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Metal in the heart is non-hazardous to health
Date:2/18/2014

imal invasive surgery," Dr. Undisz says. Ideally the implant will stay in the patient's body for years or decades.

Dr. Undisz and the doctoral candidate Katharina Freiberg wanted to find out what happens during this period of time with the nickel-titanium wire. They exposed samples of the wires, which underwent different mechanical and thermal pre-treatment, to highly purified water. They then examined the release of nickel according to pre-defined time intervals. "This wasn't trivial at all", Undisz says, "because the concentration of the released metal is often at the limit of detection." However, in co-operation with scientists from the Institute for Clinical Chemistry and Laboratory Medicine of the Jena University Hospital the materials scientists successfully developed a reliable test routine to measure the process of the nickel release.

"Mostly in the first days and weeks, depending on the pre-treatment of the material, considerable amounts of nickel may get released," Undisz summarizes the results. According to the materials scientist this is due to the mechanical strain of the implant during the surgery. "The deformation damages the thin layer of oxide covering the material. As a consequence the initial nickel release increases." In the long run, however, the nickel release decreases to amounts of a few nanograms per day and is hence far below the amount of nickel that we absorb anyway through our food on a daily basis.


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Contact: Ute Schoenfelder
presse@uni-jena.de
Friedrich-Schiller-Universitaet Jena
Source:Eurekalert  

Page: 1 2

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