Navigation Links
Mechanism elucidated: How smell perception influences food intake
Date:2/10/2014

In animals, as in humans, hunger mechanisms are known to stimulate food intake. Hunger triggers a set of mechanisms that encourage feeding, for example by increasing sensory perceptions such as the sense of smell. The researchers have now succeeded in revealing what links hunger and increased smell perception in the brain, and the resulting urge to eat.

The researchers have discovered how this mechanism is initiated in the endocannabinoid system in mice. This system interconnects receptors located in the brain and involved in different sensations such as euphoria, anxiety, or even pain, that are also sensitive to cannabinoid substances, such as cannabis.

The researchers discovered that the CB1 cannabinoid receptors control a circuit that connects the olfactory bulb (the region in the nervous system that initially handles olfactory information, located above the nose) to the olfactory cortex (higher structures of the brain). When the sensation of hunger is felt, it triggers the activity of the cannabinoid receptors, which in turn activate the olfactory circuit, which then becomes more responsive.

It is therefore this biological mechanism that brings about the increased sensitivity to smell during hunger, explaining one of the reasons for food intake and attraction to food.

The researchers expect that the circuit involved in the olfactory system is altered in obese or anorexic patients, and that sensitivity to smell may be more or less strong compared to normal. Elucidation of the biological mechanism will allow better management of these types of pathologies.


'/>"/>

Contact: Giovanni Marsicano
giovanni.marsicano@inserm.fr
33-557-573-756
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert  

Page: 1

Related biology news :

1. Mechanism for Burgess Shale-type preservation
2. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
3. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
4. Researchers unravel genetic mechanism of fatty liver disease in obese children
5. Mechanism found connecting metastatic breast cancer and arthritis
6. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
7. New genetic mechanism of immune deficiency discovered
8. Housekeeping mechanism for brain stem cells discovered
9. Carnegie Mellon fluorescent biosensor reveals mechanism critical to immune system amplification
10. Researchers find mechanism that gives plants balance
11. New key mechanism in cell division discovered
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mechanism elucidated: How smell perception influences food intake
(Date:3/18/2016)... LONDON , March 18, 2016 ... Established Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical ... & security companies in the border security market and ... and Europe has led ... your companies improved success. --> defence & ...
(Date:3/14/2016)... 2016 http://www.apimages.com ) - ... - Renvoi : image disponible via AP Images ... --> DERMALOG, le leader de ... lecteurs d,empreintes digitales pour l,enregistrement des réfugiés en ... pour produire des cartes d,identité aux réfugiés. DERMALOG ...
(Date:3/9/2016)... March 9, 2016 This BCC Research report ... of the RNA Sequencing (RNA Seq) market for the ... instruments, tools and reagents, data analysis, and services. ... of the RNA-Sequencing market such as RNA-Sequencing tools and ... main factors affecting each segment and forecast their market ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... 25, 2016 , ... Scientists at the University of Athens say they have ... be hampering the research that could lead to one good one. Surviving Mesothelioma has ... now. , The team evaluated 98 mesothelioma patients who got a ...
(Date:5/24/2016)... 2016   MedyMatch Technology Ltd ., the data analytics ... decision support tools in the emergency room, announced today that ... Advanced Technology Industries (IATI) BioMed Conference. The ... 15th National Life Sciences and Technology Week, and is being ... in Tel Aviv, Israel . Gene ...
(Date:5/23/2016)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), a ... of Directors has approved the payment of a quarterly cash ... The cash dividend of $0.24 per share will ... of record as of the close of business on June ... of the Board of Directors and may be adjusted as ...
(Date:5/22/2016)... ... ... Doctors in Rome say micronutrients found in certain foods have the potential to ... posted an article on the new research. Click here to read it now. ... Medicine evaluated more than 150 studies on polyphenols in cancer for their report recently ...
Breaking Biology Technology: