Navigation Links
Molecular biology provides clues to health benefits of olive oil
Date:6/28/2010

This release is available in Spanish.

Health conscious consumers have long known that virgin olive oil is a good choice when it comes to preparing meals and dipping breads. Now, a team of researchers, including one with the Agricultural Research Service (ARS), has found that phenolic components in olive oil actually modify genes that are involved in the inflammatory response.

The researchers knew from other studies that consuming high-phenolic-content virgin olive oil reduces pro-inflammatory, pro-oxidant and pro-blood-clotting biomarkers when compared with consuming low-phenolic-content olive oil. But they wanted to know whether olive oil's beneficial effects could be the result of gene activity.

The study, published recently in Biomed Central (BMC) Genomics, was done by a multi-institute group of researchers headed by Francisco Perez-Jimenez with the University of Cordoba, Spain. Among the researchers was ARS computational biologist Laurence Parnell, with the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University in Boston, Mass.

For the study, the researchers fed 20 volunteerswho had metabolic syndromewith two virgin olive oil-based breakfasts one at a time, after a six-week "washout" period. Metabolic syndrome is a prevalent condition often characterized as having a combination of abdominal obesity, high triglycerides, high blood pressure and poor blood sugar control, all of which increase risk for heart disease and diabetes.

One of the experimental breakfasts contained virgin olive oil with high-content phenolic compounds (398 parts per million) and the other breakfast contained olive oil with low-content phenolic compounds (70 parts per million). All volunteers consumed the same low-fat, carbohydrate rich "background" diet during both study phases.

The researchers tracked the expression of more than 15,000 human genes in blood cells during the after-meal period. The results indicated that 79 genes are turned down and 19 are turned up by the high-phenolic-content olive oil. Many of those genes have been linked to obesity, high blood-fat levels, type 2 diabetes and heart disease. Importantly, several of the turned-down genes are known promoters of inflammation, so those genes may be involved in "cooling off" inflammation that often accompanies metabolic syndrome.

The researchers concluded that the results shed light on a molecular basis for reduced heart disease risk among people living in Mediterranean countries where virgin olive oil is the main source of dietary fats.


'/>"/>

Contact: Rosalie Marion Bliss
Rosalie.Bliss@ars.usda.gov
301-504-4318
United States Department of Agriculture-Research, Education, and Economics
Source:Eurekalert

Related biology news :

1. NSF grant will develop new online hub for biochemistry, molecular biology educators
2. Elsevier announces the winner of the Ahmed Zewail prize in molecular sciences
3. Molecular discovery suggests new strategy to fight cancer drug resistance
4. Genetics Society of America to host 2010 Yeast Genetics & Molecular Biology Meeting
5. Molecular methods are not sufficient in systematics and evolution
6. Team led by Scripps Research scientists discovers bodys own molecular protection against arthritis
7. Pitt pharmacologists go on a molecular fishing trip and hook prize catch
8. New tool helps scientists see molecular signals of eye disease before symptoms arise
9. Lollipops and ice fishing: Molecular rulers used to probe nanopores
10. UT Southwestern researchers identify key molecular step to fighting off viruses
11. Scientists sever molecular signals that prolific parasite uses to puppeteer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2016)... Dec. 14, 2016 "Increase in mobile transactions ... The mobile biometrics market is expected to grow from ... by 2022, at a CAGR of 29.3% between 2016 ... as the growing demand for smart devices, government initiatives, ... "Software component is expected to grow at a ...
(Date:12/8/2016)... , Dec. 8, 2016 Market Research Future published ... Market. The global Mobile Biometric Security and Service Market is expected ... to 2022. Market Highlights: ... , , Mobile Biometric ... due to the increasing need of authentication and security from unwanted ...
(Date:12/7/2016)... to a new market research report "Emotion Detection and Recognition Market by Technology ... End User, And Region - Global Forecast to 2021", published by MarketsandMarkets, the ... USD 36.07 Billion by 2021, at a Compound Annual Growth Rate (CAGR) of ... ... MarketsandMarkets Logo ...
Breaking Biology News(10 mins):
(Date:1/20/2017)... BOSTON , Jan. 20, 2017 ... acquisition of Gen9, a pioneer in the synthesis ... Gen9,s unique expertise in assembling pathway-length synthetic DNA ... speed and capacity in the construction of new ... of industries. "Gen9 was founded to ...
(Date:1/19/2017)... and HOUSTON , ... ("NX Prenatal") today announced the formation of its ... leading clinicians and industry veterans who enhance the ... as it accelerates development of its novel prenatal ... provide medical, clinical and strategic guidance for the ...
(Date:1/19/2017)... GAITHERSBURG, Md. , Jan. 19, ... Altimmune, Inc., a privately-held immunotherapeutics company targeting infectious ... agreement for the merger of PharmAthene and Altimmune ... Novartis Venture Fund, HealthCap, Truffle Capital and Redmont ... and diversified immunotherapeutics company with four clinical stage ...
(Date:1/19/2017)... ... January 19, 2017 , ... FireflySci Inc. is a go-getter type of company ... is accounted to two main factors. The first is the amazing customer service ... supplying FireflySci products all around the world. , 2016 was a tremendous sales year ...
Breaking Biology Technology: