Navigation Links
Molecular mechanism contributing to neuronal circuit formation found
Date:3/7/2011

During embryonic development, sensory and motor fibers interact to form nerves in the limbs. The research team led by Dr. Andrea Huber Brsamle of the Institute of Developmental Genetics of Helmholtz Zentrum Mnchen has now elucidated how this interaction functions at the molecular level: The cell surface receptor neuropilin-1 is present in both sensory and motor nerve fibers and controls their interaction in order to correctly regulate growth.

"We observed that motor and sensory axons were both able to guide and lead the formation of the spinal nerves of the arms and legs," said Rosa-Eva Httl and Heidi Sllner, lead authors of the study and doctoral students in Dr. Andrea Huber Brsamle's research group. This finding surprised the authors because it had previously been assumed that the motor axons were always responsible for establishing the correct trajectories. In the same study, the researchers created a model to better elucidate structural changes in human neurodegenerative disorders and following trauma : "Our next goal," said Dr. Huber Brsamle, "is to find out to what extent neuropilin-1 also controls the formation of fiber tracts in the brain."


'/>"/>

Contact: Sven Winkler
presse@helmholtz-muenchen.de
0049-089-318-73946
Helmholtz Zentrum Mnchen - German Research Center for Environmental Health
Source:Eurekalert

Page: 1

Related biology news :

1. Combined molecular study techniques reveal more about DNA proteins
2. Fingerprints match molecular simulations with reality
3. Designing new molecular tools to study the life and death of a cancer cell
4. Molecular network influences development of chronic lymphocytic leukemia
5. Polymer membranes with molecular-sized channels that assemble themselves
6. Molecular medicine could avert predicted catastrophic vision loss in the aged
7. New book highlights the cellular and molecular determinants of brain wiring
8. Scientists discover molecular switch that contributes to cellular aging process
9. Molecular fossil
10. Association for Molecular Pathologys 16th Annual Meeting and Exhibits
11. Understanding diabetes at the molecular level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2016)... Nov. 22, 2016   MedNet Solutions , an ... spectrum of clinical research, is pleased to announce that ... Healthcare and Life Sciences Awards as "Most Outstanding ... an unprecedented year of recognition and growth for MedNet, ... 15 years. iMedNet ™ , ...
(Date:11/16/2016)... Sensory Inc ., a Silicon ... consumer electronics, and VeriTran , a technology ... today announced a global partnership that will provide ... users of mobile banking and mobile payments solutions.  ... which requires no specialized biometric scanners, yet provides ...
(Date:6/27/2016)... 27, 2016 Research and Markets has announced ... report to their offering. ... to grow at a CAGR of 12.28% during the ... on an in-depth market analysis with inputs from industry experts. The ... coming years. The report also includes a discussion of the key ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... ... December 07, 2016 , ... ... today a new service to enable rapid migration of large pathology data sets ... one of the factors limiting adoption of digital pathology. Proscia’s free massive dataset ...
(Date:12/7/2016)... Hole, Massachusetts (PRWEB) , ... December 07, 2016 , ... Kara Dwyer Dodge grew up ... Richard Dwyer, a third-generation fisherman in Scituate, Mass., found a sea turtle entangled in the ... shore, where the turtle became a minor sensation because no one could remember ever seeing ...
(Date:12/6/2016)... ... December 06, 2016 , ... ... Almac Group, the world’s largest privately-held contract pharmaceutical development and manufacturing organisation, ... a leading biopharma outsourcing company combining a leading CRO and the industry’s ...
(Date:12/6/2016)... ... December 06, 2016 , ... Superior ... IT solutions, today announced the company has successfully completed its 50th consecutive audit. ... and control systems integration services to leading companies in life sciences, food and ...
Breaking Biology Technology: