Navigation Links
Mechanisms involved in resistance to the bacteria Salmonella studied in a Ph.D. thesis
Date:2/6/2013

This press release is available in Spanish.

In their natural environment bacteria develop by forming communities of micro-organisms called biofilms that afford them greater resistance. These biofilms on farms and premises where food is processed lead to considerable economic losses besides being a potential source of contamination and transmission of the pathogen. In her PhD thesis,Violeta Zorraquino-Salvo has studied a specific protein type that activates the formation of biofilm in Salmonella and regulates bacterial motility. "Having a better idea of the mechanisms involved in these processes will help to design new, more effective strategies for preventing the formation of biofilm and its potential harm in the clinical, food and industrial ambit," points out the researcher.

Two decades ago it was discovered that a small molecule (the so-called c-di-GMP) could on its own hamper motility and activate the formation of biofilm. "This molecule is part of a signal transduction system: there are different sensory membranes on the membrane of the bacteria that pick up stimuli from the outside and transduce them into different intracellular levels of c-di-GMP, thus regulating different biological processes like biofilm formation. "In the first part of her thesis Zorraquino removed all the sensory proteins from the Salmonella's genome."We created a mutant Salmonella incapable of picking up stimuli from the medium in which it lives and therefore of producing biofilm under any circumstances. "After that, each sensory protein was inserted one by one to be able to analyse, under different ambient conditions, how each one contributed to the formation of biofilm. "We showed that under each condition tested, only some proteins are active, so each one is most likely responsible for the formation of biofilm whena given condition is present."<
'/>"/>

Contact: Oihane Lakar Iraizoz
o.lakar@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2

Related biology news :

1. FASEB SRC announces: Molecular Mechanisms & Physiological Consequences of Protein Aggregation
2. FASEB SRC announces conference registration open for: Neural Mechanisms in Cardiovascular Regulation
3. FASEB SRC announces conference registration open for: Mechanisms in Plant Development Conference
4. X-rays reveal the self-defence mechanisms of bacteria
5. Mechanisms for a beneficial effect of moderate alcohol consumption on osteoporosis in women
6. Researchers identify mechanisms that allow embryonic stem cells to become any cell in the human body
7. Force of nature: Defining the mechanical mechanisms in living cells
8. Symposium: Protein-Folding Diseases: Models & Mechanisms
9. Discovery of mechanisms predicting response to new treatments in colon cancer
10. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
11. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... March 31, 2015   Guidepoint , a leading ... the Post-Surgical Pain Management TRACKER, part of the ... trends in the medical device and therapeutics markets. The ... including treatment volumes, market share, and adoption rates across ... with joint surgery. The Post-Surgical Pain Management ...
(Date:3/24/2015)... 24, 2015   NexID Biometrics LLC, whose ... needs, today announced the beginning of shipments of version ... The company, based in Potsdam, N.Y. ... Connect:ID Expo, which began here today at the Walter ... 2.0 of its SDK boosts the accuracy rate range ...
(Date:3/23/2015)... --NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... market, announces its biometric payment technology, the Wocket® smart wallet, ... March 30 th . The new ... York markets. Gino Pereira ... new ad campaign following the recent initial shipment of Wocket ...
Breaking Biology News(10 mins):Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3
... Scientists at the Salk Institute for Biological Studies ... plants to adapt to various environments, but could also benefit ... March 6 in Nature , the findings show that ... world, their epigenomic makeup is as varied as the environments ...
... (CUMC) researchers have found the first evidence that selective ... hippocampus, can reduce anxiety without affecting learning. The findings ... be used to treat certain anxiety disorders, such as ... cognitive side effects. The study, conducted in mice, was ...
... MA "Use it or lose it." The saying ... to protecting against Alzheimer,s disease. Previous studies have shown ... may help delay the onset of dementia in Alzheimer,s ... Dennis Selkoe, MD, co-director of the Center for Neurologic ...
Cached Biology News:Hidden layer of genome unveils how plants may adapt to environments throughout the world 2Hidden layer of genome unveils how plants may adapt to environments throughout the world 3Portion of hippocampus found to play role in modulating anxiety 2Portion of hippocampus found to play role in modulating anxiety 3Use it or lose it 2
(Date:4/16/2015)... 2015 Avelas Biosciences, an in vivo ... announced today that it has initiated a Phase 1b ... women with primary, non-recurrent breast cancer undergoing surgery. In ... addition of Steven Chen , M.D., as vice ... dose escalation study will enroll up to 39 women ...
(Date:4/16/2015)... Switzerland , April 16, ... part of Debiopharm Group ™ , a Swiss-based ... target unmet medical needs as well as ... on the investigational compounds Debio 1143 (SMAC mimetic) ... presented at the 2015 Annual meeting of ...
(Date:4/16/2015)... Madison, NJ (PRWEB) April 16, 2015 ... recruited Dr. Joseph V. Gulfo to become the ... and Entrepreneurship. Simultaneously, FDU announced the kick-off of ... new program spearheaded by Dr. Gulfo, under the ... Silberman College of Business) and in collaboration with ...
(Date:4/16/2015)... Dana-Farber Cancer Institute and its Belfer ... Inc. today announced the successful completion of a ... ready, Next Generation Sequencing (NGS) assay for non-small ... first to demonstrate the successful sequencing of clinically ... plasma samples and highlights the ability to discover ...
Breaking Biology Technology:Avelas Biosciences Initiates Phase 1b Trial of AVB-620 in Breast Cancer Patients 2Avelas Biosciences Initiates Phase 1b Trial of AVB-620 in Breast Cancer Patients 3Debiopharm International SA Announces Results of 2 Key Oncology Programs at 2015 AACR Conference 2Debiopharm International SA Announces Results of 2 Key Oncology Programs at 2015 AACR Conference 3Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 2Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 3Resolution Bioscience announces successful collaboration on a novel, non-invasive, targeted NGS test for lung cancer 2Resolution Bioscience announces successful collaboration on a novel, non-invasive, targeted NGS test for lung cancer 3
... - Five years removed from the dotcom bubble, when ... value of the online world, new business models that ... progressive in their cutting-edge approach to business and traditional ... picture of those business models was made clearer by ...
... Seven months after Journal Communications announced ... its shareholders, the company has instead decided to sell ... , ,Q-Comm and Journal Communications have signed a definitive ... the stock of Norlight, subject to federal and state ...
... shape, the issue of Net Neutrality will likely surface at ... all indications, U.S. Reps. John Dingell , D-Michigan, and ... issue to the 2007 legislative agenda. , ,Even Rep. ... has weighed in that something needs to be done. The ...
Cached Biology Technology:Web-centric entrepreneurs find models that attract investment 2Web-centric entrepreneurs find models that attract investment 3Web-centric entrepreneurs find models that attract investment 4Web-centric entrepreneurs find models that attract investment 5Journal to sell Norlight Telecommunications 2Net neutrality: To control or not control, that is the question 2Net neutrality: To control or not control, that is the question 3