Navigation Links
Media highlights in the January issues of Biophysical Journal
Date:1/29/2008

laxation
Christoph P Riethmuller, University of Munster Hans Oberleithner, University of Munster Marianne Wilhelmi, University of Munster Jonas Franz, University of Munster Eberhard Schlatter, University of Munster Jens Klokkers, University of Munster Bayram Edemir, University of Munster
Keywords: AFM; Aquaporin; Elasticity; Epithelial cells; Force Mapping; Kidney

The study adds a biomechanical perspective to the knowledge of vesicle transport regulation. Shuttling vesicle-embedded proteins from cytosol to the plasma membrane is an essential process for living cells. Biochemists have discovered a high number of proteins that contribute to this intricate regulation mostly by monitoring their phosphorylation status. Likewise numerous biophysical studies have explored the mechanics of single motor proteins of the myosin, dynein and kinesin families involved.

Here, a biomechanical approach is taken, where in living cells the tension of the cytoskeletal network is monitored by atomic force microscopy. This network spans all cells and thereby constitutes a supramolecular (mesoscopic) stiffness of the cell body.

The idea of the authors was that vesicles, driven by motor proteins along a fiber, face a resistance of crossing fibers, which varies with the tension of this network. The experiments performed on rat kidney cells favor this view. The vesicle transport is accelerated when the network fibers relax. In simple words, a physically relaxed cell is doing much better in vesicle transport compared to a cell under tension. This finding indicates that intracellular vesicle trafficking has a strong biomechanical component.


'/>"/>

Contact: Ellen R. Weiss
eweiss@biophysics.org
301-634-7176
Biophysical Society
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. February Geology and GSA Today media highlights
2. Media advisory -- 2008 Ocean Sciences Meeting
3. Oliguridylation-mediated histone mRNA decay
4. Immediate action needed to save corals from climate change
5. Media highlights in the Dec. 15 issue of Biophysical Journal
6. Better protection for biomedial devices could result from Rutgers-Camden research
7. December GEOLOGY and GSA TODAY media highlights
8. Nanotechnology and the media: The inside story
9. November GEOLOGY and GSA TODAY Media Highlights
10. Media highlights in the November issues of Biophysical Journal
11. October Geology and GSA Today media highlights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... , July 27, 2015   Zynx Health ... experience-based clinical improvement solutions, today announced that its ... now available on Android smartphones and tablets. With ... post-care organizations can use ZynxCarebook to securely exchange ... condition, streamline care transitions to other care settings, ...
(Date:7/21/2015)... , July 21, 2015 Passwords have ... seen in the recent U.S. Office of Personnel ... to the infosec conundrum, but developers and end-users ... To address this dilemma, Biometrics-as-a-Service provider HYPR Corp. ... Tokenization SDK for third party integration. ...
(Date:7/9/2015)... 2015 Research and ... the "Biometrics for Banking; Market & Technology ... to their offering. The adoption for ... growth and the forecast is that by 2020 ... companies involved in delivering biometric systems to the ...
Breaking Biology News(10 mins):Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3
... evangelical movement is defined has profound implications for where ... study by sociologists at Rice University and the University ... much debate over whether Sen. Obama can shave off ... Rice,s D. Michael Lindsay, one of the researchers. "That ...
... , Plants that grow more slowly stay ... Biology, scientists at the Max Planck Institute for Developmental ... of genes, so-called microRNAs, coordinate growth and aging processes ... TCP transcription factors. These transcription factors in turn influence ...
... for Applied Physics will be awarded to Phaedon Avouris ... electrical and optical properties of nanoscale carbon materials including ... The award, accompanied by US$ 5,000, will be presented ... at Harvard University in Cambridge, MA, on 27 September ...
Cached Biology News:New study looks to define evangelicals and how they affect polling 2Formula discovered for longer plant life 2Carbon nanostructures form the future of electronics and optoelectronics 2
(Date:8/3/2015)... , August 3, 2015 ... Portland Hospital waved the shortfall of ... could stand normally for the first time. ... (Photo: http://photos.prnewswire.com/prnh/20150803/254229 ) The Selective ... legs allowing him to carry out his wish to ...
(Date:8/3/2015)... LOUIS (PRWEB) , ... August 03, 2015 , ... Nine ... in Iowa, Illinois and Indiana. Hosted by the Soil Health Partnership , the ... create lasting environmental benefits while potentially increasing farm productivity and income. , Brent Bible ...
(Date:8/3/2015)... 2015 According to a new ... Culture: Asia to Witness Highest ... global 3D cell culture market was valued at US$ 586.1 Mn ... CAGR of 29.1% to account for US$ 2,717.6 Mn ... http://www.persistencemarketresearch.com/market-research/3d-cell-cultures-market.asp 3D cell culture refers to ...
(Date:7/31/2015)... ... July 31, 2015 , ... Global Resorcinol ... premium industry insights on the global resorcinol industry. The report highlights the various ... vivid market scenarios and analysis of primary and secondary inputs from the existing ...
Breaking Biology Technology:Cerebral Palsy Operation by The Portland Hospital Allows a Boy to Stand Properly for the First Time 2Cerebral Palsy Operation by The Portland Hospital Allows a Boy to Stand Properly for the First Time 3Soil Health Field Days Kick Off Throughout Midwest 2Soil Health Field Days Kick Off Throughout Midwest 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4
... announced that data from Phase 2 studies for its ... (SB939) demonstrate promising activity in patients with myelofibrosis (MF). ... Meeting and Exposition in San Diego, Calif. ... activity in alleviating MF-associated splenomegaly and constitutional symptoms with ...
... field of vision is a step closer to reality with ... provide the wearer with hands-free information updates. In ... Journal of Micromechanics and Microengineering , researchers constructed a computerised ... live eyes. There were no signs of adverse side effects. ...
... Office of Scientific Research (AFOSR) was chosen by Time Magazine for ... Ali Aliev, Yuri Gartstein and Ray Baughman, of the University of ... referred to as the "mirage effect from thermally modulated transparent carbon ... it: an ,invisibility cloak,." The key ...
Cached Biology Technology:S*BIO's Novel JAK2 Inhibitor Pacritinib (SB1518) and Histone Deacetylase Inhibitor Pracinostat (SB939) Demonstrate Promising Activity in Phase 2 Studies for Patients with Myelofibrosis (MF) 2S*BIO's Novel JAK2 Inhibitor Pacritinib (SB1518) and Histone Deacetylase Inhibitor Pracinostat (SB939) Demonstrate Promising Activity in Phase 2 Studies for Patients with Myelofibrosis (MF) 3Terminator-style info-vision takes step towards reality 2
... length insert sequencing service for large insert ... Agencourt utilizes unique library construction techniques ... are several features that allow Agencourt to ... turnaround including our patented magnetic bead-based SPRI ...
... maintenance, calibration, and validation (MCV) ... plate used for hands-free startup, ... using the Bio-Plex suspension array ... for use with Bio-Plex Manager ...
A flexible 24-48 hour DNA sequencing service. Samples may be shipped in standard 1.5mL tubes. Oligo synthesis and DNA preparation available. Read lengths up to 850 Phred 20 bases. Universal primers p...
... Agencourts cDNA sequencing and finishing services ... Agencourt can perform large-scale 5' screening ... finishing. Our considerable experience with large-scale ... make Agencourt an ideal cDNA outsourcing ...
Biology Products: