Navigation Links
Model backs green tea and lemon claim, lessens need to test animals
Date:9/9/2009

WEST LAFAYETTE, Ind. - An animal study at Purdue University has shown that adding ascorbic acid and sugar to green tea can help the body absorb helpful compounds and also demonstrates the effectiveness of a model that could reduce the number of animals needed for these types of studies.

Mario Ferruzzi, associate professor of food science and nutrition, adapted a digestion model with human intestinal cells to show that adding ascorbic acid to green tea would increase the absorbability of catechins found in the tea. Catechins, a class of polyphenols common in tea, cocoa and grape, are antioxidants thought to fight heart disease, stroke, cancer, diabetes and other health problems.

Ferruzzi, Elsa Janle, a Purdue associate research professor of foods and nutrition, and Catrina Peters, a Purdue graduate student in nutrition, were able to demonstrate that adding ascorbic acid, sucrose or both together increases by as much as three times the amount of catechins that can be absorbed into the bloodstream. The results of the in vivo study compared well with those predicted by the in vitro model.

"This model may be used as a pre-emptive screening tool at very little cost before you do expensive tests on animals or humans," said Ferruzzi, whose findings were published in the early online edition of the journal Food Research International. "If you want to get human screening off the ground, it takes months. If you want to use this model, it takes hours."

The model charts how the digestive stability, solubility and absorption of polyphenols changes based on modifications to a beverage's formula. It will not be exact in terms of measurements, but when compared to the in vivo test in rats, the model's predictions matched directionally to the in vivo study and were relatively close proportionately.

Ferruzzi said testing with the model could allow researchers to predict how a new product formula might change the product's prop
'/>"/>

Contact: Brian Wallheimer
bwallhei@purdue.edu
765-496-2050
Purdue University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
2. A new kind of rat model
3. JILA finds flaw in model describing DNA elasticity
4. Smithsonian researchers develop models to assess wetland health
5. Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
6. Simulating kernel production influences maize model accuracy
7. MIT model could improve some drugs effectiveness
8. Model for the assembly of advanced, single-molecule-based electronic components developed at Pitt
9. Improving detection of nuclear smuggling goal of computer model of mechanical engineer
10. New chimeric mouse model for human liver diseases, drug testing
11. Study finds first-ever genetic animal model of autism
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Model backs green tea and lemon claim, lessens need to test animals
(Date:9/21/2014)... autism are significantly less likely to report taking iron ... of children who are developing normally, a study by ... , Low iron intake was associated with a five-fold ... mother was 35 or older at the time of ... conditions such as obesity hypertension or diabetes. , The ...
(Date:9/21/2014)... MA -- In recent years, new strains of bacteria ... Each year, these superbugs, including drug-resistant forms of tuberculosis ... and kill at least 23,000. Despite the urgent need ... classes of antibiotics in the past decade. , MIT ... these superbugs. Using a gene-editing system that can disable ...
(Date:9/19/2014)... Jimmy Durante of dinosaurs a newly discovered ... new dinosaur, named Rhinorex condrupus by ... Young University, lived in what is now Utah ... Cretaceous period. , Rhinorex, which translates roughly into ... relative of other Cretaceous hadrosaurs like Parasaurolophus and ...
Breaking Biology News(10 mins):Mothers of children with autism less likely to have taken iron supplements 2Battling superbugs 2Battling superbugs 3Battling superbugs 4New hadrosaur noses into spotlight 2
... in New Guinea, one of which is the new smallest known ... issue of the online journal PLoS ONE , and the ... University. The new smallest vertebrate species is called Paedophryne ... it was found. The adult body size for these frogs ranges ...
... gene 15 (ISG15), a ubiquitin like protein, is highly ... How the elevated ISG15 pathway contributes to tumorigenic phenotypes ... published in the January 2012 issue of Experimental ... her co-investigators from the Louisiana State University School of ...
... humans arrive in Europe and Asia? At what rate have ... How did Neanderthal teeth and bones differ from ours? These ... Max Planck Weizmann Institute of Science Center in the ... the establishment of the Center is being signed today at ...
Cached Biology News:ISG15: A novel therapeutic target to slow breast cancer cell motility 2Weizmann Institute and Max Planck Society establish a joint center for archaeology and anthropology 2Weizmann Institute and Max Planck Society establish a joint center for archaeology and anthropology 3Weizmann Institute and Max Planck Society establish a joint center for archaeology and anthropology 4
(Date:9/22/2014)... 22, 2014 This is a professional ... M-Phenylenediamine (mPDA) industry in Global and China. The ... definitions, applications and industry chain structure. Global market analysis ... focus on history, developments, trends and competitive landscape of ... situation is also offered. , The report also focuses ...
(Date:9/22/2014)... Research and Markets has announced ... Cellulose Industry Report 2014" report to their offering. ... Industry Report 2014 is a professional and in-depth study ... industry with a focus on the Chinese situation. ... industry including definitions, classifications, applications and industry chain structure. ...
(Date:9/22/2014)...  WIRB-Copernicus Group (WCG), the world,s largest provider ... research, announced today that its Western Institutional Review ... the Association for the Accreditation of Human Research ... for clinical research participants. WCG Chairman ... commented, "It is of utmost importance to WCG ...
(Date:9/21/2014)... Switzerland have succeeded in observing the "forbidden" infrared ... time. These extremely weak spectra offer perspectives for ... also contribute to the development of molecular clocks ... the scientific journal Nature Physics . , ... and light, is probably the most important method ...
Breaking Biology Technology:m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 2m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 3Global and Chinese Microcrystalline Cellulose Industry Report 2014 2Western IRB (WIRB) Awarded AAHRPP Reaccreditation 2Uncovering the forbidden side of molecules 2
... May 29 Sangamo BioSciences,Inc. (Nasdaq: SGMO ... CEO, will provide an update on Sangamo,s diabetic ... 6, 2008, at the Canaccord Adams,Diabetes and Obesity ... be webcast live and may be accessed via ...
... 29 Diplomat Specialty,Pharmacy, a leader in specialty ... (DTM) announced today that their specialty,pharmacy was one ... Roundtable,(NMCRT) held this month in Dallas, Texas. This ... managed care organizations together to,review and improve on ...
... NanoBio(R) Corporation, a,biopharmaceutical company focused on developing ... of infectious diseases, today,announced the appointment of David ... most recently served as President of Pharmaceutical Operations ... David to our Board of Directors and look,forward ...
Cached Biology Technology:Sangamo BioSciences to Present at the Canaccord Adams Diabetes and Obesity Conference 2Diplomat Specialty Pharmacy Sponsors National Managed Care Roundtable for Industry Executive Advisory Board 2David M. Stout Joins NanoBio Corporation's Board of Directors 2
Mouse monoclonal [SIT-01] to SIT ( Abpromise for all tested applications). entrezGeneID: 27240 SwissProtID: Q9Y3P8...
Anti-MMP-25 (Membrane-type MMP-6, Mt6MMP), hinge region; rabbit host...
Anti-MMP-25 (Membrane-type MMP-6, Mt6MMP), hinge region; rabbit host...
Anti-MMP-25 (Membrane-type MMP-6, Mt6MMP), hinge region; rabbit host...
Biology Products: