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Media highlights for February in Biophysical Journal
Date:3/10/2008

under a constant pulling force, the speed of translocation is not uniform; and that a molecule twice as long does not take twice, but four times longer to translocate.

Having unraveled the memory effects of the molecule, we are in a pivotal position to devise new methods to suppress or enhance these memory effects --- and consequently, the back-and-forth fluctuation movements of the molecule through the pore --- by putting in control mechanisms to suit situation-specific requirements. For example, to facilitate faster delivery of drug molecules or healthy gene fragments one needs to suppress the memory effects, while to advance single-molecule characterization techniques using translocation, enhancement of the memory effects is required, so that a given part of the molecule revisits the pore more frequently.


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Contact: Ellen R. Weiss
eweiss@biophysics.org
301-634-7176
Biophysical Society
Source:Eurekalert

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