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Misread heart muscle gene a new clue to risk of sudden cardiac death
Date:9/16/2013

rk is particularly important as it represents a new way to uncover interactions of drugs such as flecainide with ARF proteins. The fuller biomedical significance of these unusual, 'mistranslated' proteins is only just becoming recognised."

Dr Suzanne Dilly, Head of Chemical Biology at SEEK, said " I am delighted to see publication of these important results, which were enabled by sharing of expertise and technology between an excellent academic team and our drug discovery group."

Professor of Clinical Pharmacology and Therapeutics Donald Singer said "Adverse effects of drugs can be very serious. Our work shows an unexpected consequence of adverse effects of a drug: providing clues to new causes for disease and new ideas for treatments. There is clear potential to apply these methods to understanding unexplained risks of other medicines".


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Contact: Paul Taylor
p.c.taylor@warwick.ac.uk
44-024-765-24375
University of Warwick
Source:Eurekalert

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