Navigation Links
Meta-analysis: Radiotherapy variants improve survival in non-metastatic lung cancer
Date:4/30/2010

A new meta-analysis reported at the second European Lung Cancer Conference shows that patients with both non-small-cell lung cancer and small-cell lung cancer benefit in terms of overall survival when treated with hyperfractionated or accelerated radiotherapy.

Patients treated with hyperfractionated or accelerated radiotherapy regimens are given their treatments more frequently, and over a shorter period of time. The benefit of doing this has been in question as different randomized trials have given contradictory results.

Dr Cecile Le Pechoux and colleagues from Institut Gustave Roussy in Villejuif, France analyzed 10 trials including 2,279 patients with non-metastatic lung cancer. They found that in the eight trials dealing with non-small-cell lung cancer, modified fractionation of the radiotherapy improved overall survival compared to conventional radiotherapy, resulting in an absolute benefit of 3% after 5 years, meaning that 3% more of the patients were alive after 5 years in the modified fractionation groups.

"The clinical benefit we found was small, but comparable to the benefit found in other meta-analyses concerning non-small-cell lung cancer," Dr Le Pechoux said.

Lung cancer remains a major cause of death worldwide with more than 1.1 million deaths per year. Non-small-cell lung cancer (NSCLC) represents more than 80% of all lung tumors and small-cell lung cancer (SCLC) less than 20%. Approximately 35% of patients with NSCLC, and less than a third of SLSC patients, present with locally advanced, non-metastatic disease. The standard treatment for these patients is combined radio-chemotherapy.

In small-cell lung cancer, which is a less common form of the disease, similar results were found, although the difference in survival between the standard and modified radiotherapy regimens was not statistically significant because of lack of power.

These results could encourage further work to determine how
'/>"/>

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

Page: 1 2

Related biology news :

1. 4-D software helps adjust for breathing when treating lung cancer with radiotherapy
2. Tool allows precise targeting of radiotherapy for cancer radiation therapy
3. Concord Medical Enters Agreement to Acquire Four Radiotherapy and Diagnostic Imaging Centers in Hebei Province
4. Specific lymph node radiotherapy is well-tolerated after surgery in early breast cancer patients
5. Breakthrough in radiotherapy promises targeted cancer treatment
6. Two-day symposium in Baltimore to tackle the promises and perils of proton radiotherapy
7. New gene variants associated with glucose, insulin levels, some with diabetes risk
8. Identification of genetic variants affecting age at menopause could help improve fertility treatment
9. Common gene variants influence risk factor for sudden cardiac death
10. Common gene variants increase risk of hypertension, may lead to new therapies
11. International study identifies gene variants associated with early heart attack
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a ... announced that its DigitalPersona ® Pro Enterprise ... have been deployed throughout First Bank branch locations ... South Carolina and Virginia. First Bank, ... Southern Pines, North Carolina , selected ...
(Date:11/21/2014)... MOUNTAIN VIEW, Calif. , Nov. 20, 2014 /PRNewswire/ ... for higher driver efficiency are piloting the North American ... the number of accidents growing, gesture recognition systems that ... will make a mark in the industry. ... of the Automotive Gesture Recognition Market in ...
(Date:11/18/2014)... BETHESDA, Md. , Nov. 17, 2014 The ... European and U.S. regulatory agencies will speak and at least ... Quality Metrics Conference at the Omni Shoreham Hotel in ... is pleased once again to have significant support from the ... and Europe in our effort to ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 2Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 4FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... press release is available in French . ... Laval researchers and their colleagues from the Canadian Forest Service ... and fir has remained very much the same for over ... between today,s conifers and fossils dating back to the days ...
... Rochelle, NY, December 13A leading scientific society of university ... research in the sciences and technologies of environmental protection, ... (AEESP) , has selected the peer-reviewed journal ... Environmental Engineering Science is read around the ...
... animal cell is like a small city, with factoriescalled ... life functions. A network of intercellular "highways," called microtubules, ... speedily about the cell to keep this vital machinery ... Proceedings of the National Academy of Sciences ...
Cached Biology News:Your Christmas tree and its genome have remained very much the same over the last 100 million years 2Association of Environmental Engineering and Science Professors name Environmental Engineering Science as its official journal 2Study sheds light on how cells transport materials along crowded intercellular 'highways' 2Study sheds light on how cells transport materials along crowded intercellular 'highways' 3
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... - Mercedes Walton, Chairman and CEO of Cryo-Cell International ... Fla., March 17 As the CEO of Cryo-Cell ... bank, Mercedes Walton has been an active participant in ... She has seen first-hand the changes that have taken ...
... Spiral Biotech, an Advanced Instruments company, will ... -- which delivers faster cycle times, a ... processing speed and efficiency in microbiology laboratories -- ... Meeting in May, 2009."The introduction of the new ...
... Ferring Pharmaceuticals Inc., a specialty pharmaceutical company, ... to Senior Vice President of the Ferring International ... for Ferring Pharmaceuticals Inc. Dr. Korner was ... Orthopaedics, Urology, and Gastroenterology therapeutic areas, as well ...
Cached Biology Technology:Stem Cell Industry Insider Mercedes Walton Discusses President Obama's Stem Cell Executive Order 2Stem Cell Industry Insider Mercedes Walton Discusses President Obama's Stem Cell Executive Order 3Spiral Biotech to Introduce New Autoplate Spiral Plating System at ASM General Meeting in May 2Spiral Biotech to Introduce New Autoplate Spiral Plating System at ASM General Meeting in May 3Dr. Paul Korner Promoted to Senior Vice President of Ferring International PharmaScience Center U.S. 2
...
Whole blood is collected from healthy guinea pigs of either sex from US source which are free of visible diseases at time of blood collection. Hemolytic titer: CH50 = 435 units...
... l-[35S]in vitro cell labeling mix, ... *Aqueous solution stabilized with 0.1% ... pyridine 3,4-dicarboxylic acid. *Amino acid ... labeling containing l-[35S]Methionine and l-[35S]Cysteine. ...
...
Biology Products: