sized channels that assemble themselves
6. Molecular medicine could avert predicted catastrophic vision loss in the aged
7. New book highlights the cellular and molecular determinants of brain wiring
8. Scientists discover molecular switch that contributes to cellular aging process
9. Molecular fossil
10. Association for Molecular Pathologys 16th Annual Meeting and Exhibits
11. Understanding diabetes at the molecular level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/3/2017)... 2017  Data captured by IsoCode, IsoPlexis ... a statistically significant association between the potency ... and objective response of cancer patients post-treatment. ... whether cancer patients will respond to CAR-T ... as to improve both pre-infusion potency testing and ...
(Date:3/29/2017)... , March 29, 2017  higi, the health IT ... North America , today announced a ... the acquisition of EveryMove. The new investment and acquisition ... of tools to transform population health activities through the ... data. higi collects and secures data today ...
(Date:3/24/2017)... , Mar 24, 2017 Research and ... Access System Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 15.1% over the next ... This industry report analyzes the market estimates and forecasts for all ...
Breaking Biology News(10 mins):
(Date:6/23/2017)... ... June 23, 2017 , ... The Academy of Model ... University Aviation Association (UAA), the unifying voice for collegiate aviation education, are launching ... teamwork, competition, and success through a STEM-based education platform. , Much like the ...
(Date:6/22/2017)... Colorado (PRWEB) , ... June 21, 2017 , ... ... RTP regional office in North Carolina, and engages Timothy Reinhardt to manage the ... of quality leadership at Pfizer Inc, with his most recent role as the ...
(Date:6/22/2017)... Germany (PRWEB) , ... June 22, 2017 , ... ... is taking over the allergy specialists DST Diagnostische Systeme & Technologien GmbH, thereby ... all know someone who suffers from hay fever, urticaria, asthma, atopic eczema or ...
(Date:6/22/2017)... ... June 22, 2017 , ... For the months ... produced a Spotlight series on “Cell Therapy Regulation” for its regenerative ... experts on the unique regulatory challenges of stem cell medical research. , Stem ...
Breaking Biology Technology: