Navigation Links
Mini-pig tale provides massive amount of genomic data for human health
Date:11/14/2012

November 15, 2012, Hong Kong, China The international open-access journal GigaScience (a BGI and BioMed Central journal) announces the publication of the whole-genome sequencing and analysis of the Wuzhishan Pig, an extensively inbred, miniature pig, which can serve as an excellent model for human medical research. The availability of the mini-pig genome provides a wealth of genetic tools that will enable detailed and well thought-out analyses on an animal that shares a substantial number of complex diseases with humans. The work here, led by researchers from the BGI, Beijing Institute of Animal Science (IAS), and Chinese Academy of Agriculture Science (CAAS), also revealed potentially actionable resources including the identification of the porcine counterparts of human drug target genes.

Pigs are one of the oldest domesticated livestock species, and as well as providing one of the largest sources of meat worldwide, also provide important medical industrial resources, such as pharmaceutical-grade heparin and heart valves for xenotransplantation. The pig shares many of the same complex genetic diseases as humans, making them excellent models for studying the underlying biology of human disease. Furthermore, the similarity of the pig diet and digestive system with humans makes them ideal for investigation of metabolic diseases and nutritional analyses. The Wuzhishan pig used in this study provides additional advantages for medical analysis: its small size makes it easy to handle; and its long history of inbreeding have resulted in a breed of pigs made up of individuals that are genetically very similar, allowing greater reproducibility in scientific analyses.

To provide the best understanding of the genetics of the Wuzhishan pig and tools for laboratory studies, the researchers at the BGI in collaboration with scientists from several institutions in China and Denmark, carried out whole genome sequencing. They obtained a genome sequenc
'/>"/>

Contact: Scott Edmunds
scott@gigasciencejournal.com
86-755-826-35416
GigaScience
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study provides recipe for supercharging atoms with X-ray laser
2. Mass extinction study provides lessons for modern world
3. Research provides new insights into dogs natural feeding behavior and finds they target a daily dietary intake that is high in fat
4. Study provides first-time analysis of 3 distinct contributions of forage fish worldwide
5. New method provides fast, accurate, low cost analysis of BRCA gene mutations in breast cancer
6. Yak genome provides new insights into high altitude adaptation
7. Innate immune system protein provides a new target in war against bacterial infections
8. Study provides first evidence of coevolution between invasive, native species
9. New discovery provides insight on long-standing pregnancy mystery
10. Study provides new insights into structure of heart muscle fibers
11. New study by WHOI scientists provides baseline measurements of carbon in Arctic Ocean
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... Food and Drug Administration (FDA) for other purposes can ... human cells, including those that cause Legionnaires, disease, brucellosis, ... mBio , the online open-access journal of the American ... non-antibiotic drugs that could one day help curb bacterial ... list inhibit the growth of at least three of ...
(Date:7/28/2014)... coral communities showing signs of damage from the Deepwater Horizon ... in the Gulf of Mexico. The discovery was made by ... Penn State University. A paper describing this work and additional ... Mexico will be published during the last week of July ... Proceedings of the National Academy of Sciences . , "The ...
(Date:7/28/2014)... the South Pole in 1911, but new research shows ... , Using data from 16 ice cores collected from ... South Pole, a group led by Joe McConnell of ... the most accurate and precise reconstruction to date of ... described in an article published today in the online ...
Breaking Biology News(10 mins):New route to identify drugs that can fight bacterial infections 2Impact of Deepwater Horizon oil spill on coral is deeper and broader than predicted 2Lead pollution beat explorers to South Pole, persists today 2Lead pollution beat explorers to South Pole, persists today 3
... NOAA scientists report the discovery of the first known colony of ... A report on the discovery was published last month in the ... name due to its flat-topped, table-like shape, table coral ( Acropora ... of the tropical Pacific, but it has never been observed in ...
... online by the Nature journal Leukemia suggests ... some types of leukemia resist treatment can increase the ... Cincinnati Children,s Hospital Medical Center report that their experimental ... along with chemotherapy was particularly effective at stopping ...
... Calif. , Aug. 8, 2013 The radio frequency ... moving slowly mainly due to high costs and the criticality ... related to food safety and drug traceability in the U.S. ... into the market. New analysis from Frost & ...
Cached Biology News:Study suggests way to fight therapy resistant leukemia by blocking DNA repair 2Study suggests way to fight therapy resistant leukemia by blocking DNA repair 3Frost & Sullivan: Government Mandates Create Momentum in Uptake of Radio Frequency Identification in Global Cold Chain 2Frost & Sullivan: Government Mandates Create Momentum in Uptake of Radio Frequency Identification in Global Cold Chain 3Frost & Sullivan: Government Mandates Create Momentum in Uptake of Radio Frequency Identification in Global Cold Chain 4
(Date:7/29/2014)... (PRWEB) July 29, 2014 The first ... a next generation approach to robotics. What sets Droidles ... patent pending technology that allows them to communicate, share ... wirelessly over the internet. , “The invention is the ... the little Droidles a life of their own, both ...
(Date:7/29/2014)... Eppendorf Centrifuge 5427 R has ... R is geared towards high-end applications like genomic, atomic, ... towards work requiring high sample throughput. Pipette.com is excited ... their extensive 16, 48, and 64 multichannel pipettes as ... tubes, PCR strip tubes, and more. , Introducing ...
(Date:7/29/2014)... The prestigious "Discovery or Exploration in History ... to Juliana Hillis and Kaylie O’Connell, students at Stoneham ... an Egg, Everything: America’s First IVF Baby". This project ... National History Day program during a week-long final competition ... Washington, D.C. , The growing popularity of the assisted ...
(Date:7/29/2014)... Dr. Jason Wendel – recipient of a ... of the Top 10 Plastic Surgeon Specialists for Nashville, TN ... His complete line includes a Hydration Booster, Retexturing Night Crème, ... and skin a younger, more radiant appearance while protecting them ... different, that is why at Dr. J. J. Wendel Plastic ...
Breaking Biology Technology:Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on IndieGoGo.com 2International Pipette Distributor, Pipette.com Announces the Addition of the Eppendorf Centrifuge 5427 R to Their Product Portfolio 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 3Dr. J. J. Wendel Launches New Line of Skin Care Products 2
... MONTREAL and KIEL, Germany, ... researchers at the Kiel- based Collagen,Research Institute (CRI) ... peptides (FORTIGEL(R)) in the context of cell experiments.,Last ... the congress of the,Osteoarthritis Research Society International (OARSI) ...
... , BOZEN, Italy, September 14 ... CytoCare(TM) and i.v.STATION(TM) Robots to,be deployed across all of its ... "After multi-year due diligence on 2 ... on this exciting new technology [due to RIVA,s,publicly announced multi-year ...
... , , , ... Inc. (Nasdaq: CALP ), a leading provider of ... today introduced the IVIS Lumina XR in vivo imaging system, ... XR system combines highly sensitive bioluminescence and fluorescence molecular optical ...
Cached Biology Technology:Important Step Forward in Osteoarthritis Research: Bioactive Collagen Peptides Stimulate the Regeneration of Cartilage Tissue 2Important Step Forward in Osteoarthritis Research: Bioactive Collagen Peptides Stimulate the Regeneration of Cartilage Tissue 3Dr M Group Selects Health Robotics' Technology Over RIVA for all of its I.V. Compounding Centers in South East Asia 2Dr M Group Selects Health Robotics' Technology Over RIVA for all of its I.V. Compounding Centers in South East Asia 3Dr M Group Selects Health Robotics' Technology Over RIVA for all of its I.V. Compounding Centers in South East Asia 4Caliper Life Sciences Launches IVIS(R) In Vivo Imaging System with X-Ray 2Caliper Life Sciences Launches IVIS(R) In Vivo Imaging System with X-Ray 3
... Dot Blot Kits overcome this limitation and ... a wide range in low-density protein array ... They are ideal for performing reverse-phase protein ... for the presence of low abundant antigens. ...
AC input: 50-60 Hz 115-120 V...
... is an aqueous solution that contains ... non-toxic stabilizing chemicals in a MES ... 6.5. This product contains a ... bromonitrodioxane as a preservative. StabilZyme ...
... [3D12] to Lambda Free Light Chain ... light chains of human immunoglobulin. ... constantly expressed epitope of lambda chain. ... of free lambda chains but not ...
Biology Products: