Navigation Links
Mechanisms for a beneficial effect of moderate alcohol consumption on osteoporosis in women
Date:8/2/2012

Women after menopause tend to develop weaker bones from what is known as osteoporosis, which may lead to fractures (especially hip fractures) from falling. The weakness of the bones results from an imbalance between the normal resorption (a type of dissolving of old bone) and the laying down of new bone, an ongoing process for both men and women referred to as "bone turnover." For poorly understood reasons, after menopause the resorption of old bone in women continues but new bone is laid down less well, leading to a decrease in bone density. A variety of substances (calcium, vitamin D and various medications) have been used in an attempt to prevent the development of osteoporosis; in epidemiologic studies, moderate drinking of alcohol has also been shown to lower this risk.

An intervention by Marrone JA et al published in Menopause, involved 40 healthy postmenopausal women of an average age of 56. The authors measured factors that relate to osteoporosis in post-menopausal women while subjects were consuming alcohol (19g a day), after they had stopped drinking, and after they had resumed their alcohol consumption. The authors state that excessive bone turnover, combined with an imbalance whereby bone resorption exceeds bone formation, is the principal cause of post-menopausal bone loss and conclude that alcohol decreases the turnover of bone in post-menopausal women, which leads to less resorption of bone, hence less osteoporosis. The study also showed that abstinence from alcohol resulted in increased markers of bone turnover (hence, higher risk of developing osteoporosis), whereas resumption of alcohol consumption reduced bone turnover markers.

The authors attribute a cellular mechanism for the observed lower risk of osteoporosis among women who consume moderate amounts of alcohol.

International Scientific Forum on Alcohol Research reviewers considered this to be an innovative and well-done study. The key ques
'/>"/>

Contact: R. Curtis Ellison
ellison@bu.edu
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
2. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
3. Discovery of mechanisms predicting response to new treatments in colon cancer
4. Symposium: Protein-Folding Diseases: Models & Mechanisms
5. Force of nature: Defining the mechanical mechanisms in living cells
6. Researchers identify mechanisms that allow embryonic stem cells to become any cell in the human body
7. Plant perfumes woo beneficial bugs
8. Beneficial bacteria may help ward off infection
9. Effects of environmental toxicants reach down through generations
10. More effective method of imaging proteins
11. The effect of catch-up growth by various diets and resveratrol intervention on bone status
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... 14, 2015  HYPR Corp. today announced it ... ) Alliance tm , an industry consortium transforming ... to share technology and collaborate to deliver open ... more secure and private, and easier to use. ... that protects sensitive user information and eliminates the ...
(Date:4/13/2015)... , April 13, 2015 ... TechSci Research, "Global Biometrics Market Forecast & Opportunities, 2020", ... a CAGR of around 14% till 2020. The ... for large scale implementation and review of biometric ... launch of new products with greater efficiency, are ...
(Date:4/10/2015)... , April 10, 2015 Research ... of the "Security Competitive Profiles - NEC" ... , NEC will continue to supply a ... the market, with a company focus on the development ... Winning opportunities in the Asia-Pacific ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2
... learning more about how protein gets in the urine when ... blocks it. "We have known for a long time ... in diabetes," said Dr. David Pollock, renal physiologist at the ... that a new class of drugs called endothelin A receptor ...
... days of critical international discussion and debate, led by ... Clinical Densitometry (ISCD) and the International Osteoporosis Foundation (IOF), ... pertaining to the interpretation and use of FRAX in ... Tool (FRAX), with models for some 26 countries, is ...
... that applying a stem cell-infused patch together with overexpression ... to damaged cardiac tissue following heart attack and resulted ... also found that function improved more so than when ... that is being studied elsewhere. These findings are ...
Cached Biology News:Scientists learn more about how kidneys fail and how new drugs may intervene 2International discussions on FRAX smooth the way for implementation in clinical practice 2Stem cell patch may result in improved function following heart attack 2Stem cell patch may result in improved function following heart attack 3
(Date:4/27/2015)... 27, 2015 SynGen Inc., a company that ... that harvest stem and progenitor cells from umbilical cord ... today that it has added three new members to ... Blood Business Units focus on product commercialization. ... its Vice President and Chief Financial Officer.  Chuck was ...
(Date:4/27/2015)... tru Shrimp™ Systems announced today that ... University for the exclusive worldwide rights to commercialize Tidal ... The license agreement for the patented technology, developed by ... such as China, Taiwan, France, Germany, Italy, Spain, the ... had inquires from all over the world for our ...
(Date:4/24/2015)... Top student social innovators from the ... universities, including UCSD and SDSU, will pitch their impact ... national and nonprofit companies for an opportunity to win ... Social Innovation Challenge 2015 . , The 2015 Social ... addressing a diverse range of issues including poverty, education, ...
(Date:4/24/2015)... 24, 2015  Pfenex Inc. (NYSE MKT: PFNX) a ... therapeutics including high value and difficult to manufacture proteins, ... of 6,000,000 shares of its common stock at a ... the shares being offered, 2,610,000 are being offered by ... by existing stockholders. Pfenex will not receive any proceeds ...
Breaking Biology Technology:SynGen Inc. Expands Its Management Team 2tru Shrimp™ Systems Acquires Global Patent for Tidal Basin™ Shrimp Production 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 3Pfenex Inc. Announces Pricing Of Follow-on Offering 2
... BioLife Solutions, Inc. (OTCBB: BLFS), a leading developer ... for cells and tissues, today announced that it ... cryopreservation media for umbilical cord blood stem cells, ... market. BioLife Solutions, which will be exhibiting at ...
... University say they have discovered a simple method for ... nanostructure that some believe could replace silicon as the ... intense scientific research in recent years, graphene is a ... atoms arranged in a hexagonal lattice. It is the ...
... Drs. Samuel and Elenore Bogoch of BioRadar UK Ltd. announced ... of the EHEC lethal strains of E. Coli preceded the ... have been studied in laboratories in Germany and elsewhere since ... databases. Replikins are subsequences of the genome of an infectious ...
Cached Biology Technology:BioLife Solutions Now The Leading Supplier of Pre-Formulated GMP Cryopreservation Media for Umbilical Cord Blood Stem Cells 2BioLife Solutions Now The Leading Supplier of Pre-Formulated GMP Cryopreservation Media for Umbilical Cord Blood Stem Cells 3Northern Illinois University scientists find simple way to produce graphene 2Rising Replikin Counts in E. Coli in Germany Since 2005 Preceded Current E. Coli Outbreak 2Rising Replikin Counts in E. Coli in Germany Since 2005 Preceded Current E. Coli Outbreak 3
Tan solid. A glycoside used to permeabilize cellular membranes. Exhibits hemolytic activity. Contaminants: ash: ≤10%. Soluble in H 2 O. pH 4.4 - 4.6. RTECS VQ1400000, CAS 8047-15-2. References:...
Anti Autotaxin /ENPP2 , - (Rabbit)...
... yellow solid. An N-nitroso-containing diabetogenic compound ... donor in pancreatic islets. An antibiotic ... alkylation and DNA strand breaks in ... HPLC. Soluble in H 2 O. ...
Mouse monoclonal antibody to CDC2L5 - cell division cycle 2-like 5 (cholinesterase-related cell division controller)...
Biology Products: