Navigation Links
Meet Phannie, NIST's standard 'phantom' for calibrating MRI machines
Date:5/12/2010

Magnetic resonance imaging (MRI)a widely used medical tool that relies on magnetic fields and radio waves to visualize the body's internal structures, especially soft tissuesmay soon become even more useful.

The National Institute of Standards and Technology (NIST) has unveiled the first "phantom" for calibrating MRI machines that is traceable to standardized values. The prototype, named Phannie, was developed in collaboration with the standards committee of the International Society for Magnetic Resonance in Medicine (ISMRM).

Traceable MRI calibrations are expected to enable accurate, quantitative measurements of tumors and other disease markers that can be reproduced across many different patients, scanners and clinics over timeand potentially reduce medical costs.

Displayed at the annual ISMRM meeting this past week,* the NIST phantom is a plastic sphere about the size of a person's head, filled with water-bathed grids of 100 small plastic spheres containing various salt solutions that become magnetized in a magnetic field. By making MRI scans of Phannie, users can evaluate the image contrast, resolution, and accuracy of distance and volume measurements. A machine's performance can be compared to standards, to other MRI machines, and to itself over time.

MRI scanner performance may drift, or different machines may produce different images of the same patient. The new phantom is intended to help generate more accurate and consistent images, help validate disease mechanisms and treatments, and reduce medical costs by improving image quality and reliability. The phantom will assist multisite clinical trials that use quantitative MRI to test the efficacy of novel drugs.

A number of specialized MRI phantoms already exist; the need for new ones to support quantitative studies was recognized at a NIST workshop in 2006.** NIST's is the first phantom designed to ensure that MRI system properties and image data are traceable to international system of units (SI) standards. The ISMRM Ad Hoc Committee on Standards for Quantitative MR defined the phantom requirements and values. NIST modeled and built the prototype device and assured the accuracy of measured quantities. NIST also developed and tested various solutions used in the mini-spheres as contrast-enhancing agents and measurement reference markers. Phannie will now undergo testing at other institutions for about four months.

Stephen Russek, the physicist leading NIST's part of the project, says the phantom is intended to be not only accurate and traceable but also physically stable and affordable, so that it can become as widely used in MRI machines as seatbelts are in cars. He demonstrated the durability of the mini-spheres by bouncing one on the floor. Materials for Phannie cost $10,000, but hopefully, in mass production the cost per phantom can be reduced to $2,000, he says.

"If it's accurate, reliable and affordable, then you have a way to measure the accuracy of MRI scanners all across the country," Russek says. "If used routinely, it will allow us to get a complete snapshot of the quality and consistency of scanning."


'/>"/>

Contact: Laura Ost
laura.ost@nist.gov
303-497-4880
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Related biology news :

1. UF botanists: Flowering plants evolved very quickly into 5 groups
2. For the birds or for me? Why do conservationists really help wildlife?
3. Nutritionists of the UGR suggest diet improvements during Ramadan
4. Conservationists seek to identify prime stopover sites for migrating birds
5. Top interventional radiologists, neurointerventionists explore stroke care through CLOTS
6. Minimum information standards -- all for 1 and 1 for all
7. CO2 emissions could violate EPA ocean-quality standards within decades
8. Positron emission tomography superior to standard evaluation tools in measuring treatment response
9. NIST, Army researchers pave the way for anthrax spore standards
10. Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors
11. UC Riverside to host conference on stricter air quality standards for Southern California
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Meet Phannie, NIST's standard 'phantom' for calibrating MRI machines
(Date:12/2/2016)... , December 1, 2016 ... type (Fingerprint, Voice), Future Technology (Iris Recognition System), ... Region - Global Forecast to 2021", published by ... 442.7 Million in 2016, and is projected to ... a CAGR of 14.06%.      (Logo: ...
(Date:11/30/2016)... and WARSAW, Poland , Nov. 30, 2016 Not many ... of the most crucial aspects of recovery so we need to do it well. ... risks, including heart problems, high blood pressure, stroke, diabetes, and even cancer. ... and find a Christmas present that could help them to manage their sleep quality? ... ...
(Date:11/29/2016)... BioDirection, a privately held medical device company ... detection of concussion and other traumatic brain injury (TBI), ... meeting with the U.S. Food and Drug Administration (FDA) ... During the meeting company representatives reviewed plans for clinical ... commencement of a planned pilot trial. ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... , December 8, 2016 The report "Acrylic Processing Aid Market by ... Packaging, Automotive, Consumer Goods) - Global Forecast to 2026", published by MarketsandMarkets, the ... reach USD 1,173.6 Million by 2026, registering an of CAGR of 6.2% between ... ... MarketsandMarkets Logo ...
(Date:12/7/2016)... ANN ARBOR, Mich. , Dec. 7, ... developing breakthrough immune modulatory medicines, announced today the initiation ... lead therapeutic candidate, LYC-30937- E nteric C oated, ... skin disease that is estimated to affect as many ... , with approximately 1.5 - 3 million cases ...
(Date:12/7/2016)... ... December 07, 2016 , ... JULABO USA is ... cart. The new website has been designed to provide the best user-friendly experience ... to access detailed product information, read educational industry content as well as share ...
(Date:12/6/2016)... Dec. 6, 2016 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the "Company") ... the fourth quarter and fiscal year ended September 30, 2016. ... , , ... life sciences and diagnostics company that develops and commercializes proprietary technologies ... Achieved revenues of $1.4 million more than tripling ...
Breaking Biology Technology: