Navigation Links
'Memory molecule' stores memories in neocortex
Date:8/16/2007

The memory storage molecule PKMzeta maintains long-term memories in the neocortex and its presence is continually required in order for the memory to endure, according to a finding by researchers at the Weizmann Institute in Rehovot, Israel and SUNY Downstate Medical Center in Brooklyn, New York. The study results were published in the current edition of Science magazine (www.sciencemag.org). The title of the paper is Rapid Erasure of Long-Term Memory Associations in Cortex by an Inhibitor of PKMzeta.

It was previously determined that PKMzeta in the hippocampus an area of the brain involved in navigation and the initial storage of memory was necessary to preserve spatial memory; but little was known about PKMzeta activity in the neocortex, the part of the brain thought to be responsible for permanently storing most long-term memories, including those required for higher-level cognitive functions, such as language and complex thought.

This new finding that inhibiting PKMzeta causes the rapid loss of neocortical memories learned even weeks before means that persistent phosphorylation by PKMzeta in the neocortex is necessary to store these long-term memories and has potential clinical significance, for example, in the field of cognitive enhancement.


'/>"/>

Contact: Todd C. Sacktor
todd.sacktor@downstate.edu
718-270-3933
SUNY Downstate Medical Center
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers Uncover Key Step In Manufacture of Memory Protein
2. Nanogen Issued Patent for Electronic Microarray With Memory
3. Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
4. Structure-building cell signals also may influence learning and memory
5. Mice brains shrink during winter, impairing some learning and memory
6. Montreal researchers probe the genetic basis of memory
7. New research shows why too much memory may be a bad thing
8. U of MN researchers reverse memory loss in mice
9. Researchers know what you were about to say; fMRI used to detect memory storage and retrieval
10. Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace
11. Tracking the memory trace
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/26/2020)... ... August 25, 2020 , ... Mitotech ... partnership with Essex Bio-Technology, a bio-pharmaceutical company specializing in Ophthalmology and Dermatology, ... of SkQ1 ophthalmic solution in patients with moderate to severe Dry Eye ...
(Date:8/26/2020)... ... ... Modality Solutions, a biopharmaceutical cold chain validation engineering firm, is ... is the most prestigious ranking of the nation’s fastest-growing private companies. Modality Solutions made ... three-year revenue growth of 71 percent. , The Inc. 5000 list represents a ...
(Date:8/21/2020)... Mass. (PRWEB) , ... August 18, 2020 , ... ... approaches to cell therapy, today announced that the U.S. Food and Drug Administration ... of Sentien’s lead asset, SBI-101, for the treatment of severe COVID-19. Approval of ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... ... August 11, 2020 , ... ... is making available for free its new white paper – Simulated Transport ... testing into today’s biologics licensing application (BLA). In response, Modality Solutions shares ...
(Date:8/7/2020)... , ... August 06, 2020 , ... ... vaccine industries, announces it has closed on the purchase of greenfield for a ... Conroe, TX and includes over 21 acres in the initial acquisition, with an ...
(Date:8/3/2020)... , ... August 03, 2020 , ... Introducing Ardent Animal ... transformative growth, , Known as MediVet Biologics since its formation ... The new Ardent Animal Health will build on its base of innovative ...
(Date:7/31/2020)... ... July 29, 2020 , ... G-CON ... of its new tagline, “BUILDING FOR LIFE.” The adoption of this taglines comes ... globe, requiring fast track capacity to provide patients with urgently needed vaccines and ...
Breaking Biology Technology: