Navigation Links
Medical researchers make important research link between active ingredient in saffron and MS
Date:11/4/2011

Medical researchers at the University of Alberta have discovered that an active ingredient in the Persian spice saffron may be a potential treatment for diseases involving neuroinflammation, such as multiple sclerosis.

Chris Power and a team of researchers in the Faculty of Medicine & Dentistry recently published their findings in the peer-reviewed publication, The Journal of Immunology.

"We found there is a compound in saffron, known as crocin, that exerts a protective effect in brain cell cultures and other models of MS. It prevented damage to cells that make myelin in the brain," Power said. "Myelin is insulation around nerves. MS is characterized by inflamed brain cells that have lost this protective insulation, which ultimately leads to neurodegeneration."

Power noted they are not close to a clinical trial stage yet, but the finding is still exciting.

It has been known in the research community for years that crocin protected neurons in certain situations, but Power and his team wanted to delve further into this area.

His team discovered that inflammation and a specific type of cell stress are closely linked and lead to neurodegeneration and inflammation which cause cells to lose their protective coating a process known as demyelination. In experiments conducted by Power and his colleagues, the use of crocin suppressed both inflammation and this specific type of cell stress, resulting in decreased neurological impairment in lab models and cell cultures with MS.

"There are still many questions to be answered about how crocin exerts these neuroprotective effects, but this research highlights a potential treatment role for crocin in diseases involving chronic neuroinflammation something that had not been recognized until now," says Power.

He explained the research demonstrates a new mechanism in MS, provides new potential drug targets in the future, and helps explain why physicians s
'/>"/>

Contact: Raquel Maurier
raquel.maurier@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Page: 1 2

Related biology news :

