Navigation Links
'Memory molecule' stores memories in neocortex
Date:8/16/2007

The memory storage molecule PKMzeta maintains long-term memories in the neocortex and its presence is continually required in order for the memory to endure, according to a finding by researchers at the Weizmann Institute in Rehovot, Israel and SUNY Downstate Medical Center in Brooklyn, New York. The study results were published in the current edition of Science magazine (www.sciencemag.org). The title of the paper is Rapid Erasure of Long-Term Memory Associations in Cortex by an Inhibitor of PKMzeta.

It was previously determined that PKMzeta in the hippocampus an area of the brain involved in navigation and the initial storage of memory was necessary to preserve spatial memory; but little was known about PKMzeta activity in the neocortex, the part of the brain thought to be responsible for permanently storing most long-term memories, including those required for higher-level cognitive functions, such as language and complex thought.

This new finding that inhibiting PKMzeta causes the rapid loss of neocortical memories learned even weeks before means that persistent phosphorylation by PKMzeta in the neocortex is necessary to store these long-term memories and has potential clinical significance, for example, in the field of cognitive enhancement.


'/>"/>

Contact: Todd C. Sacktor
todd.sacktor@downstate.edu
718-270-3933
SUNY Downstate Medical Center
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers Uncover Key Step In Manufacture of Memory Protein
2. Nanogen Issued Patent for Electronic Microarray With Memory
3. Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
4. Structure-building cell signals also may influence learning and memory
5. Mice brains shrink during winter, impairing some learning and memory
6. Montreal researchers probe the genetic basis of memory
7. New research shows why too much memory may be a bad thing
8. U of MN researchers reverse memory loss in mice
9. Researchers know what you were about to say; fMRI used to detect memory storage and retrieval
10. Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace
11. Tracking the memory trace
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... leader in attendance control systems is proud to announce the introduction of fingerprint attendance ... the right employees are actually signing in, and to even control the opening of ... ... ... Photo - ...
(Date:6/3/2016)... , June 3, 2016 ... Management) von Nepal ... und Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, ... führend in der Produktion und Implementierung von ... der Ausschreibung im Januar teilgenommen, aber Decatur ...
(Date:6/2/2016)... -- Perimeter Surveillance & Detection Systems, Biometrics ... Support & Other Service  The latest report ... analysis of the global Border Security market . ... $17.98 billion in 2016. Now: In November ... software and hardware technologies for advanced video surveillance. ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... ... to announce the launch of their brand, UP4™ Probiotics, into Target stores nationwide. ... years, is proud to add Target to its list of well-respected retailers. This ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the ... at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application ... team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our ...
(Date:6/23/2016)... 23, 2016 On Wednesday, June 22, ... down 0.22%; the Dow Jones Industrial Average edged 0.27% lower ... 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on the following ... Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ... BIND ). Learn more about these stocks by accessing ...
Breaking Biology Technology: