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Minimizing the spread of deadly Hendra virus
Date:4/15/2009

Groundbreaking CSIRO research into how the deadly Hendra virus spreads promises to save the lives of both horses and humans in the future.

CSIRO Livestock Industries' scientists working at the Australian Animal Health Laboratory (AAHL), in Geelong Victoria, have made a major breakthrough in better understanding how Hendra spreads from infected horses to other horses and humans.

Funded by the Australian Biosecurity CRC for Emerging Infectious Diseases, Dr Deb Middleton and her team at AAHL have defined the period following the first signs of disease when horses are most likely to shed Hendra virus and therefore infect other horses and people.

First identified in Brisbane in 1994, Hendra virus, which spreads from flying foxes, has regularly infected horses in Australia. Of the 11 equine outbreaks, four have led to human infection, with three of the six known human cases being fatal, the most recent of these in August 2008.

Dr Middleton says limited information in the past, on when the disease can transmit, has made it difficult to manage infected horses to stop Hendra spreading further to people and other susceptible horses.

"Our research has also determined the best biological samples required for rapid diagnosis of the virus in horses and identified the important relationship between the period of highest transmission risk and the time with which the disease can easily be detected," Dr Middleton says.

As a result of these findings, veterinarians and horse owners are likely to consider the possibility of Hendra virus infection sooner when dealing with sick horses. This will mean appropriate management strategies can be put in place immediately, reducing the risk of spread while testing is being carried out.

"Unlike in horse flu, where apparently healthy horses can transmit the virus, horses in the early stages of Hendra infection generally appear to be at lower risk compared to animals with
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Contact: Emma Wilkins
Emma.Wilkins@csiro.au
61-352-275-123
CSIRO Australia
Source:Eurekalert

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