Navigation Links
Minimizing the spread of deadly Hendra virus
Date:4/15/2009

Groundbreaking CSIRO research into how the deadly Hendra virus spreads promises to save the lives of both horses and humans in the future.

CSIRO Livestock Industries' scientists working at the Australian Animal Health Laboratory (AAHL), in Geelong Victoria, have made a major breakthrough in better understanding how Hendra spreads from infected horses to other horses and humans.

Funded by the Australian Biosecurity CRC for Emerging Infectious Diseases, Dr Deb Middleton and her team at AAHL have defined the period following the first signs of disease when horses are most likely to shed Hendra virus and therefore infect other horses and people.

First identified in Brisbane in 1994, Hendra virus, which spreads from flying foxes, has regularly infected horses in Australia. Of the 11 equine outbreaks, four have led to human infection, with three of the six known human cases being fatal, the most recent of these in August 2008.

Dr Middleton says limited information in the past, on when the disease can transmit, has made it difficult to manage infected horses to stop Hendra spreading further to people and other susceptible horses.

"Our research has also determined the best biological samples required for rapid diagnosis of the virus in horses and identified the important relationship between the period of highest transmission risk and the time with which the disease can easily be detected," Dr Middleton says.

As a result of these findings, veterinarians and horse owners are likely to consider the possibility of Hendra virus infection sooner when dealing with sick horses. This will mean appropriate management strategies can be put in place immediately, reducing the risk of spread while testing is being carried out.

"Unlike in horse flu, where apparently healthy horses can transmit the virus, horses in the early stages of Hendra infection generally appear to be at lower risk compared to animals with more advanced signs of illness."

These research findings will be used to update the guidelines that horse owners and vets use to handle potential Hendra virus infections.

Dr Middleton says her research also indicates there is an opportunity to diagnose Hendra virus in horses early, prior to advanced clinical signs and the highest risk of transmission.

"Developing a sensitive and specific stall-side test, which vets could use out in the field to diagnose the disease, has become even more important. However there are still key challenges to developing this type of advanced technology."

Although it is still not known how Hendra spreads from flying foxes to horses, Dr Middleton says the key to preventing human exposure and the exposure of additional horses is first understanding the disease in horses and secondly controlling the viral spread from diseased horses.


'/>"/>

Contact: Emma Wilkins
Emma.Wilkins@csiro.au
61-352-275-123
CSIRO Australia
Source:Eurekalert

Related biology news :

1. How cancer spreads by aggregating platelets
2. Lymph nodes can be key in spreading prion infectivity
3. Fighting the spread of food poisoning
4. Dietary calcium could possibly prevent the spread of breast cancer to bone
5. West Nile virus spread through nerve cells linked to serious complication
6. New research to help fight widespread potato disease
7. Widespread support for nonembryonic stem cell research, VCU Life Sciences Survey shows
8. Monkey malaria widespread in humans and potentially fatal
9. Ants and avalanches: Insects on coffee plants follow widespread natural tendency
10. Oregon researchers study widespread areas of low oxygen off northwest coast
11. Inherited cancer mutation is widespread in America
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2016)... Jan. 20, 2016  Synaptics Incorporated (NASDAQ: ... solutions, today announced sampling of S1423, its newest ... and small screen applications including smartwatches, fitness trackers, ... round and rectangular shapes, as well as thick ... with moisture on screen, while wearing gloves, and ...
(Date:1/13/2016)... New York , January 13, 2016 ... Market Research has published a new market report titled ... Growth, Trends, and Forecast, 2015 - 2023. According to the ... in 2014 and is anticipated to reach US$1,625.8 mn ... 2015 to 2023. In terms of volume, the biometric ...
(Date:1/11/2016)... , Jan. 11, 2016  higi, the leading ... 10,000 retail locations, web and mobile, today announced ... million from existing investors. --> ... devoted to further innovate higi,s health platform – ... web portal – including expanding services and programs ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... EDISON, N.J. , Feb. 4, 2016 ... company focused on the development and commercialization of targeted ... BIO CEO & Investor Conference 2016, to be held ... and Source Capital Group,s 2016 Disruptive Growth & Healthcare ... on February 10-11, 2016. James Sapirstein ...
(Date:2/4/2016)... , February 4, 2016 ... Laboratories (ABL), Inc. --> Strasbourg, France ... --> PharmaVentures is pleased to announce that it ... its biopharmaceutical manufacturing unit in Strasbourg, France ... --> --> Transgene (Euronext: ...
(Date:2/3/2016)... -- With the growing need for better therapeutics, and ... such as monoclonal antibodies, recombinant protein therapeutics and ... are in high demand. Conventionally expression systems were ... of these therapeutics. However, due to issues with ... approaches and novel expression systems are currently being ...
(Date:2/3/2016)... ... February 03, 2016 , ... ... a new office dedicated to the North American healthcare market. , Aerocom Healthcare, ... healthcare facilities. The company will provide new pneumatic tube systems or expand ...
Breaking Biology Technology: