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Microtest Labs Adds Dissolution Testing to its Suite of Analytical and Stability Testing Services
Date:5/26/2009

AGAWAM, Mass., May 13 /PRNewswire/ -- Microtest Laboratories, a leading single source provider of contract analytical solutions, is adding dissolution testing to its current suite of analytical testing and stability testing services.

"The addition of dissolution testing is the perfect complement to our portfolio of services," said Steven Richter, Ph.D., President and Scientific Founder of Microtest Laboratories (www.microtestlabs.com). "By offering an even more comprehensive array of assays, we're increasing the convenience, efficiency, and value that we deliver as a single, preferred provider of contract laboratory services."

For more information about the new service, visit the Microtest website at: www.microtestlabs.com/analytical-chemistry-testing.

Dissolution is a compendial method used to measure a drug's rate of release from its dosage form. It is a complement to other analytical assays -- potency and related substances (Microtest already offers both) -- that characterize the dosage form.

Dissolution is typically used:

  • To optimize drug delivery rate during development studies
  • For use in routine QC analysis for lot release and to measure lot-to-lot variability
  • For use in stability studies to study the effects of time/temperature/humidity on the dosage form
  • To compare one dosage form to another (different formulations, different processes, analysis of competitor's samples)
  • To estimate release and absorption rates in humans after an in vitro -- in vivo correlation is established

Dissolution is a sample preparation technique. Samples still need to be analyzed separately, usually by Microtest's HPLC or UV Spectroscopy testing. Typical samples are oral dosage forms, although it can also be used on topicals and transdermal systems.

In addition to dissolution testing, Microtest provides a host of analytical assays, including HPLC Assays, GC Analysis, Protein Analysis, FTIR Analysis, and UV/VIS Analysis.

Microtest's analytical testing processes follow guidelines from all major standards authorities, including the United States Pharmacopeia (USP), the Japanese and European Pharmacopoeias, the U.S. Food and Drug Administration (FDA), the International Organization for Standardization (ISO), and the Association for Advancement of Medical Instrumentation (AAMI).

For more information, visit the Microtest website at www.microtestlabs.com/analytical-chemistry-testing or call 1-800-631-1680.

Or, visit Microtest at the 2009 Bio International Convention in Atlanta, May 18th-21st, in Booth 2803 in the Massachusetts Pavilion.

About Microtest

Microtest is a leader in testing services and contract manufacturing for the medical device, pharmaceutical, biotechnology industries. Based in Agawam, Massachusetts, USA, the company's expertise and flexible processes enhance product safety and security, accelerate time to market, and minimize supply chain disruption. For more information, visit www.microtestlabs.com or call 1-413-786-1680 or toll-free 1-800-631-1680.

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