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Models of eel cells suggest electrifying possibilities
Date:10/2/2008

Engineers long have known that great ideas can be lifted from Mother Nature, but a new paper* by researchers at Yale University and the National Institute of Standards and Technology (NIST) takes it to a cellular level. Applying modern engineering design tools to one of the basic units of life, they argue that artificial cells could be built that not only replicate the electrical behavior of electric eel cells but in fact improve on them. Artificial versions of the eels electricity generating cells could be developed as a power source for medical implants and other tiny devices, they say.

The paper, according to NIST engineer David LaVan, is an example of the relatively new field of systems biology. Do we understand how a cell produces electricity well enough to design oneand to optimize that design? he asks.

Electric eels channel the output of thousands of specialized cells called electrocytes to generate electric potentials of up to 600 volts, according to biologists. The mechanism is similar to nerve cells. The arrival of a chemical signal triggers the opening of highly selective channels in a cell membrane causing sodium ions to flow in and potassium ions to flow out. The ion swap increases the voltage across the membrane, which causes even more channels to open. Past a certain point the process becomes self-perpetuating, resulting in an electric pulse traveling through the cell. The channels then close and alternate paths open to pump the ions back to their initial concentrations during a resting state.

In all, according LaVan, there are at least seven different types of channels, each with several possible variables to tweak, such as their density in the membrane. Nerve cells, which move information rather than energy, can fire rapidly but with relatively little power. Electrocytes have a slower cycle, but deliver more power for longer periods. LaVan and partner Jian Xu developed a complex numerical model to represent the
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Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

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