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'Missing link' discovered in the defence mechanism of the tuberculosis pathogen
Date:11/14/2012

ed the protein mycoredoxin-1, which forms the basis of this ingenious repair mechanism. The scientists analysed the protein structure and the function of the protein and found that mycoredoxin-1 selectively removes mycothiol from affected sulphur-containing proteins and thereby ensures the activation of these proteins. Joris Messens: "We could combat tuberculosis more effectively by searching for components that disable mycoredoxin-1. The bacterium would not be able to recover as quickly from an oxygen attack by our immune system."


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Contact: Joris Messens
info@vib.be
32-478-911-288
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

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