Navigation Links
Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment
Date:3/23/2009

y. If the patient has cancer, you want to pick it up. We need to have a kind of multiplex test where you can test for say10 different entities and have a greater confidence that what you are stating about the tumor is true. Our goal is to develop such a panel and research on sarcosine is a first step toward achieving this."

In his new position at MCG, he's looking to expand the number of metabolites known to be predictive of prostate and other cancers. In prostate cancer, he's beginning with follow up on other metabolites identified in the Michigan study in which researchers identified a total of six metabolites, including sarcosine, linked to increased tumor progression. A total of 89 metabolites were different in metastatic prostate cancer compared to localized disease.

He's excited about what metabolites will one day tell cancer physicians and patients but adds that they are just a piece of what our bodies can tell us about a potential cancer growing inside. Scientists also need to continue to look at genes expressed by tumors and the proteins expressed by those genes to get the bigger picture. "It's basically a systems approach you need to take," he says.

The young scientist has worked with all those pieces in his relatively short career. He started his postdoctoral fellowship at the University of Michigan in1999, when the ability to look at gene expression was new. With his mentor, Dr. Arul M. Chinnaiyan, director of Michigan Center for Translational Pathology, Pathology Research Informatics and Cancer Bioinformatics at Michigan, he helped develop the next step: the ability to look at expression of hundreds of proteins at a time, instead of a handful, an important advance in light of the fact that there are about 1 million proteins. Recently they were among the first to venture into the world of metabolites, which are made by proteins.

"Previous technology was looking at a cell from a narrow perspective and cells never act
'/>"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. New molecular regulators of hyperthyroidism and goiter
2. Carnegie Mellon scientists investigate initial molecular mechanism that triggers neuronal firing
3. UC health news: molecular pathway may predict chemotherapy effectiveness
4. New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed
5. Story ideas from Molecular & Cellular Proteomics
6. Lets talk -- new paradigms in the research of the biomolecular composition of water
7. Scientists unveil structure of molecular target of many drugs
8. Potential new therapeutic molecular target to fight cancer
9. NIH selects LIAI for major study on allergy molecular causes and possible treatments
10. Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery
11. Leading cause of death in preemies might be controlled by resetting a molecular switch
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment
(Date:3/12/2015)... -- Beta Systems today announced Fast ... (IAM) solution for a fixed price and with ... IAM package, customers benefit from the 30 years, ... implementations across different industries. The new fixed-price IAM ... necessary services and consulting. It spans the implementation ...
(Date:3/11/2015)... , March 11, 2015   The ... its platform to scientifically measure and harness music ... to real-time biometrics and objective measurements of physiology, ... music at scale in large populations. It is ... technologists and clinicians perform rigorous studies and accelerate ...
(Date:3/10/2015)... 2015   Tute Genomics , pioneer in affordable, ... next-generation sequencing company PrimBio Research Institute to ... gene panel interpretation. PrimBio, a certified Life ... current technologies to support the work of experts on ... two types of exome sequencing services: 1) Targeted Exome ...
Breaking Biology News(10 mins):Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 2Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 3PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 3
... -- Nov. 12, 2007 -- The syrupy soup of proteins, ... packed it may increase the structural content of proteins by ... Rice University and the University of Houston (UH). The study ... crowded environment inside a living cell affects protein structure. , ...
... population study of microbes in Yellowstone National Park hot ... distant pools. The result, to be published online next ... Sciences, could help to answer some fundamental questions about ... their environment. ,Researchers at Montana State University and Idaho ...
... by researchers at the University of Southern California (USC) identifies ... in the density of nucleosomes within the cells. The ... Cancer Cell, will enable researchers to explore new therapies to ... treatments for human cancers, says study lead author Peter A. ...
Cached Biology News:Proteins pack tighter in crowded native state 2Proteins pack tighter in crowded native state 3Yellowstone viruses 'jump' between hot pools 2
(Date:3/26/2015)... CINCINNATI , March 26, 2015 ... SHPG ) and Cincinnati Children,s Hospital Medical Center ... rare diseases. The goal of the collaboration is to ... diseases with high unmet medical need combining Shire,s ... expertise. As a nationally ranked hospital, Cincinnati Children,s ...
(Date:3/26/2015)... Texas (PRWEB) March 26, 2015 ReliantHeart, ... technologies, and Transonic, a supplier of precision transit-time flow ... that will greatly improve the efficiency of the ... enable LVAD patients to experience greater mobility and peace ... with the miniature flow board, will draw 1/6th of ...
(Date:3/26/2015)... 2015 WriteResult, a premier provider of ... Yale University’s School of Public Health and New Haven ... a 4 month-long project. The goal of the study ... families with free access to fresh produce and nutrition ... concerns like high blood pressure, diabetes and weight gain. ...
(Date:3/25/2015)... , March 25, 2015 /PRNewswire/ - SQI Diagnostics Inc. ... that, as a result of recent discussions with certain ... shares of the Company, after dealing with certain matters ... special meeting of shareholders on March 26, 2015 (the ... the election of directors will take place when the ...
Breaking Biology Technology:Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 3Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 4Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 5LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 3Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 2Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5
... WALTHAM, Mass., Aug. 20 Thermo Fisher,Scientific Inc. ... executive,officers, including Marijn E. Dekkers, president and chief ... and Exchange,Commission (SEC) Rule 10b5-1 covering the future ... for and sold 300,000 shares over August,15-17, 2007, ...
... Dr. Liew awarded Malaysia,s Darjah Yang Mulia Pangkuan ... GeneNews Limited (TSX: GEN),a company focused on developing ... diseases and personalized health management, today,announced that its ... awarded the Darjah Yang Mulia Pangkuan Negeri (DMPN), ...
... August 20 - Essential, Structure-Searchable ... Data to Researchers Elsevier Information Systems ... publisher of scientific, technical and medical information,is ... 2007, the CrossFire Beilstein,database will contain more ...
Cached Biology Technology:Thermo Fisher Scientific Executive Officers Adopting SEC Rule 10b5-1 Trading Programs 2GeneNews CSO Dr. CC Liew awarded state honour by the Government of Malaysia 2CrossFire Beilstein Database Exceeds Ten Million Compounds 2CrossFire Beilstein Database Exceeds Ten Million Compounds 3
anti-JNK2 Immunogen: Recombinant human JNK2 protein Accession Number: NM_002752 Quality Assurance: Routinely evaluated by immunoblot. Molecular Weight: 46 and/or 54 kDa Available ...
Gloves are 9.25 long, latex, powder free, smooth and ambidextrous....
Request Info...
... KLH-conjugated, synthetic peptide corresponding ... of human BRAF-HDAC complex protein/Lysine-specific ... Quality Assurance Routinely evaluated ... 2 years at -20°C ...
Biology Products: