Navigation Links
Michigan Tech scientists identify genes linked to Lou Gehrig's disease
Date:9/9/2009

Michigan Technological University researchers have linked three genes to the most common type of amyotrophic lateral sclerosis (ALS), generally known as Lou Gehrig's disease.

Professor Shuanglin Zhang leads the team of mathematicians that isolated the genes from the many thousands scattered throughout human DNA. He notes that their discovery does not mean an end to ALS, but it could provide scientists with valuable clues as they search for a cure.

It can't come any too soon. Zhang started showing symptoms of the disease himself four years ago. He now breathes with support from a respirator and works at home with the aid of a research assistant and his wife, Qiuying Sha, an assistant professor and member of his research team.

"I felt very urgent to find the genes for ALS," he says.

"This is very nice work," said Xiaofeng Zhu, an associate professor of epidemiology at Case Western Reserve University's School of Medicine. "It's very challenging to map genes for complex diseases, and while many statistical methods have been developed, most don't work well in practice. Zhang's group has developed a method to detect genes and gene-gene interaction in complex diseases and provided evidence that it works.

"Their findings will need to be confirmed by other researchers, but I think this will be very useful for the investigators who are trying to find genes underlying complex diseases such as ALS," said Zhu.

According to the ALS Association, only about 10 percent of patients have familial ALS, a directly inherited form of the usually fatal neuromuscular disorder. The remaining 90 percent, including Zhang, are diagnosed with the sporadic form of the disease. While scientists have long suspected that genetics plays a role in sporadic ALS, they have had no evidence to back it up, at least until now.

Everyone has the three genes in question. But in people with sporadic ALS, they differ from those in people who
'/>"/>

Contact: Marcia Goodrich
mlgoodri@mtu.edu
906-487-2343
Michigan Technological University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Climate change driving Michigan mammals north
2. University of Michigan installs second Genomatix Genome Analyzer
3. Lake Michigan fish populations threatened by decline of tiny creature
4. Michigan Tech researchers link 11 genetic variations to type 2 diabetes
5. Scientists discover new genetic variation that contributes to diabetes
6. Einstein scientists move closer to a safer anthrax vaccine
7. Scientists begin to untangle root cause of Alzheimers disease
8. NOAA scientists map fish habitat and movements at Grays Reef Marine Sanctuary
9. Scientists study possible responses to climate emergencies
10. Finding the ZIP-code for gene therapy: Scientists imitate viruses to deliver therapeutic genes
11. Caltech neuroscientists find brain region responsible for our sense of personal space
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Michigan Tech scientists identify genes linked to Lou Gehrig's disease
(Date:8/11/2015)... Today, ZUK announced its Android smartphone Z1, ... expected revenues in 2015 that relate to sales of FPC1155 for ... approximately 2,200 MSEK for 2015. Jörgen Lantto, CEO of ... smartphone manufacturer in China and ... 155 for Z1 , ...
(Date:8/6/2015)... JOSE, Calif. , Aug. 6, 2015 /PRNewswire/ ... leading developer of human interface solutions, today announced ... TouchPad technologies on Windows 10. Microsoft leveraged Synaptics, ... to the operating system. Through ... drivers are fully certified with Microsoft,s Precision TouchPad ...
(Date:8/4/2015)...  AMRI (NASDAQ: AMRI ) today reported financial and operating ... Highlights: , Second quarter contract revenue of $ ... , Adjusted contract margins of 26 % ... $0.05 decrease in EPS from royalties in the current quarter ... "We are very pleased to present another strong financial quarter, ...
Breaking Biology News(10 mins):FPC's Touch Fingerprint Sensor FPC1155 in ZUK's Smartphone Z1 2Synaptics Chosen for Human Interface Co-Development on Windows 10 2AMRI Announces Second Quarter 2015 Results 2AMRI Announces Second Quarter 2015 Results 3AMRI Announces Second Quarter 2015 Results 4AMRI Announces Second Quarter 2015 Results 5AMRI Announces Second Quarter 2015 Results 6AMRI Announces Second Quarter 2015 Results 7AMRI Announces Second Quarter 2015 Results 8AMRI Announces Second Quarter 2015 Results 9AMRI Announces Second Quarter 2015 Results 10AMRI Announces Second Quarter 2015 Results 11AMRI Announces Second Quarter 2015 Results 12AMRI Announces Second Quarter 2015 Results 13AMRI Announces Second Quarter 2015 Results 14AMRI Announces Second Quarter 2015 Results 15AMRI Announces Second Quarter 2015 Results 16AMRI Announces Second Quarter 2015 Results 17AMRI Announces Second Quarter 2015 Results 18AMRI Announces Second Quarter 2015 Results 19AMRI Announces Second Quarter 2015 Results 20AMRI Announces Second Quarter 2015 Results 21AMRI Announces Second Quarter 2015 Results 22AMRI Announces Second Quarter 2015 Results 23AMRI Announces Second Quarter 2015 Results 24
... University of Alaska Fairbanks researchers Igor Semiletov and Donald ... press briefing, The Arctic in Flux: New Insights from ... a.m. Pacific Standard Time at the American Geophysical Union ... The briefing will present early results from a ...
... Springer to publish its official publication The Journal ... Volume 59, Number 1. The bimonthly journal was ... The journal will join Springer,s strong portfolio of ... Brain Research and Pflgers Archiv: European Journal ...
... fish in ocean cages is fundamentally harmful to wild fish, ... . Using basic physics, Professor Neil Frazer of the ... at Manoa explains how farm fish cause nearby wild fish ... density of fish promotes infection, and infection lowers the fitness ...
Cached Biology News:UAF researchers to present at AGU press briefing 2UAF researchers to present at AGU press briefing 3UAF researchers to present at AGU press briefing 4UAF researchers to present at AGU press briefing 5UAF researchers to present at AGU press briefing 6Springer and the Physiological Society of Japan sign publishing agreement 2Ocean fish farming harms wild fish, study says 2
(Date:8/31/2015)... Aug. 31, 2015  For people with Down syndrome, ... day. The biotechnology company, located in the Science + ... the best potential therapies yet for people with Down syndrome ... Correction of Down syndrome and Edwards syndrome aneuploidies in ... DNA Research . Elixirgen plans to develop this technology ...
(Date:8/31/2015)... FRANCISCO, Calif. , Aug. 31, 2015 ... discovery and development of novel cancer immunotherapies, announced today ... Ph.D., as Chief Executive Officer and William Ho ... and Ho join an experienced management team led by ... Jordan Fridman , Ph.D., Chief Scientific Officer; Jay ...
(Date:8/31/2015)... ... August 31, 2015 , ... There’s a new treatment option for ... first commercially available new FDA approved system in the last 14 years, and the ... high Amenorrhea (zero bleeding) rate of 66%, the high Patient Satisfaction rate of 98%, ...
(Date:8/28/2015)... ... August 28, 2015 , ... Proove Biosciences ... the International Spine Intervention Society’ s 23rd Annual Scientific Meeting (ASM). ... 2015. With a focus on evidence-based research and clinical application, the event gathered ...
Breaking Biology Technology:New Down syndrome therapy discovered 2FLX Bio Announces Senior Management Hires and Initiation of Phase 1 Trial of FLX925 2FLX Bio Announces Senior Management Hires and Initiation of Phase 1 Trial of FLX925 3FLX Bio Announces Senior Management Hires and Initiation of Phase 1 Trial of FLX925 4U.S. FDA Approves Minerva Endometrial Ablation System 2U.S. FDA Approves Minerva Endometrial Ablation System 3Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 2Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 3Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 4
... Inc. announced that the launch of a new ... of cancer treatments.  BioSpeciFx® is composed of carefully ... biomarker tests that identify critical molecular targets within ... by BioSpeciFx® in combination with Precision,s sophisticated drug ...
... Texas, April 7, 2011 Wound Management Technologies, Inc., ... leader in advanced wound care solutions, today announced that ... care products within key international markets, has received new ... gel products.  In Lebanon, the subsidiary just completed a ...
... Reportlinker.com announces that a new market research report ... Industrial Biotechnology China News 1103 ... government was reported to continue intensifying the demand ... (2011-2015) Plan. This act is expected to help ...
Cached Biology Technology:Precision Therapeutics Announces New Tumor Profiling Product to Augment Utility of ChemoFx® and Further Personalize Cancer Treatment 2WNDM Secures Additional International Sales; $150 K in New Orders for 2011 2WNDM Secures Additional International Sales; $150 K in New Orders for 2011 3Reportlinker Adds Industrial Biotechnology China News 1103 2Reportlinker Adds Industrial Biotechnology China News 1103 3
... The BioLogic Maximizer kit, 110 ... and pH monitoring and doubles flow ... DuoFlow chromatography systems. The kit includes ... Maximizer mixer, starter kit, tubing kit, ...
... antifade reagent is used to ... standard fluorescence microscopy. The unique ... a wide variety of fixed ... fluorescein, rhodamine, sulforhodamine 101, coumarin, ...
... FAST RED Chromogen System consists of FAST ... reacts in the presence of alkaline phosphatase ... noise. The FAST RED System provides ... System Contains: , , Vial A: 6 ...
... Dodeca silver stain kits are optimized ... including Bio-Rad Dodeca stainers. This silver ... of proteins in polyacrylamide gels and ... includes sensitizer concentrate, silver reagent concentrate, ...
Biology Products: