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Mechanisms involved in resistance to the bacteria Salmonella studied in a Ph.D. thesis
Date:2/6/2013

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These results have enabled researchers to get a better idea about the mechanism by which Salmonella activates the formation of biofilm. "We have generated new knowledge that could be used to design new strategies to help to prevent the formation of biofilm in our factories and on our farms," as Violeta Zorraquino pointed out.

Bacterial motility

The second part of her research focussed on studying the effect of the same molecule (c-di-GMP) in another of Salmonella's biological processes: bacterial motility.A bacterium is capable of moving freely in a liquid medium by rotating its flagella, and when it reaches a suitable surface, it sticks to it and begins to create the biofilm."There is an intervening stepbetween being motile and sticking to a surfacein which the bacterium has to stop the rotation of its flagella completely. We have discovered what is responsible for this intervening step: cellulose, which is a component of biofilm, and the synthesis of which is activated in the presence of the c-di-GMP molecule."


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Contact: Oihane Lakar Iraizoz
o.lakar@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

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