1. Athens Regional Medical Center Upgrades to Omnicell G4 Platform for Supply and Medication Management
2. Manufacturing microscale medical devices for faster tissue engineering
3. Lung regeneration closer to reality with new discovery by Weill Cornell Medical College researchers
4. 21 Fellows inducted into American College of Medical Informatics
5. Researchers at NYU Langone Medical Center review the microbiome and its possible role in cancers
6. BioCrossroads Invests in Medical Device Company Developing Revolutionary Absorbable Stent
7. Cell biologist Chris A. Kaiser to lead NIHs National Institute of General Medical Sciences
8. Virginia Tech biomedical engineers announce child football helmet study
9. Genomic sequence and comparison of 2 macaques reveal new insights into biomedical research
10. Medical College of Wisconsin researchers show molecule inhibits metastasis
11. Organic medical imaging system to detect disease and track medication
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2015)... MINNETONKA, Minn. , Feb. 12, 2015 /PRNewswire/ ... technology company specializing in clinical study management systems, ... Partner Program , further distinguishing iMedNet ... for Clinical Research Organizations (CROs) and healthcare consultants.  ... sales support, prospective customer referrals and numerous co-marketing ...
(Date:2/10/2015)... 2015  Alere Inc. (NYSE: ALR), a global ... for the quarter ended December 31, 2014. ... of Alere said, "We made substantial progress in ... global leader in rapid diagnostics and delivering against ... divestiture in early January enabled us to substantially ...
(Date:2/5/2015)... PARK, N.C. , Feb. 5, 2015  Marken ... specialist logistics company and has launched a new marketing ... Clinical Logistics Organization (CLO).  The new campaign focuses on ... on patient, protocol and shipments. The first ... , aligns Marken,s priorities with its client,s priorities. ...
Breaking Biology News(10 mins):MedNet Solutions Announces Key Enhancements To Its iMedNet Partner Program 2Alere Inc. Announces Fourth Quarter 2014 Results 2Alere Inc. Announces Fourth Quarter 2014 Results 3Alere Inc. Announces Fourth Quarter 2014 Results 4Alere Inc. Announces Fourth Quarter 2014 Results 5Alere Inc. Announces Fourth Quarter 2014 Results 6Alere Inc. Announces Fourth Quarter 2014 Results 7Alere Inc. Announces Fourth Quarter 2014 Results 8Alere Inc. Announces Fourth Quarter 2014 Results 9Alere Inc. Announces Fourth Quarter 2014 Results 10Alere Inc. Announces Fourth Quarter 2014 Results 11Alere Inc. Announces Fourth Quarter 2014 Results 12Alere Inc. Announces Fourth Quarter 2014 Results 13Alere Inc. Announces Fourth Quarter 2014 Results 14Alere Inc. Announces Fourth Quarter 2014 Results 15Alere Inc. Announces Fourth Quarter 2014 Results 16Alere Inc. Announces Fourth Quarter 2014 Results 17Alere Inc. Announces Fourth Quarter 2014 Results 18Alere Inc. Announces Fourth Quarter 2014 Results 19Alere Inc. Announces Fourth Quarter 2014 Results 20Alere Inc. Announces Fourth Quarter 2014 Results 21Alere Inc. Announces Fourth Quarter 2014 Results 22Alere Inc. Announces Fourth Quarter 2014 Results 23Alere Inc. Announces Fourth Quarter 2014 Results 24Alere Inc. Announces Fourth Quarter 2014 Results 25Alere Inc. Announces Fourth Quarter 2014 Results 26Alere Inc. Announces Fourth Quarter 2014 Results 27Alere Inc. Announces Fourth Quarter 2014 Results 28Alere Inc. Announces Fourth Quarter 2014 Results 29Alere Inc. Announces Fourth Quarter 2014 Results 30Alere Inc. Announces Fourth Quarter 2014 Results 31Alere Inc. Announces Fourth Quarter 2014 Results 32Alere Inc. Announces Fourth Quarter 2014 Results 33Alere Inc. Announces Fourth Quarter 2014 Results 34Alere Inc. Announces Fourth Quarter 2014 Results 35
... State University researcher is exploring a new method of ... is more effective and reliable than using eye drops. ... clinical sciences at Iowa State,s College of Veterinary Medicine, ... method of implanting biodegradable medicine into the tissue surrounding ...
... mechanism has been discovered in a microorganism that thrives in ... key processes in human cells, and in a better understanding ... study is published today in the online version the American ... group at the Department of Molecular Evolution at Uppsala University ...
... chemicals, such as methylmercury can cause harm at levels ... evidence in the International Journal of Environment and ... approach to this and similar compounds to protect unborn ... the Department of Environmental Health at Harvard School of ...
Cached Biology News:Iowa State researcher develops new treatment method for canine eye diseases 2Iowa State researcher develops new treatment method for canine eye diseases 3New cell division mechanism discovered 2Methylmercury warning 2
(Date:3/4/2015)... VILLAGE, Nev. , March 4, 2015 PDL BioPharma, ... the adjusted conversion rate for the: , 3.75% ... is 174.8506 shares of common stock per $1,000 principal amount ... The conversion rate for the note is adjusted in ... paid on March 12, 2015, to all stockholders who own shares ...
(Date:3/4/2015)... BALTIMORE , March 4, 2015 The ... of its 2015 Fellows in the Emerging Leaders in ... fostering future leaders in the field of biosecurity, UPMC ... biosecurity from a wide array of backgrounds, including biological ... private sector. "With the vision and ...
(Date:3/4/2015)... SANTA BARBARA, CALIFORNIA (PRWEB) March 04, 2015 ... regulatory consulting firm in the life sciences industry, hired ... Compliance. Blewitt leads the Cloud Compliance Services and ... sciences companies utilize cloud based applications while maintaining compliance ... 20 years, Blewitt has been an accomplished life sciences ...
(Date:3/4/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/jspg2c/global_biologics ) ... Biologics and Biosimilars Industry Report 2015" report ... Global Biologics and Biosimilars Industry Report 2015 is ... state of the biologics and biosimilars industry. ... the industry including definitions, classifications, applications and industry ...
Breaking Biology Technology:PDL BioPharma Announces Conversion Rate Adjustment for Convertible Note 2UPMC Center for Health Security Announces 2015 Emerging Leaders in Biosecurity 2UPMC Center for Health Security Announces 2015 Emerging Leaders in Biosecurity 3USDM Life Sciences Names David Blewitt VP of Cloud Compliance for Regulated Life Sciences 2USDM Life Sciences Names David Blewitt VP of Cloud Compliance for Regulated Life Sciences 3Global Biologics and Biosimilars Industry Report 2015-2020 2
... This release is available in German . ... Science (CFEL) have built the world,s smallest magnetic data storage unit. ... information, and squeezes a whole byte (8 bit) into as few ... more than half a billion atoms per byte. The team present ...
... cell therapy manufacturing division, Progenitor Cell Therapy ("PCT"), ... NBS ) ("NeoStem" or the "Company"), announced today ... and regulatory services related to the development of ... injectable suspension of microencapsulated insulin-producing, pancreatic islet cells ...
... have imagined that the world would be seriously concerned over ... periodic table, dysprosium was once just another element for chemistry ... sought-after and critically needed materials on the planet. Belonging ... earths-dysprosium and other rare earths are used in almost every ...
Cached Biology Technology:The world's smallest magnetic data storage unit 2The world's smallest magnetic data storage unit 3Islet Sciences, Inc. Selects NeoStem's Manufacturing Subsidiary Progenitor Cell Therapy for Product Manufacturing 2Islet Sciences, Inc. Selects NeoStem's Manufacturing Subsidiary Progenitor Cell Therapy for Product Manufacturing 3Islet Sciences, Inc. Selects NeoStem's Manufacturing Subsidiary Progenitor Cell Therapy for Product Manufacturing 4Berkeley Lab seeks to help US assert scientific leadership in critical materials 2Berkeley Lab seeks to help US assert scientific leadership in critical materials 3Berkeley Lab seeks to help US assert scientific leadership in critical materials 4Berkeley Lab seeks to help US assert scientific leadership in critical materials 5
... Arrays are intended for laboratory research use ... in neutral buffered formalin and embedded in ... performed by certified pathologists. Tissue cores ... relocated into a new recipient paraffin block, ...
... The kit contains all the reagents required ... NADPH-cytochrome c reductase activity in cell and ... reticulum (ER)]. It has been tested on ... liver, kidney, brain, spleen, and heart muscle ...
... pET Host Strain Competent Cell Sets ... vector/host strain combinations The most ... E. coli is to use ... be prepared in the laboratory, greater efficiency, ...
The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver une...
Biology Products: