Navigation Links
Metagenomics of skin reveals insights into the human microbiome
Date:5/22/2008

Friday, May 23, 2008 The human body is home to a diverse range of microorganisms, estimated to outnumber human cells in a healthy adult by ten fold. The importance of characterizing human microbiota for understanding health and disease is highlighted by the recent launch of the Human Microbiome Project by the National Institutes of Health. This report, published online today in Genome Research (www.genome.org), describes the investigation of healthy human skin for microbiota diversity and establishes the basis for determining a core microbiome.

The Human Microbiome Project aims to characterize the microbial communities of several regions of the body, including skin, where determining the core microbiome is essential to understanding and developing new treatments for skin conditions and diseases such as acne and atopic dermatitis (eczema). In this study, researchers led by Dr. Julie Segre of the National Human Genome Research Institute have generated a diversity profile of human skin microbiota by sequencing 16S rRNA, a component of the prokaryotic ribosome, isolated from a specific region of skin. We focused this study on the inner elbow to inform future clinical studies of the extremely common inflammatory skin disorder atopic dermatitis, which affects this area of the skin and is associated with Staphylococcus infections, explains Segre.

The researchers find that in the healthy subjects tested, Proteobacteria (predominantly Pseudomonas and Janthinobacterium) constituted the majority of inner elbow microbiota. Furthermore, this survey indicated that a common core skin microbiome exists between these individuals. Segre adds that this finding is critical for studying disease. Our long-term goal is to clarify the microbial contribution to a myriad of skin disorders both with known and suspected bacterial infections. Segres group also found that the microbiota of mous
'/>"/>

Contact: Peggy Calicchia
calicchi@cshl.edu
516-422-4012
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Metagenomics of the deep Mediterranean
2. Metagenomics of the deep Mediterranean
3. A study reveals how cells communicate to activate the cell division machinery
4. Lean and mean biomass-degrading fungus reveals capabilities for improved biofuel production
5. First nanoscale image of soil reveals an incredible variety, rich with patterns
6. Power of molecular imaging reveals secrets of the heart
7. Isotope analysis reveals foraging area dichotomy for Atlantic leatherback turtles
8. Smithsonians National Museum of Natural History reveals ants as fungus farmers
9. Mantis shrimp vision reveals new way that animals can see
10. Research at Argonnes Advanced Photon Source reveals structure and behavior of collagen
11. New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... There is evidence that under the normal ... and development, maintain neuronal environment, and exhibit ... and neurodegenerative disease. Previous studies have found ... cells after chemical induction have reduced viability, ... application. Prof. Xiaodong Yuan, Kailuan General Hospital, ...
(Date:7/11/2014)... that let nerve cells send out electrical signals, Johns ... tactic that may offer a new way to protect ... responsible way. , Their findingthat naturally occurring insect ... for a closely related onesuggests that insecticides can be ... like bees. A summary of the research, led by ...
(Date:7/10/2014)... 27, 2014  The American Academy of Forensic ... Standards and Technology (NIST) and the Department of ... and forensic science expert members to the Forensic ... element of the NIST,s Organization of Scientific Area ... first appointments made to the new FSSB that ...
Breaking Biology News(10 mins):Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3
... we,ve been told, eliminating or severely limiting fats from ... in patients suffering from heart failure, a study at ... Results from biological model studies conducted by assistant professor ... researchers, demonstrate that a high-fat diet improved overall mechanical ...
... WASHINGTON The Chesapeake Bay Program is a ... jurisdictions in the bay watershed to oversee the restoration ... the extent of pollutants -- such as nitrogen, phosphorus, ... from the National Research Council assesses the framework used ...
... a researcher at the Royal Swedish Academy of Sciences, Margareta ... permafrost. "The changes we see are dramatic. And ... from the norm when compared with a longer term perspective", ... of the globe that is warming up fastest today. Measurements ...
Cached Biology News:Damaged hearts pump better when fueled with fats 2Chesapeake Bay program's 2-year milestones improve upon past strategies, but accounting of progress remains a challenge 2A new research report shows effects of climate change in the Arctic are more extensive than expected 2A new research report shows effects of climate change in the Arctic are more extensive than expected 3
(Date:7/10/2014)... 2014 Product and process impurities ... abundance and are often “lost in the noise,” ... Join presenters Dr. Rowel Tobias, Senior Scientist, Protein ... Head of Quality at Nanotherapeutics, Inc., to lear ... speed detection and quantitation while achieving the required ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Terascala, the ... announced that Alan Swahn, a former vice president of ... team as vice president of marketing. Terascala’s software when ... and NetApp create the highest performance and most reliable ... appointed to guide Terascala’s channel expansion and broaden its ...
(Date:7/10/2014)... OMICS Group’s 5th International conference and exhibition ... at Double Tree by Hilton Beijing, China is all ... & Bioanalytical research methods only to facilitate improved living ... Dr. Srinubabu Gedela, MD of OMICS Group Inc has ... one in bringing a unique and international mix of ...
(Date:7/10/2014)... , July 10, 2014  Franciscan ... use of capnography for respiratory monitoring outside ... of healthcare leaders in embracing state-of-the-art patient ... effectively patients are breathing and can alert ... By measuring the amount of carbon dioxide ...
Breaking Biology Technology:Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2
... has succeeded in significantly increasing the sensitivity of the ... on this topic at Delft University of Technology on ... and astronomers from around the world are currently working ... of 66 advanced telescopes which will be placed at ...
... Iceland, February 3 deCODE genetics,(Nasdaq: DCGN ) ... letter from,the Nasdaq Listing Qualifications Panel (the "Panel") stating ... stock from the Nasdaq Global,Market to the Nasdaq Capital ... Wednesday, February 4, 2009. The Nasdaq Capital Market, which ...
... DHA (docosahexaenoic acid) omega-3 innovator and maker of the ... today that it has entered into a license agreement ... is a process widely used in food manufacturing that ... the nutritional value, shelf-life and flavor of the finished ...
Cached Biology Technology:Nanotechnology makes supertelescopes much more sensitive 2deCODE Announces Transfer of the Listing of its Common Stock from Nasdaq Global Market to Nasdaq Capital Market 2deCODE Announces Transfer of the Listing of its Common Stock from Nasdaq Global Market to Nasdaq Capital Market 3Martek, General Mills Collaborate on Microencapsulation Technology for Food Applications 2Martek, General Mills Collaborate on Microencapsulation Technology for Food Applications 3
Features , Designed to assist users in applying domed caps to tube strips and plates , Minimises the pressure required to seal the caps effectively , Enables multiple tubes to be sealed simultaneousl...
Lysozyme C (W-20)...
... ventilated and BR4i refrigerated multifunction centrifuges are equally ... at a low sound level with a large ... Their AUTO-LOCK rotor exchange system without tools ensures ... within seconds. Instant rotor exchange (5 ...
... X-Gal (5-bromo-4-chloro-3-indoyl-beta-D-galactopyranoside) is a ... identify recombinant plasmids. In ... and IPTG, lac ... blue, whereas recombinant colonies ...
Biology Products: