Navigation Links
Microbial world's use of metals mostly unmapped
Date:7/19/2010

blication of the journal Nature.

Using state-of-the-art techniques, the team catalogued the metals in three microbes: one that lives in human intestines, one plucked from a hotspring in Yellowstone National Park, and one that thrives in the near-boiling waters of undersea thermal vents.

They uncovered a microbial world far richer in metals than ever expected. For example, in the undersea thermal-vent loving microbe, or Pyrococcus furiosus, they found metals such as lead, manganese, and molybdenum that P. furiosus wasn't known to use.

The scientists traced these newfound metals to the proteins that contain them, called metalloproteins. They discovered four new metalloproteins in the microbe, which increased the number of known metalloproteins in P. furiosus by almost a quarter. Their discovery also increased the number of nickel-containing enzymes in all of biology from eight to ten.

A similar survey of the other two microbes unearthed additional unexpected metals and new metalloproteins. Based on this sizeable haul from only three microbes, the team believes that metalloproteins are much more extensive and diverse in the microbial world than scientists realized.

"We thought we knew most of the metalloproteins out there," says Tainer. "But it turns out we only know a tiny fraction of them. We now have to look at microbial genomes with a fresh eye."

The team used a first-of-its-kind combination of two techniques to envisage this uncharted microbial landscape. Biochemical fractionation enabled them to take apart a microbe while keeping its proteins intact and stable, ready to be analyzed in their natural state. Next, a technology called inductively coupled plasma mass spectrometry allowed them to identify extremely low quantities of individual metals in these proteins.

Together, these tools provide a quick tally of the metalloproteins in a microbe.

The current way to discover metalloprotein
'/>"/>

Contact: Dan Krotz
dakrotz@lbl.gov
510-486-4019
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. When under attack, plants can signal microbial friends for help
2. Unusual microbial ropes grow slowly in cave lake
3. Earths highest known microbial systems fueled by volcanic gases
4. Illinois Soil Nitrogen Test measures microbial nitrogen
5. MIT reels in RNA surprise with microbial ocean catch
6. Exploring standards to advance microbial genomics
7. Reviews of microbial gene language published in special issue of Trends in Microbiology
8. TAXIS Pharmaceuticals licenses novel antimicrobial technology from Rutgers and UMDNJ
9. Model microbial community for studying expanding dead zones characterized
10. UBC researchers find key microbial indicator of ocean health
11. New tool in the fight against mosquito-borne disease: A microbial mosquito net
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... SHELTON, Conn. , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... a biometric authentication company focused on the growing mobile commerce ... consultant, Apollo Robbins for the 2015 International CES ... Apollo Robbins will be at the NXT-ID booth ...
(Date:12/19/2014)... ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced the addition of ... Market" report to their offering. ... market is estimated to grow at a CAGR of 3.6% ... larger share in this market, Canada ...
(Date:12/17/2014)... FORT BELVOIR, Va. , Dec. 15, 2014 ... make it easier to detect and prevent counterfeit microcircuits ... the agency started performing an in-house microcircuit anti-counterfeit initiative ... of purchased microcircuits while increasing their reliability throughout the ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
... (April 29, 2009) How long will it take to ... and reality is closing faster than many people may think. ... measure tissue oxygen and pH will soon be an alternative ... cumbersome equipment to determine metabolic rate. The futuristic system, dubbed ...
... For more than a decade, scientists at Scripps Institution of ... of fault ruptures below the cobalt blue waters of Lake ... the Scripps research team offer a more comprehensive analysis of ... magnitude-7 earthquake occurs every 2,000 to 3,000 years in the ...
... approaches and methodology employed by plant and molecular biologists, ... be applied to plant cells in the newly funded ... Energy, Energy Frontier Research Center at Penn State. ... million over five years. Daniel J. Cosgrove, professor of ...
Cached Biology News:Star Trek-like technology offers noninvasive monitor for patients and athletes 2Star Trek-like technology offers noninvasive monitor for patients and athletes 3Scripps studies offer new picture of Lake Tahoe's earthquake potential 2Center to investigate plant cells for better biomass fuels 2
(Date:1/22/2015)... The laboratory information management systems market is a ... technological advancements due to factors such as rising pressure ... healthcare systems, and increasing government support for adoption of ... players in the market focus on technological advancements to ...
(Date:1/22/2015)... Boulder, CO / Rootstown, OH (PRWEB) January 22, 2015 ... sensitive detection platform, announced today that it has received AOAC-PTM ... O26, O45, O1O3, O111, O121, and O145; collectively referred to ... (E. coli) O157, at 1 colony forming unit (cfu) per ...
(Date:1/22/2015)... zFlo Motion , a US leader ... exciting product from a new partner. STT-Systems has ... past 15 years, with offerings in the optical-motion capture, 3D ... system (inertial measurement unit), iSen, is opening eyes around the ...
(Date:1/22/2015)... 22, 2015 Controlled Substance Compliance Services ... helps companies check the legal requirements around using controlled ... China. , As their international operations expand and ... software solutions built as a result of the first ...
Breaking Biology Technology:Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 23D Motion Capture Just Got Easy 2Global Compliance Service for Controlled Substances to Expand to China 2
... /PRNewswire/ - Edmonton will be home to the,world,s ... municipal,solid waste. The City has signed a 25-year ... Enerkem, a leading biofuels,technology company., The $70 ... of biofuels per year and reduce Alberta,s carbon ...
... Key Senior Scientist Promotions Announced, ROCKVILLE, Md. ... Craig Venter Institute (JCVI), a not-for-profit genomic research,organization, ... named,the new Deputy Director of the JCVI La ... of several key science leaders --,Karen Nelson, Ph.D., ...
... Highlights Include:, -- GSK,s ROTARIX(R) [Rotavirus ... to protect against rotavirus gastroenteritis,(RGE), -- ROTARIX, ... is the only rotavirus,vaccine that offers completion of ... two oral doses, -- GSK,s KINRIX(TM) [Diphtheria ...
Cached Biology Technology:Edmonton to be site of world's first industrial scale municipal waste-to-ethanol facility 2Edmonton to be site of world's first industrial scale municipal waste-to-ethanol facility 3Edmonton to be site of world's first industrial scale municipal waste-to-ethanol facility 4Edmonton to be site of world's first industrial scale municipal waste-to-ethanol facility 5J. Craig Venter Institute Names Robert Friedman, Ph.D., Deputy Director of West Coast Facility 2J. Craig Venter Institute Names Robert Friedman, Ph.D., Deputy Director of West Coast Facility 3J. Craig Venter Institute Names Robert Friedman, Ph.D., Deputy Director of West Coast Facility 4J. Craig Venter Institute Names Robert Friedman, Ph.D., Deputy Director of West Coast Facility 5CDC Immunization Advisory Committee Recommends Two New Pediatric Vaccines from GlaxoSmithKline 2CDC Immunization Advisory Committee Recommends Two New Pediatric Vaccines from GlaxoSmithKline 3CDC Immunization Advisory Committee Recommends Two New Pediatric Vaccines from GlaxoSmithKline 4CDC Immunization Advisory Committee Recommends Two New Pediatric Vaccines from GlaxoSmithKline 5CDC Immunization Advisory Committee Recommends Two New Pediatric Vaccines from GlaxoSmithKline 6
... IDS EIA kit is a complete assay ... D (1,25D) in human serum or plasma. ... system found in the IDS 1,25D RIA ... assay comes with ready to use reagents, ...
... is a molecular screening, low melting point ... sieving. It is recommended for separation of ... such as PCR products. Micro ABgarose is ... not recommended for blotting techniques. At a ...
Rabbit polyclonal to L Kynurenine ( Abpromise for all tested applications). Antigen: Synthetic peptide L Kynurenine conjugated to a protein carrier. Entrez Gene ID: 8942 Swiss Protein ID...
Sheep polyclonal to Salmonella Shoreditch ( Abpromise for all tested applications). Antigen: Native Salmonella shoreditch (Group D2)....
Biology Products: