Navigation Links
Media highlights in the January issues of Biophysical Journal
Date:1/29/2008

laxation
Christoph P Riethmuller, University of Munster Hans Oberleithner, University of Munster Marianne Wilhelmi, University of Munster Jonas Franz, University of Munster Eberhard Schlatter, University of Munster Jens Klokkers, University of Munster Bayram Edemir, University of Munster
Keywords: AFM; Aquaporin; Elasticity; Epithelial cells; Force Mapping; Kidney

The study adds a biomechanical perspective to the knowledge of vesicle transport regulation. Shuttling vesicle-embedded proteins from cytosol to the plasma membrane is an essential process for living cells. Biochemists have discovered a high number of proteins that contribute to this intricate regulation mostly by monitoring their phosphorylation status. Likewise numerous biophysical studies have explored the mechanics of single motor proteins of the myosin, dynein and kinesin families involved.

Here, a biomechanical approach is taken, where in living cells the tension of the cytoskeletal network is monitored by atomic force microscopy. This network spans all cells and thereby constitutes a supramolecular (mesoscopic) stiffness of the cell body.

The idea of the authors was that vesicles, driven by motor proteins along a fiber, face a resistance of crossing fibers, which varies with the tension of this network. The experiments performed on rat kidney cells favor this view. The vesicle transport is accelerated when the network fibers relax. In simple words, a physically relaxed cell is doing much better in vesicle transport compared to a cell under tension. This finding indicates that intracellular vesicle trafficking has a strong biomechanical component.


'/>"/>

Contact: Ellen R. Weiss
eweiss@biophysics.org
301-634-7176
Biophysical Society
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. February Geology and GSA Today media highlights
2. Media advisory -- 2008 Ocean Sciences Meeting
3. Oliguridylation-mediated histone mRNA decay
4. Immediate action needed to save corals from climate change
5. Media highlights in the Dec. 15 issue of Biophysical Journal
6. Better protection for biomedial devices could result from Rutgers-Camden research
7. December GEOLOGY and GSA TODAY media highlights
8. Nanotechnology and the media: The inside story
9. November GEOLOGY and GSA TODAY Media Highlights
10. Media highlights in the November issues of Biophysical Journal
11. October Geology and GSA Today media highlights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... A new report from the Wildlife Conservation Society ... only help economically valuable species such as lobster, ... also help re-colonize nearby reef areas. , The ... a systematic review of research literature from no-take ... by Dr. Craig Dahlgren, a recognized expert in ...
(Date:7/11/2014)... a new professorship in tissue engineering to promote ... Engineering and the Marine Biological Laboratory, supported by ... Eugene Bell Foundation., The Eugene Bell Professorship in ... Molecular Engineering. That endowed chair holder also will ... Bell Center for Regenerative Biology and Tissue Engineering, ...
(Date:7/11/2014)... from Salk Institute for Biological Studies, BGI, and ... safety and reliability of the existing targeted gene ... TALEN-HDAdV, which could significantly increased gene-correction efficiency in ... published online in Cell Stell Cell ... gene therapy. , The combination of stem cells ...
Breaking Biology News(10 mins):Belize's lobster, conch, and fish populations rebuild in no-take zones 2New professorship in tissue engineering links molecular engineering, marine biology 2A new genome editing method brings the possibility of gene therapies closer to reality 2
... Oct. 17, 2011 Dr. Randal Halfmann, a ... of 10 investigators selected for the first National Institutes ... new program allows creative early-career scientists to leapfrog the ... independent investigations. The charter group of awardees will share ...
... Oct. 17, 2011 Aware, Inc. (Nasdaq: ... software, today announced the development of the Next-Generation Universal ... agencies of the U.S. Department of Justice. Universal ABS ... BioComponents™ product family; a flexible, modular, COTS software framework ...
... Ga. Nearly all active people suffer ankle sprains at ... Georgia study suggests that the different ways people move their ... In the past, sports medicine therapists prescribed strengthening and ... The study by UGA kinesiology researchers, published in the early ...
Cached Biology News:UT Southwestern biochemist receives new NIH Early Independence Award 2Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 2Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 3Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 4UGA study suggests key to avoiding ankle re-injury may be in the hips and knees 2
(Date:7/10/2014)... July 10, 2014 Product and ... very low abundance and are often “lost in ... time-consuming. , Join presenters Dr. Rowel Tobias, Senior ... John Anders, Head of Quality at Nanotherapeutics, Inc., ... that can speed detection and quantitation while achieving ...
(Date:7/10/2014)... Robert Harman, DVM, Founder and CEO of Vet-Stem, ... announce the relaunch of his highly informative blog, now named ... “ What are Stem Cells ?” Dr. Harman’s purpose ... in the basics of stem cell therapy so that pet ... of treatment when considering regenerative medicine. , A veterinarian by ...
(Date:7/10/2014)... 10, 2014 On July 9 ... , presented Russia,s first national ... The Company is developing a unique project called ... develops a number of innovative drugs based on monoclonal ... ceremony took place at the International Exhibition "Innoprom 2014" ...
(Date:7/10/2014)... D.C., April 15, 2014 -- According to the ... to nuclear security comes from terrorists acquiring sufficient ... to construct a crude nuclear explosive device. The ... nuclear trafficking have involved gram-level quantities, which can ... , According to a new study appearing this ...
Breaking Biology Technology:Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2Sensitive detection method may help impede illicit nuclear trafficking 2
... , , , , , ... -- Biostar,Pharmaceuticals, Inc. (OTC Bulletin Board: BSPM) ("Biostar" or ... and medical nutrients addressing a variety of diseases and ... flagship Xin Aoxing,Oleanolic Acid ("Xin Aoxing") Capsules for the ...
... , , ORLANDO, Fla., Dec. ... GNLK) a leading consumer genomics and biotechnology company ( www.genelinkbio.com ... Macdonald as its interim Chief Executive Officer, effective December 28, ... leader with more than 25 years of experience building high ...
... , , , , , , , , ... ( SVA),a leading provider of biopharmaceutical products in China, announced today,that ... (SFDA) to commence a human clinical trial for its vaccine,against human ... This is the first clinical trial application for HFMD vaccine,submitted in ...
Cached Biology Technology:Biostar Pharmaceuticals, Inc. to Launch Xin Aoxing Oleanolic Acid Capsules in Beijing and Shanghai 2Biostar Pharmaceuticals, Inc. to Launch Xin Aoxing Oleanolic Acid Capsules in Beijing and Shanghai 3David L. Macdonald Appointed CEO of GeneLink BioSciences, Inc. 2David L. Macdonald Appointed CEO of GeneLink BioSciences, Inc. 3David L. Macdonald Appointed CEO of GeneLink BioSciences, Inc. 4Sinovac Files Clinical Trial Application with SFDA for Vaccine Against Hand, Foot, and Mouth Disease 2Sinovac Files Clinical Trial Application with SFDA for Vaccine Against Hand, Foot, and Mouth Disease 3Sinovac Files Clinical Trial Application with SFDA for Vaccine Against Hand, Foot, and Mouth Disease 4
Mouse monoclonal antibody raised against a full length recombinant YARS. NCBI Entrez Gene ID = YARS...
... Sight DS-L2 imaging controller is a successor ... and allows users to comfortably observe, record ... controller features an 8.4 inch LCD (XGA) ... of Nikon cameras including the DS-Fi1 , ...
... is a premium quality recombinant form of ... is suitable for a wide range of ... and reproducible performance, each preparation is extensively ... assays. NovaTaq DNA Polymerase possesses an integral ...
Mouse polyclonal antibody raised against a partial recombinant TSEN2. NCBI Entrez Gene ID = 80746...
Biology Products: