Navigation Links
Moderate doses of radiation therapy to unaffected breast may prevent second breast cancers
Date:1/23/2014

NEW YORK, NY (January 23, 2014) Survivors of breast cancer have a one in six chance of developing breast cancer in the other breast. But a study conducted in mice suggests that survivors can dramatically reduce that risk through treatment with moderate doses of radiation to the unaffected breast at the same time that they receive radiation therapy to their affected breast. The treatment, if it works as well in humans as in mice, could prevent tens of thousands of second breast cancers. The study, conducted by researchers at Columbia University Medical Center (CUMC), was published on December 20 in the online journal PLOS ONE.

"Over the past decades, we've had great success in treating breast cancer, and the 15-year survival rate is now 77 percent," said study leader David J. Brenner, PhD, director of CUMC's Center for Radiological Research and the Higgins Professor of Radiation Biophysics. "Unfortunately, breast cancer survivors have a several times higher risk of developing cancer in their other breast, compared with healthy women of the same age."

"While drugs such as tamoxifen and aromatase inhibitors can reduce the risk somewhat, at least for women with estrogen receptor-positive tumors, the long-term risks of a second breast cancer in the unaffected breast remain high. Because of these risks, approximately 10 to 20 percent of breast cancer survivors in the U.S. undergo prophylactic mastectomy of their other breast," said Dr. Brenner.

The idea for prophylactic mammary irradiation (PMI) of the unaffected breast stems from an earlier study of standard whole-breast irradiation after lumpectomy. In that study, Dr. Brenner found that radiation is highly effective at killing premalignant cells, not only in the quadrant of the breast where the primary tumor was located, but also in the other three quadrants, where premalignant cells are generally considered to be unrelated to the primary tumor. "So, we thought, why can't we
'/>"/>

Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Study: Moderate alcohol consumption boosts bodys immune system
2. New study suggests coral reefs may be able to adapt to moderate climate change
3. Moderate exercise not only treats, but prevents depression
4. Latest research suggests moderate coffee consumption is not associated with increased CVD risk
5. Moderate exercising encourages a healthier lifestyle
6. UEA research shows moderate exercise could be good for your tendons
7. Experts find epigenetic changes moderate reality distortion in schizophrenia patients
8. Cells must use their brakes moderately for effective speed control
9. CNBC Senior Analyst Ron Insana Moderates Discussion On Biotech Seeds At The Food Dialogues(SM): Chicago
10. Researchers issue forecast for moderate New England red tide in 2013
11. Moderate drinking decreases number of new brain cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Moderate doses of radiation therapy to unaffected breast may prevent second breast cancers
(Date:6/15/2015)... June 15, 2015 A new report ... reveals the majority of US consumers using mobile banking applications ... such as fingerprint and voiceprint, instead of having to prove ... to Telstra,s " Mobile Identity   -   The Fusion ... with smartphones now the primary channel used by Gen X ...
(Date:6/11/2015)... June 11, 2015 Daon, a global ... that its IdentityX Mobile Authentication Platform v4.0 has ... Alliance is an industry consortium launched in 2013 ... simpler, stronger authentication.  In order to receive certification, ... rigorous series of tests that measure compliance and ...
(Date:6/9/2015)... 2015 Research and Markets  ( http://www.researchandmarkets.com/research/xsgs2s/gesture ... "Gesture Recognition & Touchless Sensing Market by Technology ... Others), Product (Biometric & Sanitary Equipment) & by ... to their offering. The total gesture ... reach $ 23.55 Billion by 2020 at a ...
Breaking Biology News(10 mins):One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 2One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 3One in Four US Consumers Would Share Their DNA With Their Bank to Secure Financial and Personal Information, Telstra Report Finds 4Daon's IdentityX Mobile Authentication Platform One of First Products to be Certified by FIDO Alliance 2Global Gesture Recognition & Touchless Sensing (Technology, Application & Products) Market 2015-2020 2
... to two-thirds of Earth,s permafrost likely will disappear by ... quantities of carbon into the atmosphere, says a new ... for Research in Environmental Sciences. The ... to thaw in high latitudes from warming temperatures, which ...
... CHAMPAIGN, lll. University of Illinois animal sciences professor ... Prize in Agriculture. He shares the prize with James ... Wolf Prizes are awarded each year, with recipients in ... prize committee selected Lewin for his "highly significant discoveries" ...
... proteins in the blood of pregnant women that could be ... in discovery of biomarkers that seem to be specific enough ... a new study in ACS,s Journal of Proteome Research ... happens when an embryo does not attach normally inside the ...
Cached Biology News:Thawing permafrost likely will accelerate global warming 2Thawing permafrost likely will accelerate global warming 3Illinois professor awarded 2011 Wolf Prize in Agriculture 2
(Date:7/6/2015)... LOS ANGELES , July 6, 2015 ... the establishment of an agreement with Novella Clinical ... of ICT-107 in patients with newly diagnosed glioblastoma. Novella ... clinical trial services to small to mid-sized oncology companies. ... clinical sites in the US, Europe ...
(Date:7/3/2015)... , July 3, 2015 /PRNewswire/ ... hakea verkossa osoitteessa  http://www.openinnovationinscience.at ... Innovation in Science" -jatkokoulutusohjelmaan 22.7.2015 ... Gesellschaftin (LBG) tekemän, kansainvälisiä tutkijoita ... terveystieteiden kaksi suurinta haastetta ovat ...
(Date:7/3/2015)... WIEN , July 3, 2015 /PRNewswire/ ... fram till 22 september 2015 på  http://www.openinnovationinscience.at ... Open Innovation in Science" som hålls i ... Enligt en färsk undersökning med internationella forskare ... Gesellschaft (LBG) är hälsovetenskapens två största utmaningar ...
(Date:7/3/2015)... Forskere kan ansøge ... http://www.openinnovationinscience.at om efteruddannelsesprogrammet "Lab for Open ... Wien .  ... og videnskabsmænd foretaget af Ludwig Boltzmann Gesellschaft ... sundhedsvidenskaben manglen på incitamenter til at undersøge ...
Breaking Biology Technology:ImmunoCellular Therapeutics Establishes Agreement with Novella Clinical to Conduct ICT-107 Phase 3 Registration Trial in Glioblastoma 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 3Lansering av världens första program för öppen innovation för att utbilda forskare 2Lansering av världens första program för öppen innovation för att utbilda forskare 3Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 3
... ANTONIO, Feb. 3 BioComp Pharma, Inc. launched Tinidazole ... Tindamax(R). Tindamax(R) is the only oral antimicrobial drug ... trichomoniasis (trich) and bacterial vaginosis (BV). BioComp Pharma ... February 2009.Generic drugs have the same active ingredients and ...
... Gen-Probe Incorporated (Nasdaq: GPRO ) announced today ... senior vice president, research and development."We are very pleased ... already strong senior management team," said Carl Hull, Gen-Probe,s ... will play an integral role in helping our R&D ...
... 3 Dendreon Corporation,(Nasdaq: DNDN ) today announced ... BIO CEO & Investor Conference in New York City, on,Tuesday, ... A live audio webcast of the presentation will ... http://www.dendreon.com .,If you are unable to listen to the ...
Cached Biology Technology:BioComp Pharma Launches First Generic Drug for Tindamax(R) 2BioComp Pharma Launches First Generic Drug for Tindamax(R) 3Eric Lai Joins Gen-Probe as Senior Vice President, Research and Development 2
...
Anti-VDAC (Voltage-Dependent Anion Channel) AVOID FREEZE/THAW CYCLES. Recognizes the porin 31HL protein. Corresponds to mAb 1 in the literature....
A powerful, easy-to-use solution, the SORVALL RC12BP Blood Processing System allows you to manufacture blood components quickly and cost-effectively while ensuring product quality, safety, and GMP co...
... a recombinant Moloney murine leukemia virus ... is similar to MuLV reverse transcriptase ... MuLV reverse transcriptase is a recombinant ... RNA as a template in the ...
Biology Products: