Navigation Links
Mechanism explains link between apolipoprotein E and Alzheimer's disease
Date:6/11/2008

hin the brain and highlight the importance of lipidation to the function of ApoE. This work also explains the previous observation that inactivation of a gene which helps the brain to process lipids (called Abca1) resulted in decreased levels of ApoE along with a seemingly paradoxical elevation of A? levels and plaque formation in mice. "Our data suggest that therapeutic agents that increase the levels of lipidated forms of ApoE, including LXR agonists, represent a potentially efficacious therapy for AD," concludes Dr. Landreth.


'/>"/>

Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Source:Eurekalert

Page: 1 2

Related biology news :

1. Jefferson receives $11.6M NIH grant to study novel mechanisms of heart failure
2. Fruit fly avoidance mechanism could lead to new ways to control pain in humans
3. Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain
4. Scientists clarify a mechanism of epigenetic inheritance
5. CSHL scientists identify a mechanism that helps fruit flies lock-in memories
6. A common genetic mechanism discovered in nitrogen-fixing plants
7. Mechanisms of plant-fungi symbiosis characterized by DOE Joint Genome Institute
8. Scientists uncover a novel mechanism that regulates carbon dioxide fixation in plants
9. The Uukuniemi virus helps to explain the infection mechanism of bunyaviruses
10. USC researchers identify mechanism that controls activation of stem cells during hair regeneration
11. New treatment mechanisms for schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... , March 24, 2015   NexID Biometrics ... with critical security-authentication needs, today announced the beginning of ... (FFD) solution. The company, based in ... at the three-day Connect:ID Expo, which began here today ... NexID said version 2.0 of its SDK boosts the ...
(Date:3/23/2015)... -- SoundView Technology Group issues a new research update following ... smart wallet. SoundView was one of the selected user groups to ... Wocket in multiple scenarios and outlets. Soundview ... making both debit and credit card payments.  ... company meets their plans in 2015, it would push our ...
(Date:3/23/2015)... 23, 2015  In the 2014 fiscal year, irs.gov ... losses. This figure accounts for a fraction of the ... Nilson Report, exceeds $11 billion globally. The polygraph has ... crime has occurred. Investor Mark Saint Juste ... Joe Paolella partnered to administer the test in ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3
... red foxes originated from two separate genetic lineages that were ... years ago, according to a U.S. Forest Service Pacific Northwest ... issue of Science Findings, a monthly publication of ... populations of the species. "When most people think ...
... Rima Taher, an expert in the design ... will speak next week at the Annual Conference ... in Montreal. Taher, a university lecturer ... a civil and structural engineer, http://www.njit.edu/news/experts/taher.php . ...
... available in German . With the ... Forschungsgemeinschaft (DFG, German Research Foundation) is to establish 18 new ... Grants Committee in Bonn. The new institutions will initially be ... which time they will receive total funding of around 60 ...
Cached Biology News:Genetic study clarifies evolutionary origin of elusive montane red fox 2Better buildings for extreme climates will be focus of researcher's talk 2DFG establishes 18 new research training groups 2DFG establishes 18 new research training groups 3DFG establishes 18 new research training groups 4DFG establishes 18 new research training groups 5DFG establishes 18 new research training groups 6DFG establishes 18 new research training groups 7DFG establishes 18 new research training groups 8DFG establishes 18 new research training groups 9DFG establishes 18 new research training groups 10
(Date:4/1/2015)... 2015 Immunocore Limited ("the ... drugs to treat cancer, viral infections and autoimmune ... of Christina Coughlin as Chief Medical ... medical and regulatory leadership to the pre-clinical and ... Coughlin has extensive experience in oncology drug development, ...
(Date:3/31/2015)... , March 31, 2015  Biotest Pharmaceuticals Corporation ... pleased to announce the addition of its newest plasma ... 205 Conway, Arkansas . The over ... for business on March 26 th 2015 and ... to eighteen. "This facility represents another ...
(Date:3/31/2015)... 31, 2015 Eastern Kentucky University ... online bachelor’s of criminal justice degree programs by ... to inspiring ideas and high quality educational opportunities,” ... the University. We are confident that students will ... This is the site’s first “Students before Profits” ...
(Date:3/31/2015)... PA (PRWEB) March 31, 2015 Pittcon ... and Applied Spectroscopy, ended on March 12, in New ... at $21 million as estimated by the New Orleans ... more than 14,200 conferees and exhibitor personnel. Those ... of the conferee number. For the third year, the ...
Breaking Biology Technology:Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 2Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 3Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 4Biotest Pharmaceuticals Corporation Announces the Opening of its Newest Plasma Collection Facility in Conway, Arkansas 2EKU Ranked in Top 50 Among Online Criminal Justice Degrees 2Pittcon 2015 Hits the Big Easy in a Big Way 2Pittcon 2015 Hits the Big Easy in a Big Way 3Pittcon 2015 Hits the Big Easy in a Big Way 4
... Codexis, Inc., today,announced the appointment of Lynn Marcus-Wyner, ... responsible for managing the company,s,intellectual property strategy, activities, ... Vice President, General Counsel and Secretary., Dr. ... Senior,Director, Intellectual Assets US, she managed the United ...
... ENDO ), an innovative medical device company ... tissue and tumor,ablation, announced today that the American ... on its website the organization,s official,"best practice" document ... focal cryoablation, also called cryosurgery. The AUA,posting of ...
... Spectral Diagnostics Inc.,(TSX: SDI) today announced that it ... of Japan to obtain the exclusive development and ... for the treatment of,sepsis that removes endotoxin from ... Company will seek FDA approval for a combined ...
Cached Biology Technology:Codexis Names Vice President, Intellectual Property 2Best Practices Document on Cryoablation Posted on Website of American Urological Association 2Spectral to bring anti-sepsis therapy to the U.S. market 2Spectral to bring anti-sepsis therapy to the U.S. market 3
Request Info...
... and IHC Protocol Development ,Antibody Titer ... in Animal or Human Cells and ... and Tissues ,Peroxidase, Alkaline Phosphatase, Immunogold, ... Electron Microscopy ,Protein Localization in Transgenic ...
Request Info...
Ultra-sensitive, non-radioactive detection of Protein G. Measure Protein G levels quickly and easily....
Biology Products: