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Minneapolis Heart Institute selected to participate in Cardiovascular Cell Therapy Research Network
Date:4/4/2012

MINNEAPOLIS, April 2, 2012 The Cardiovascular Cell Therapy Research Network (CCTRN), a nationwide U.S. network funded by the National Institutes of Health's (NIH) National Heart, Lung and Blood Institute (NHLBI) has selected the Minneapolis Heart Institute (MHI) as one of its seven U.S. centers of excellence. The network will receive $63 million from the NIH and NHLBI over the next seven years to help achieve its mission of driving public health advances in cardiovascular cell therapy for the treatment of cardiovascular diseases.

MHI was integral to the success of the first CCTRN initiativea series of clinical studies that took place over five years involving five sites using bone marrow stem cells in patients with heart disease, and in which nearly 50 percent of the patients were enrolled in Minnesota. As principal investigator, Timothy D. Henry, MD, director of research at the MHI, will be responsible for a network of Minnesota hospitals including the Minneapolis Heart Institute at Abbott Northwestern Hospital in Minneapolis, the University of Minnesota in Minneapolis, Mayo Clinic in Rochester, United Hospital in St. Paul, Mercy Hospital in Coon Rapids and Hennepin County Medical Center in Minneapolis.

This extension of CCTRN already has three trials planned, including

  • An allogeneic mesenchymal cell for patients with advanced heart function requiring left ventricular assist device;
  • An enhanced autologous bone marrow cell for patients with claudication (leg pain while walking); and
  • A combination of a bone marrow cell and a novel cardiac derived cell for patients with heart failure.

"These trials will play a key role in identifying the benefits of cell therapy in patients with cardiovascular disease. The Minneapolis Heart Institute at Abbott Northwestern Hospital has been a leader in cardiovascular cell therapy research with more than 300 patients treated for a variety of conditions including acute hea
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Contact: Kristin Wincek
kwincek@mhif.org
612-863-0249
Minneapolis Heart Institute Foundation
Source:Eurekalert

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