Navigation Links
Metal ions regulate terpenoid metabolism in insects
Date:2/28/2013

Sequence comparisons cannot replace a thorough biochemical analysis

How the different metal ions modify the product range of the enzyme is still unclear. It is very likely that the varying atomic radii of the metal ions involved in the catalysis effect changes in the spatial structure of the enzyme, which prevent or allow the admission of a third C5 unit and hence result in the production of C10 or C15 molecules.

"Our experiments provide two important findings," says Wilhelm Boland, director at the Max Planck Institute. "First, the directing influence of metal ions on the product formation of isoprenyl diphosphate synthases is a novel "control element" in the regulation of the terpene metabolism which should be included in future experimental settings. And secondly: The diversity of terpenoid molecules cannot be attributed solely to the broad substrate specificity of some enzymes in the last steps of the metabolic pathway, but is in fact already inherent in early biosynthetic steps." Nature continues to provide interesting answers to the question how organisms manage to produce tens of thousands of different secondary metabolites. [JWK/AO]


'/>"/>

Contact: Antje Burse
aburse@ice.mpg.de
49-364-157-1265
Max Planck Institute for Chemical Ecology
Source:Eurekalert  

0

GOOD

Page: 1 2 3

Related biology news :

1. A new avenue to better medicines: Metal-peptide complexes
2. Earthworms soak up heavy metal
3. Nano-velcro clasps heavy metal molecules in its grips
4. Increase in metal concentrations in Rocky Mountain watershed tied to warming temperatures
5. Measuring mercury levels: Nano-velcro detects water-borne toxic metals
6. Sweet new approach discovered to help produce metal casting parts, reduce toxicity
7. SETAC announces Chris Lee Award for metals research winner, Kevin Brix
8. Onion soaks up heavy metal
9. Bluemetal Architects appoints David Le Penske as Vice President of Health & Life Sciences
10. Law that regulates shark fishery is too liberal: UBC study
11. Gut microbiota regulates bile acid metabolism
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Metal ions regulate terpenoid metabolism in insects
(Date:5/21/2013)... a class of pharmaceuticals can both prevent and treat ... as "TSPO ligands," are currently used for certain types ... TSPO ligand in young adult mice when pathology was ... pathology was quite severe," said lead researcher Christian Pike ... reduced measures of pathology and improved behavior at both ...
(Date:5/21/2013)... Mo. Cancers of all types become most deadly ... Once cancer has reached this stage, it becomes very ... tumors that can develop. Now, researchers at the University ... nanoparticles that target lymphoma tumor cells wherever they may ... of oncology in the MU College of Veterinary Medicine, ...
(Date:5/21/2013)... stores, phosphatidylserine is a natural food supplement produced ... cognition and slow memory loss, it,s a popular ... a team headed by Prof. Gil Ast and ... of Human Molecular Genetics have discovered ... genes involved in degenerative brain disorders, including Parkinson,s ...
Breaking Biology News(10 mins):Drugs found to both prevent and treat Alzheimer's disease in mice 2MU researchers develop radioactive nanoparticles that target cancer cells 2Common food supplement fights degenerative brain disorders 2
... iris recognition and DNA databases, but researchers in India ... allow law enforcement agencies and airport security to recognize ... gait. The team reveals details of a comprehensive framework ... of the Inderscience publication, the International Journal of ...
... same time impact the delivery of drugs and explain ... synthetic nanoparticles that can penetrate a cell without poking ... The key to their approach? Stripes. The ... of two different kinds of molecules can quickly pass ...
... The appointment of James Watson as Director ... an explosive development of research at Cold Spring Harbor ... of investigators with diverse scientific interests. In a ... scientists involved tell the stories of research carried out ...
Cached Biology News:Tell me by the way I walk 2MIT: Stripes key to nanoparticle drug delivery 2Watson-inspired innovation in research at Cold Spring Harbor Laboratory 2
(Date:5/21/2013)... Through science fairs, workshops, kits for building optical ... organizations will continue their work to increase awareness about ... daily life with the aid of SPIE Education ... countries, are the first of two groups of recipients ... international society for optics and photonics , in 2013. ...
(Date:5/21/2013)... Raleigh, NC (PRWEB) May 21, 2013 ... and financial services company for clinical trials, announced ... Aggregate Spend Solutions, LLC. Clinverse’s ClinPay® FLS ... automated investigator payment process. SpendMD ™, ... only complete solution for tracking and reporting transfer ...
(Date:5/21/2013)... (PRWEB) May 21, 2013 Emerson ... announced that Dr. Charles Signorino, the Company’s Chief Executive ... 1, 2013 after 32 years of service. As part ... Emerson’s current President, has been named as Dr. Signorino’s ... in the pharmaceutical industry, having made a significant contribution ...
(Date:5/21/2013)... MN (PRWEB) May 21, 2013 Revolutionary ... patented automatic colony counter, announced today that they have ... products , the IncuCount, IntelliCount, InCount and ImpressCount. ... and sophistication are especially useful in food microbiology and ... given an updated look. A bright white enclosure ...
Breaking Biology Technology:Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 2Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 3Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3Emerson Resources Announces CEO Retirement and Appointment of Successor 2Emerson Resources Announces CEO Retirement and Appointment of Successor 3Revolutionary Science Announces New Automatic and Manual Colony Counting Products 2
... New research suggests that some patients develop a potentially ... bacterial cells in their bodies have gene mutations that ... with implants can develop infections because of a biofilm ... devices. Researchers found that some strains of the bacteria, ...
... electronic and mechanical effects occurring in devices and ... are being investigated by researchers around the world. ... the generation of light, optical sensing, and information ... in physics and applications in this area, the ...
... (Nasdaq: CELG: $68) has been picked by S&P Capital ... carries S&P Capital IQ,s highest investment recommendation of 5-STARS, ... be among the best positioned biotechs for long-term growth, ... Equity Analyst at S&P Capital IQ.  "We believe the ...
Cached Biology Technology:Study offers clues as to why some patients get infections from cardiac implants 2Study offers clues as to why some patients get infections from cardiac implants 3Study offers clues as to why some patients get infections from cardiac implants 4Study offers clues as to why some patients get infections from cardiac implants 5Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 2Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 3Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 4Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 5S&P Capital IQ Picks Celgene Focus Stock of the Week 2S&P Capital IQ Picks Celgene Focus Stock of the Week 3
Rabbit polyclonal to FANCG ( Abpromise for all tested applications). Antigen: Synthetic peptide: MSRQTTSVGSSC, corresponding to amino acids 1 - 12 of Human FANCG. Entrez GeneID: 2189 Swis...
Rabbit polyclonal to DcR2 ( Abpromise for all tested applications). entrezGeneID: 8793 SwissProtID: Q9UBN6...
...
...
Biology Products: