Navigation Links
'Memory molecule' stores memories in neocortex
Date:8/16/2007

The memory storage molecule PKMzeta maintains long-term memories in the neocortex and its presence is continually required in order for the memory to endure, according to a finding by researchers at the Weizmann Institute in Rehovot, Israel and SUNY Downstate Medical Center in Brooklyn, New York. The study results were published in the current edition of Science magazine (www.sciencemag.org). The title of the paper is Rapid Erasure of Long-Term Memory Associations in Cortex by an Inhibitor of PKMzeta.

It was previously determined that PKMzeta in the hippocampus an area of the brain involved in navigation and the initial storage of memory was necessary to preserve spatial memory; but little was known about PKMzeta activity in the neocortex, the part of the brain thought to be responsible for permanently storing most long-term memories, including those required for higher-level cognitive functions, such as language and complex thought.

This new finding that inhibiting PKMzeta causes the rapid loss of neocortical memories learned even weeks before means that persistent phosphorylation by PKMzeta in the neocortex is necessary to store these long-term memories and has potential clinical significance, for example, in the field of cognitive enhancement.


'/>"/>

Contact: Todd C. Sacktor
todd.sacktor@downstate.edu
718-270-3933
SUNY Downstate Medical Center
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers Uncover Key Step In Manufacture of Memory Protein
2. Nanogen Issued Patent for Electronic Microarray With Memory
3. Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
4. Structure-building cell signals also may influence learning and memory
5. Mice brains shrink during winter, impairing some learning and memory
6. Montreal researchers probe the genetic basis of memory
7. New research shows why too much memory may be a bad thing
8. U of MN researchers reverse memory loss in mice
9. Researchers know what you were about to say; fMRI used to detect memory storage and retrieval
10. Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace
11. Tracking the memory trace
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... March 27, 2017  Catholic Health Services (CHS) ... Systems Society (HIMSS) Analytics for achieving Stage 6 ... sm . In addition, CHS previously earned a ... using an electronic medical record (EMR). ... level of EMR usage in an outpatient setting.  ...
(Date:3/24/2017)... MILAN , March 24, 2017 The Controller ... Deputy Controller Mr. Abdulla Algeen have received the prestigious international ... Continue Reading ... ... small picture) and Deputy Controller Abdulla Algeen (small picture on the right) ...
(Date:3/24/2017)... -- Research and Markets has announced the addition of ... - Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle ... around 15.1% over the next decade to reach approximately $1,580 million ... estimates and forecasts for all the given segments on global as ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... , March 27, 2017 DarioHealth Corp. (NASDAQ: ... health and big data solutions, today announced that it ... coverage option for U.S. consumers who want to have ... DarioHealth has signed strategic alliance agreements with partners across ... coverage benefits, and if approved, will supply and bill ...
(Date:3/24/2017)... MARIETTA, Ga. , March 24, 2017 ... and biopharmaceutical company utilizing human placental tissue allografts and ... therapies for multiple sectors of healthcare, announced today  that ... New York , NY.  Parker H. ... , Chief Financial Officer, Christopher M. Cashman , ...
(Date:3/24/2017)... Research and Markets has announced the addition ... Strategic Business Report" report to their offering. ... This report analyzes the Global ... Annual estimates and forecasts are provided for the period 2014 through ... research. The report profiles 25 companies including many ...
(Date:3/24/2017)... , March 24, 2017 On ... trading session at 5,817.69, down 0.07%; the Dow Jones ... and the S&P 500 closed at 2,345.96, marginally dropping ... sectors closed in green, 4 sectors finished in red, ... Friday, Stock-Callers.com has initiated reports coverage on the following ...
Breaking Biology Technology: