Navigation Links
Modifications of a nanoparticle can change chemical interactions with cell membranes
Date:1/23/2013

Researchers at Syracuse University's Department of Biomedical and Chemical Engineering at L.C. Smith College of Engineering and Computer Science are studying the toxicity of commonly used nanoparticles, particles up to one million times smaller than a millimeter that could potentially penetrate and damage cell membranes.

In a recent article published along with cover art in the leading journal Langmuir entitled "Effects of nanoparticle charge and shape anisotropy on translocation through cell membranes," researchers Shikha Nangia, assistant professor of biomedical and chemical engineering (BMCE), and Radhakrishna Sureshkumar, Department Chair of BMCE and professor of physics, showed how simple shape and charge modifications of a nanoparticle can cause tremendous changes in the chemical interactions between the nanoparticle and a cell membrane.

Nanomaterials, which are currently being used as drug carriers, also pose a legitimate concern, since no universal standards exist to educate and fully protect those who handle these materials. Nanoparticles are comparable to chemicals in their potential threat because they could easily penetrate the skin or be inhaled.

"Nanotechnology has immense potential that is starting to be being realized; a comprehensive understanding of toxicity of nanoparticles will help develop better safe handling procedures in nanomanufacturing and nano-biotechnology" says Sureshkumar and Nangia, In addition, the toxicity levels of various nanoparticles can be used to our advantage in targeting cancer cells and absorbing radiation during cancer therapy. Nanotoxicity is becoming a major concern as the use of nanoparticles in imaging, therapeutics, diagnostics, catalysis, sensing and energy harvesting continues to grow dramatically.

This research project has taken place over the past year utilizing a state of the art 448 core parallel computer nicknamed "Prophet" housed in Syracuse University's Green D
'/>"/>

Contact: Ariel DuChene
adduchen@syr.edu
315-443-2546
Syracuse University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Scientists uncover mechanism by which plants inherit epigenetic modifications
2. Are silver nanoparticles harmful?
3. Hybrid copper-gold nanoparticles convert CO2
4. NIST/UMass study finds evidence nanoparticles may increase plant DNA damage
5. From pomegranate peel to nanoparticles
6. Palladium-gold nanoparticles clean TCE a billion times faster than iron filings
7. Paints and coatings containing bactericidal agent nanoparticles combat marine fouling
8. Silver nanoparticle synthesis using strawberry tree leaf
9. Oh, my stars and hexagons! DNA code shapes gold nanoparticles
10. Nanoparticles added to platelets double internal injury survival rate
11. Nanoparticles reboot blood flow in brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... in the United States, wildland managers often utilize the ... trees (ladder fuels). These cuttings and other post-logging ... danger in order to dispose of the material. To ... often cover all or part of the debris pile ... plastic, in order to keep water out. A recent ...
(Date:7/24/2014)... of the primordial soup in which life arose have been ... University of East Anglia. , Research published today in the ... plants, yeast and very likely also in animals still perform ... of life some four billion years ago. , The ... or ocean as a result of the combination of metals, ...
(Date:7/24/2014)... a new drug that successfully treated lupus in mice, a ... $250,000 grant to expand his research to a new version ... range of autoimmune diseases., Chandra Mohan, Hugh Roy and Lillie ... published a study in Arthritis Research & Therapy outlining the ... mice and reduced the number of cases of lupus-related kidney ...
Breaking Biology News(10 mins):Study gives new perspective on agricultural plastic, debris burning, and air quality 2Biomedical engineer looks at new applications for novel lupus drug 2Biomedical engineer looks at new applications for novel lupus drug 3
... A deep ocean current with a volume equivalent to 40 ... near the Kerguelen plateau, in the Indian Ocean sector of ... paper published today in Nature Geoscience , the researchers ... surface as an important pathway in a global network ...
... National Oceanography Centre in Southampton, have today set sail from ... Ocean affected by ash from the Icelandic volcano eruption to ... of the ocean the productivity of microscopic plants, called phytoplankton, ... sequester carbon dioxide from the atmosphere, is limited by the ...
... Spanish . , Two new compact oakleaf ... by Agricultural Research Service (ARS) scientists. "Ruby Slippers" ... geneticist Sandy Reed with the U.S. National Arboretum,s Floral ... The arboretum is operated by ARS, the principal intramural ...
Cached Biology News:Massive Southern Ocean current discovered 2Scientists to measure impact of volcanic ash on ocean biology 2New hydrangea cultivars for landscape gardens 2
(Date:7/24/2014)... Calif. , July 24, 2014  Now available ... to home. Rehealth Regenerative Therapies , located in ... and other physically active people a new health option: ... Regardless of age, countless patients suffer from joint ... activities, such as muscle tears, torn rotator cuff, tennis ...
(Date:7/24/2014)... Quantum computers have yet to materialise. Yet, scientists ... making such computers faster. One such approach relies ... controlled by applying an electric field. A new ... coherently coupled quantum dots (TQDs) with electrical impulses ... for example, should TQDs be used as quantum ...
(Date:7/24/2014)... 2014 Your cell phone may ... lithium-ion battery storage capacity. , New research indicates ... model created at Lawrence Livermore National Laboratory ... how carbon components will perform as electrodes. , ... urgent need for higher-performance batteries. Several key characteristics ...
(Date:7/24/2014)...  Neogen Corporation (Nasdaq: NEOG ) advised ... revenue from new rodenticide research are premature. In its ... July 22, 2014, Neogen,s CEO commented about several new ... "It was my intent Tuesday at our conference ... new type of rodenticide, but certainly not to give ...
Breaking Biology Technology:Stem Cells In Sports Injuries, Joints And Muscular Pain 2Stem Cells In Sports Injuries, Joints And Muscular Pain 3Getting More Life out of Lithium-ion Batteries 2Neogen comments on SenesTech 2
... Santini, Jr., PhD, CEO of,MicroCHIPS, Inc., is named ... the,2008 class of "young geniuses shaping the future ... Dr. Santini is the only honoree who is ... commercial venture.,His company, MicroCHIPS, is pioneering intelligent medical ...
... Joins as Associate Director, SAN FRANCISCO, ... today announced that it has launched Invigorate,Communications, ... serving,the diverse communications needs of leading biopharmaceutical, ... interested in,building health-based brands. Invigorate currently provides ...
... 14 Imaging,Diagnostic Systems, Inc., (OTC Bulletin Board: ... systems, announced today that its,distributor, Laszlo Meszaros of ... Mammography (CTLM(R)) system for Budapest, Hungary., (Logo: ... will be installed at the new MeDoc HealthCare ...
Cached Biology Technology:MicroCHIPS CEO Named in Popular Science's 'Seventh Annual Brilliant 10' 2WeissComm Launches Invigorate Communications to Help Companies Build Successful Health-Based Brands 2Imaging Diagnostic Systems Sells Its CT Laser Mammography System to Budapest, Hungary 2
Methylation analysis of gene promoters using bilsulfite treatment of DNA and comparative DNA sequence analysis. Probe design and PCR included....
... Agencourt offers quick turnaround sequencing of individual ... and high copy plasmids. Agencourt's world-class, high ... Phred20 bases per day. The key ... service are 24 48 hour sample ...
A component of the Acridinium protein labeling kit....
... Life Sciences can provide custom microplate coating using advanced automated ... variety of plate formats. We can also accommodate virtually any ... of 0.5-320 L):, , ... 96 well microplate, 384 well ...
Biology Products: