Navigation Links
Michael J. Fox Foundation awards $2.4M for validation of therapeutic targets for Parkinson's
Date:7/17/2008

eatment has been proven to do.

Two investigators will be continuing projects initiated under previous MJFF programs, reflecting the Foundation's desire to keep promising work moving forward quickly. Stephen F. Traynelis, PhD, of Emory University was funded under MJFF's Community Fast Track 2005 initiative to screen small-molecule compound libraries for molecules that inhibit a certain type of brain receptor called the NR2D-containing NMDA receptor in the basal ganglia, a part of the brain involved in Parkinson's disease. His new award will allow him to take this work to the next level, testing these molecules to see if they can reduce PD-like symptoms in rodent models. Kalipada Pahan, PhD, of Rush University is investigating a protein called NF-kB, which is involved in the inflammation process that some believe might trigger or promote continued loss of cells in the Parkinson's brain. Dr. Pahan has already shown that delivering specific inhibitors against NF-kB is neuroprotective in a rodent model of Parkinson's. He will now work to confirm his results in a non-human primate model of PD as the next step toward possible clinical trials.

Other investigators will be looking at various targets for possible relevance to therapeutic strategies for PD. Danny G. Winder, PhD, and Roger J. Colbran, PhD, both at Vanderbilt University and Ann M. Graybiel, PhD, at the Massachusetts Institute of Technology are each investigating new targets for possible roles in the development of dyskinesias. To identify strategies that could protect from loss of brain cells in PD, investigators Pamela J. McLean, PhD, of Massachusetts General Hospital (Harvard University), Malu G. Tansey, PhD, of University of Texas Southwestern Medical Center and Benjamin Wolozin, MD PhD, of Boston University School of Medicine will manipulate various proteins in PD animal models. Finally, Yvette F. Tache, PhD, of the University of California, Los Angeles, has developed a possible rodent mod
'/>"/>

Contact: Holly Barkhymer
hbarkhymer@michaeljfox.org
212-509-0995 x242
The Michael J. Fox Foundation for Parkinson's Research
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors
2. American Society for Microbiology honors Michael Bruce Zwick
3. Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors
4. Remarks Prepared for Delivery By Attorney General Michael B. Mukasey At the Ministerial Press Conference
5. Neuroscientist Michael Gazzaniga awarded Humboldt Prize
6. Balzan Foundation announces 2007 winners
7. Keck Foundation funds study of biological interactions with nanomaterials
8. Yu receives research funding from the Wallace H. Coulter Foundation
9. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. Arizona State University launches biofuel initiative with BP and Science Foundation Arizona
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Technology Showcase, Hall E -   EyeLock Inc. , ... it will showcase its EyeLock ID technology integrated in a ... Energy,s Oak Ridge National Laboratory (ORNL) at the ... identity authentication technology is being used to validate the driver ...
(Date:1/22/2015)...  Analyst Report Issued by Small Cap IR. In 2011, Nilson ... transactions at merchants on the leading payment cards rose to ... debit, and prepaid cards reached 6.54 billion.  Eight million credit ... usage in 2012, and credit and debit card fraud resulted ...
(Date:12/24/2014)... its launch in December 2014, the 1U™ app ... trying to remember their usernames and passwords through replacing the ... To assist people who have struggled to remember usernames and ... and focuses on redefining identity, announced today that it is ...
Breaking Biology News(10 mins):EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3
... of the International Society for Sexually Transmitted Disease Research ... City, Canada. The world,s foremost conference in the ... from every continent to discuss the most recent developments ... emerging threats in bacterial STDs; major intervention programs for ...
... University of Georgia researcher has invented a new ... clothing, face masks, paper towelsand yes, even diapers, ... germ-free. The simple and inexpensive anti-microbial technology ... can be applied during the manufacturing process or ...
... are developing new technologies that combine a laser ... particles such as bacteria, viruses and DNA for ... to food safety. The technologies could bring ... or miniature instruments that perform measurements normally requiring ...
Cached Biology News:New UGA technology makes textiles permanently germ-free; targets health care-associated infections 2New UGA technology makes textiles permanently germ-free; targets health care-associated infections 3Laser, electric fields combined for new 'lab-on-chip' technologies 2Laser, electric fields combined for new 'lab-on-chip' technologies 3
(Date:1/23/2015)... Portal Solutions , a technology consulting ... Microsoft Office 365 and SharePoint platforms , today announces its ... being one of the region’s fastest-growing mid-sized companies based on ... , “To be recognized a second year in a row ...
(Date:1/22/2015)... 22, 2015 GEA Niro Soavi the ... laboratory homogenizer, the PandaPLUS 2000, which is ideal for ... and cell disruption . This compact laboratory homogenizer ... juices, liquid food, food additives and ingredients as well ...
(Date:1/22/2015)... Protocol Networks brings independent technology consulting ... brand-neutral, independent consultants, Protocol Networks has recently announced its ... the years, his company has attracted several clients in ... as well as others. With the success of these ...
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently was invited to ... on probiotics in San Diego, CA. , The Scripps ... health care professionals. This year’s pre-conference seminar was held on ... Dr. Leyer spoke about the emerging topics and science in ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... Turner Fellow at Stony Brook University (SBU), will give ... in Philadelphia on controlling the size of nanoclusters, research ... Department of Energy,s Brookhaven National Laboratory. Built by Brookhaven ... make nanoclusters of 10 to 100 atoms with atomic ...
... Technology (NIST) and the Joint Quantum Institute (JQI), a ... have reported a new way to fine-tune the light ... of lasers. Their technique, published in Physical Review ... source of pairs of entangled photons, a property with ...
... New Contracts Valued at $115.5 Million Signed in Fourth ... ARAY ), a global leader in the field ... and fiscal year,ended June 28, 2008., For the ... $50.9 million, a 16 percent increase over fourth quarter ...
Cached Biology Technology:Light touch: Controlling the behavior of quantum dots 2Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 2Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 3Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 4Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 5Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 6Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 7Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 8Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 9
... the Axima range, the AXIMA-CFR provides ... resolution, sensitivity and mass range, and ... and reflectron time-of-flight analysis. The unique ... generation of seamless PSD, providing efficient ...
... The new MALDI O-TOF creates a new ... an orthogonal platform that has been licensed ... University of Manitoba. , As the first ... design and collisional cooling, the prOTOF 2000 ...
Rat Lung Fibroblasts (RLF) (>500,000 cells)...
Rat Aortic Endothelial Cells (RAOEC) (>500,000 cells)...
Biology Products: