Navigation Links
Micro-origami: USC folds up micrometer-scale 'voxels' for drug delivery
Date:4/29/2008

Researchers at the USC Information Sciences Institute have demonstrated a way to manufacture miniscule closed containers that might be used to deliver precise micro- or even nano-quantities of drugs.

According to ISI project leader Peter Will, who is also a research professor in the Viterbi School of Engineering, the new technique, described in a paper in the Journal of Micromechanics and Microengineering, is a two-step process.

Part one is the creation of flat patterns, origami, of exactly the fold up shapes familiar to kindergarten children making paper pyramids, cubes or other solids, except that these are as small 40 micrometers (m) on a side. (1 inch = 25,400 m)

Instead of paper, the USC researchers created the patterns in polysilicon sitting on top of a thin film of gold, using a well-established commercial silicon wafer process called PolyMUMPs. The next step was clearing the polysilicon off the hinge areas by etching.

When the blanks were later electrocoated with permalloy to make them magnetic, the photomask used left hinge areas uncoated, to make sure they were the places that folded.

Then the folding had to be accomplished. First the researchers bent the hinges by application of magnetic force to the permalloy. Water pressure and capillary forces generated by submerging the tiny blanks in water, and drying them off did the final folding into shape.

The experiments spend considerable time comparing various methods of controlling the closure effects of water drying with simple flaps designed to close over each other to form "envelops," the directing water from different directions sequence the closing. Varying the time of trying could produce tighter seams.

"Our experiments show" says the paper, that "the combination of partial folding of structures by magnetic actuation and liquid closure to bring the structures to their final closed state is an extremely promising techni
'/>"/>

Contact: Eric Mankin
310-448-9112
University of Southern California
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Fewer babies born after Caesarean delivery
2. Remarks Prepared for Delivery By Attorney General Michael B. Mukasey At the Ministerial Press Conference
3. e-SMART Technologies Continues Delivery of Its New Super SMART Card in South Korea
4. Researchers develop better membranes for water treatment, drug delivery
5. Carnegie Mellon researchers to develop new drug delivery system
6. Computer solution to delivery problem
7. Nanoengineers mine tiny diamonds for drug delivery
8. Jumping genes could make for safer gene delivery system
9. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Micro-origami: USC folds up micrometer-scale 'voxels' for drug delivery
(Date:8/29/2014)... has been known about what genetic changes transform wild ... one of whom is a University of Montana assistant ... controlling the development of the brain and the nervous ... was published Aug. 28 in Science and ... at http://www.sciencemag.org/ ., The domestication of animals and ...
(Date:8/29/2014)... number of connections in transcription factor networks (TFNs) to ... study published in PLOS Computational Biology in ... contributes to a network,s resilience against mutations. , ... of TFN models has a greater effect on robustness ... assortativity," said Dov A. Pechenick, PhD, lead author and ...
(Date:8/29/2014)... the prolific bloomer Emiliania huxleyi , can grow ... finding contradicts the common view that E. huxleyi ... supplies of thiamine in the ocean to survive. , ... ocean," says CIFAR Senior Fellow Alexandra Worden , ... CIFAR fellows John Archibald (Dalhousie University), ...
Breaking Biology News(10 mins):New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3Assortativity signatures of transcription factor networks contribute to robustness 2Not all phytoplankton in the ocean need to take their vitamins 2Not all phytoplankton in the ocean need to take their vitamins 3
... energy, can yield up to five times more biofuel if ... grow naturally up towards the sky. This effect had ... UK, but scientists were previously unable to explain why some ... have identified a genetic trait that causes this effect and ...
... With a new insight into a model of Parkinson,s ... Veterinary Medicine have identified a novel target for mitigating ... Narayan G. Avadhani, Harriet Ellison Woodward Professor of Biochemistry ... Penn Vet, was the senior author on the research. ...
... coming decades, climate change will lead to more frequent and ... quality and threatening public health. Intense rainstorms and floods will ... will be exacerbated. Those are some of the conclusions ... last week by the federal government that assesses the key ...
Cached Biology News:Wind in the willows boosts biofuel production 2Penn Vet study reveals a promising new target for Parkinson's disease therapies 2Climate change to profoundly affect the Midwest in coming decades 2Climate change to profoundly affect the Midwest in coming decades 3
(Date:8/28/2014)... NEW YORK , Aug. ... announces that a new market ... its catalogue: Whole ... (Systems, Kits (Library Preparation, Target ... Technology (Sequencing by Synthesis), by ...
(Date:8/28/2014)... , Aug. 28, 2014   SunTrust Robinson ... three industry veterans to its equity research team ... "Our ongoing expansion in equity research demonstrates our ... unique insights to enhance their investment decision making," ... at STRH.  "We continue to make significant investments ...
(Date:8/28/2014)... by a Florida State University research team has led ... temperature, emit white light, and convert photon energy directly ... a butterfly. , Biwu Ma, associate professor in the ... College of Engineering, created the molecule in a lab ... that his creation has many other unique capabilities. , ...
(Date:8/28/2014)... Earlier this month, a report was created ... U.S. Air Force on the performance of vehicles using ... type of fuel made from mustard seeds, offered great ... America’s Eco friendly future. In fact, every branch of ... independent of foreign oil over the next few years. ...
Breaking Biology Technology:Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 2Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 3Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 4Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 5Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 6Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 7Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 8Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 9Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 10Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 11Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 12Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 13SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 3Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 4Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 5
... Calif., Oct. 12, 2011 Life Technologies Corporation ... innovative new research products, including the Ion Sequencing 200 Kit, ... Machine™ sequencer is now the only next-generation sequencer that can ... day. " Nine months after our ...
... deCODE genetics ... collaboration with Pfizer Inc., the objective of which is ... related to Systemic Lupus Erythematosis by utilizing deCODE,s expertise ... its extensive population and genetic resources, including DNA samples ...
... Oct. 12, 2011 StriVectin®, the clinical anti-aging expert, ... Cancer Foundation,s 2011 Skin Sense Award Tuesday night at ... gala, honors exceptional achievement in skin health.  The company ... proprietary technology rooted in 30 years of research into ...
Cached Biology Technology:Ion Torrent Gets Better Faster With 4th Qtr New Product Releases 2Ion Torrent Gets Better Faster With 4th Qtr New Product Releases 3Ion Torrent Gets Better Faster With 4th Qtr New Product Releases 4Ion Torrent Gets Better Faster With 4th Qtr New Product Releases 5deCODE Announces Agreement With Pfizer to Search for Variants in the Human Genome That Confer Risk of Systemic Lupus Erythematosis 2StriVectin® Receives Annual Skin Sense Award 2
... compact, lightweight, high current power supply capable of ... It is an excellent choice for PAGE, SDS-PAGE ... also ideal for all types of electroblotting applications.A ... automatically end a run and wil automatically accrue ...
... Vapor Trap Models RVT100, RVT400, RVT405DDA, RVT4104 ... UVS400A and UVS800DDA., A non-corrosive, odorless specially ... temperatures ranging from -105 to +260 degrees ... does not evaporate. Far superior to dry ...
... of proteomics demands the detection of very ... of the AXIMA-CFRplus with improved resolution (20,000) ... provides increased confidence in protein identification. The ... sensitivity, automated sample target handling and the ...
... The standard of the Axima ... of high mass accuracy, resolution, sensitivity ... versatility with both linear and reflectron ... field reflectron enables the generation of ...
Biology Products: