Navigation Links
Mice can inherit learned sensitivity to a smell
Date:12/2/2013

Trauma can scar people so indelibly that their children are affected. History provides examples of generations traumatized by war and starvation, whose children experience altered physiology.

Now researchers at Yerkes National Primate Research Center, Emory University have found an instance of animals passing on more specific information about a traumatic experience to their offspring. That information comes not through social communication, but through inheritance.

Researchers have found that when a mouse learns to become afraid of a certain odor, his or her pups will be more sensitive to that odor, even though the pups have never encountered it.

The results were published online Dec. 1, 2013 in Nature Neuroscience.

"Knowing how the experiences of parents influence their descendants helps us to understand psychiatric disorders that may have a trans-generational basis, and possibly to design therapeutic strategies," says senior author Kerry Ressler, MD, PhD, professor of psychiatry and behavioral sciences at Emory School of Medicine.

Ressler is a Howard Hughes Medical Institute-supported investigator at Yerkes National Primate Research Center, Emory University. The first author of the paper is postdoctoral fellow Brian Dias, PhD.

Dias and Ressler trained mice to become afraid of an odor, by pairing exposure to the odor with a mild electric shock. They then measured how much the animal startled in response to a loud noise at baseline, and in conjunction with presentation of the odor.

Surprisingly, they found that the nave adult offspring of the sensitized mice also startled more in response to the particular odor that one parent had learned to fear. In addition, they were more able to detect small amounts of that particular odor. Smell-sensitized offspring were not more anxious in general; Dias found that they were not more afraid to explore the exposed areas of a maze.

Dias
'/>"/>

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Inherited gene variation tied to high-risk pediatric leukemia and greater risk of relapse
2. New research on inherited herpesvirus may have implications for transplantation
3. Inheritance of lifespan is sex-dependent in fruit flies
4. Gene mutations caused by a fathers lifestyle can be inherited by multiple generations
5. Non-inherited mutations account for many heart defects, Yale researchers find
6. Cell discovery could hold key to causes of inherited diseases
7. Defying the laws of Mendelian inheritance
8. Born to lead? Leadership can be an inherited trait, study finds
9. Researchers discover 2 genetic flaws behind common form of inherited muscular dystrophy
10. Scientists uncover mechanism by which plants inherit epigenetic modifications
11. The Johns Hopkins Center for Inherited Disease Research receives $101 million
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mice can inherit learned sensitivity to a smell
(Date:2/13/2015)... 2015 ACT Genomics Co., Ltd., a ... transform cancer genomic information into precision diagnosis and ... raised US$ 8 million in the its first private ... Taipei, Taiwan , ACT Genomics has developed ... aim to implement next generation sequencing (NGS) and ...
(Date:2/10/2015)... -- Alere Inc. (NYSE: ALR), a global leader in ... quarter ended December 31, 2014. Namal ... said, "We made substantial progress in the fourth ... in rapid diagnostics and delivering against our financial ... early January enabled us to substantially reduce our ...
(Date:2/5/2015)... 2015   Epic Sciences , a precision diagnostics company ... Murali Prahalad , Ph.D., president and CEO, is scheduled ... (PMWC) 2015: Silicon Valley, which is taking place at the ... on January 26-28, 2015. Dr. Prahalad ... Biomarkers." Last year, Epic Sciences was a finalist in the ...
Breaking Biology News(10 mins):ACT Genomics Raises $8 Million in its First Private Funding Round 2Alere Inc. Announces Fourth Quarter 2014 Results 2Alere Inc. Announces Fourth Quarter 2014 Results 3Alere Inc. Announces Fourth Quarter 2014 Results 4Alere Inc. Announces Fourth Quarter 2014 Results 5Alere Inc. Announces Fourth Quarter 2014 Results 6Alere Inc. Announces Fourth Quarter 2014 Results 7Alere Inc. Announces Fourth Quarter 2014 Results 8Alere Inc. Announces Fourth Quarter 2014 Results 9Alere Inc. Announces Fourth Quarter 2014 Results 10Alere Inc. Announces Fourth Quarter 2014 Results 11Alere Inc. Announces Fourth Quarter 2014 Results 12Alere Inc. Announces Fourth Quarter 2014 Results 13Alere Inc. Announces Fourth Quarter 2014 Results 14Alere Inc. Announces Fourth Quarter 2014 Results 15Alere Inc. Announces Fourth Quarter 2014 Results 16Alere Inc. Announces Fourth Quarter 2014 Results 17Alere Inc. Announces Fourth Quarter 2014 Results 18Alere Inc. Announces Fourth Quarter 2014 Results 19Alere Inc. Announces Fourth Quarter 2014 Results 20Alere Inc. Announces Fourth Quarter 2014 Results 21Alere Inc. Announces Fourth Quarter 2014 Results 22Alere Inc. Announces Fourth Quarter 2014 Results 23Alere Inc. Announces Fourth Quarter 2014 Results 24Alere Inc. Announces Fourth Quarter 2014 Results 25Alere Inc. Announces Fourth Quarter 2014 Results 26Alere Inc. Announces Fourth Quarter 2014 Results 27Alere Inc. Announces Fourth Quarter 2014 Results 28Alere Inc. Announces Fourth Quarter 2014 Results 29Alere Inc. Announces Fourth Quarter 2014 Results 30Alere Inc. Announces Fourth Quarter 2014 Results 31Alere Inc. Announces Fourth Quarter 2014 Results 32Alere Inc. Announces Fourth Quarter 2014 Results 33Alere Inc. Announces Fourth Quarter 2014 Results 34Alere Inc. Announces Fourth Quarter 2014 Results 35
... New York, NYDecember 7, 2011Thanks to a new ... be able to diagnose in their offices non-periodic ... Non-periodic arrhythmias include atrial and ventricular fibrillation, which ... can in some cases be life-threatening. ...
... Scientists at Warwick Medical School have made an ... switch, shedding new light on our understanding of how ... led by Professor Victor Zammit, Head of Metabolic and ... enzyme known as ,Carnitine palmitoyltransferase 1A, (CPT1) has a ...
... (HE), in which hydrogen would replace the carbon-based fossil fuels ... Today, HE is seen as a potential solution to the ... A research paper to be published in the International ... and SHE has the answer in the sustainable hydrogen economy. ...
Cached Biology News:New Columbia engineering technique diagnoses non-periodic arrhythmias in a single heartbeat 2Building a sustainable hydrogen economy 2
(Date:3/2/2015)... Calif. , March 2, 2015 ... company developing therapies for autoimmune and infectious diseases, ... (USPTO) has issued an important new composition of ... function through the targeting of CLIP. ... peptide technology underlying VG Life Sciences, VG1177, a ...
(Date:3/2/2015)... Boston, Massachusetts (PRWEB) March 02, 2015 ... legal services, today announced the addition of Debbie Casey ... group’s capabilities in the healthcare space. , ... industry, most of which with Fresenius Medical Care North ... will leverage her extensive experience to work with Outside ...
(Date:2/27/2015)... 2015 Immunovaccine Inc. (“Immunovaccine” or the ... fraudulent press release disseminated this morning by PR Web, ... This press release states that Immunovaccine has entered into ... press release did not originate from Immunovaccine and there ... press release. Please note that all official statements ...
(Date:2/27/2015)... , Feb. 27, 2015 A paper ... NCATS rare-diseases portfolio " in Science Translational ... financing technique to reduce the risk associated with ... potentially unlock new levels of funding for developing ... of a unique collaboration between scientists at the ...
Breaking Biology Technology:VG Life Sciences Granted Key Composition Of Matter Patent 2VG Life Sciences Granted Key Composition Of Matter Patent 3Outside GC Expands Healthcare Team 2Immunovaccine Disclaims Hoax Press Release 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 4
... by 75 percent, SANTA CRUZ, Calif., Aug. 26 ... clinical communities of its member,schools in finding the "perfect ... listing fee reduction., An online job board and ... http://www.biocareercenter.com ) has,dropped its fee to $50 per academic ...
... -, MONTVALE, N.J., Aug. 26 Memory,Pharmaceuticals Corp. ... secured,$2.0 million through the sale of approximately 4.7 million ... June 2007 equity financing agreement,with an investment group led ... its option to complete the third,and final tranche following ...
... (Nasdaq: TPTX ) today announced that it received ... 21, 2008., The notice, in accordance with NASDAQ ... company,s common stock has,closed below $1.00 per share for ... on the NASDAQ listing or trading of,the company,s common ...
Cached Biology Technology:Online Career Site Assists Academia in Its Reach 2Memory Pharmaceuticals Closes Final Tranche of Equity Financing with The Stanley Medical Research Institute 2Memory Pharmaceuticals Closes Final Tranche of Equity Financing with The Stanley Medical Research Institute 3TorreyPines Therapeutics Receives NASDAQ Deficiency Notice 2
Mouse polyclonal antibody to QPRT - quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))...
... PCR Optimization Kits with ammonium sulfate are ... PCR, such as Tfl, Tth, and Pfu ... performance of PCR systems in one experiment ... PCR primers into the PreMixes supplied with ...
... meet the needs of the ... medium supports fast cell growth ... while maintaining high cell viability ... using the Baculovirus Expression Vector ...
... IPL-41 is part of a series of media ... by Weiss et al. for the large scale ... The medium is primarily used for the growth ... and the propagation of viruses in these cell ...
Biology Products: