Navigation Links
Measuring segments of genetic material may help predict and monitor recurrence after thyroid cancer
Date:10/27/2013

A new analysis has found that the presence of short segments of genetic material (known as microRNA) within papillary thyroid cancer tumors suggests a likelihood of recurrence after patients undergo surgery. The study, which is published early online in CANCER, a peer-reviewed journal of the American Cancer Society, also found that elevated blood levels of the genetic material after surgery may indicate a higher possibility of recurrence after thyroidectomy.

MicroRNAs are copies of very short segments of genetic material that modulate gene expression. Researchers have found that dysregulation of microRNAs may play a role in the development of cancer, and microRNA profiles or "signatures" may be used to classify different types of thyroid tumors.

By studying tumor tissue from patients with papillary thyroid cancer, the most common endocrine malignancy, PhD candidate James Lee*, MBBS, FRACS, of the Kolling Institute of Medical Research and University of Sydney in Australia, under supervision from Professor Stan Sidhu, and his colleagues found that high levels of two specific microRNAs (microRNA-222 and -146b) within tumors indicated that cancer was more likely to recur after patients' tumors were surgically removed.

"This kind of test may help doctors select which patients may need more aggressive additional treatment after surgery, or be monitored more closely after initial treatment," said Lee. "As most patients with papillary type thyroid cancer do very well with standard treatment, we are always working on ways to help us select the small group that do not fair so well so we can use our medical resources more efficiently and minimize interruptions to patients' lives."

Also, the same two microRNAs were present at high levels in the blood of thyroid cancer patients compared with healthy individuals, but after thyroid surgery, the blood levels in the patients fell to normal levels. "This suggests that we may be able
'/>"/>

Contact: Amy Molnar
sciencenewsroom@wiley.com
Wiley
Source:Eurekalert

Page: 1 2

Related biology news :

1. Oceanographers develop method for measuring the pace of life in deep sediments
2. Measuring our carbon footprint
3. Measuring progesterone receptor expression to improve hormone-receptor-positive cancer management
4. Measuring mercury levels: Nano-velcro detects water-borne toxic metals
5. Bringing measuring accuracy to radical treatment
6. Measuring dispersal -- how well are soft-sediment invertebrate communities connected on the seafloor?
7. Measuring the exertion of mini-basketball players
8. New protocol recommendations for measuring soil organic carbon sequestration
9. New tool for measuring frozen gas in ocean floor sediments
10. A new method for measuring the flow of traffic a street has to bear by measuring atmospheric noise
11. Measuring mercury: Common test may overestimate exposure from dental amalgam fillings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... , April 20, 2015 Huntington Memorial ... Valley to implant a new miniaturized, wireless monitoring sensor ... is the first and only FDA-approved heart failure monitoring ... admissions when used by physicians to manage heart failure. ... that is implanted in the pulmonary artery (PA) during ...
(Date:4/14/2015)... , April 14, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, ... for the 2015 New York Design Awards under the ... New York City Design Awards are part of a ... over 2,500 ratings from the marketplace, industry and judging ...
(Date:4/9/2015)... 2015 Synaptics Inc. (NASDAQ: SYNA ), a ... it will report financial results for the third quarter ... the close of market. The company will host a ... p.m. PT (5:00 p.m. ET), during which management may ... the live call, analysts and investors should dial 888-438-5524 ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3Synaptics to Report Third Quarter Results on April 23 2
... are highly valued by consumers yet their properties have ... a drain on our limited natural resources. Until now ... Laboratory (NPL) are working towards producing the world,s first ... results could help make synthetic products so good that ...
... ecologist Marijke van Kuijk has studied the regeneration of ... regenerate to tropical forest, but only slowly. Two procedures ... to free up space for trees and planting the ... to calculate the appropriate measures. People in ...
... shape and size of microscopic three-dimensional structures built out ... Shear and his former graduate student Bryan Kaehr at ... Kaehr fabricated a variety of detailed three-dimensional microstructures, known ... and bend the hydrogels by altering the chemistry of ...
Cached Biology News:Scientists set out to measure how we perceive naturalness 2Scientists set out to measure how we perceive naturalness 3Giving nature a helping hand 2'Smart' materials get smarter with ability to better control shape and size 2'Smart' materials get smarter with ability to better control shape and size 3
(Date:5/28/2015)... (PRWEB) May 28, 2015 Global ... a point to ask his audiences if they ... trends including robotics, solar cells, fuel cells, rapid ... printers, advanced battery storage technology, driverless cars, artificial ... high-quality but inexpensive online education. , While ...
(Date:5/28/2015)... May 28, 2015 Dr. Carl ... today that Roger L. Williams, MD, has joined ... Partners Premier Experts are top tier consultants whose ... extraordinary value to the company’s clients. Premier Experts ... help clients successfully develop their medical products, pursue ...
(Date:5/28/2015)... 28, 2015 Clinerion, an ... Switzerland, and the Alliance for Clinical Research ... non-profit organization operating in the public interest ... to enhance quality, safety, integrity and operational ... research, are pleased to announce their partnership ...
(Date:5/27/2015)... RXi Pharmaceuticals Corporation (NASDAQ: RXII ... developing innovative therapies primarily in the areas of ... a public offering of shares of its common ... stock and overallotment purchase rights to purchase shares ... stock, warrants and overallotment purchase rights are immediately ...
Breaking Biology Technology:Futurist Jack Uldrich to Deliver 4 Keynote Addresses in June 2Former CEO and Chair of the Council of Experts at the USP, Roger L. Williams, MD, Joins NDA Partners as a Premier Expert Consultant 2Clinerion and ACRES Partner on Patient Recruitment and Risk-Based Quality Management 2Clinerion and ACRES Partner on Patient Recruitment and Risk-Based Quality Management 3RXi Pharmaceuticals Announces Proposed Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces Proposed Public Offering of Common Stock and Warrants 3
... survival tend to favor the strongest, but University of ... of self-healing materials, it is the somewhat frail that ... Langmuir a new model laying out the inner ... that can regenerate after taking damage and are being ...
... 2011 Novavax, Inc. (Nasdaq: NVAX ) ... Singhvi, President and Chief Executive Officer of Novavax, will ... of Vaccine on March 23rd, 2011 at the China ... be giving a presentation on Commercialization Strategies for Vaccines ...
... "templated growth" technique for fabricating nanoribbons of epitaxial graphene ... that conduct current with almost no resistance. These ... made with conventional architectures and set the stage ... of the quantum properties of electrons. "We can ...
Cached Biology Technology:Only the weak survive?: Pitt team adds more give for stronger self-healing materials 2Templated growth technique produces graphene nanoribbons with metallic properties 2Templated growth technique produces graphene nanoribbons with metallic properties 3Templated growth technique produces graphene nanoribbons with metallic properties 4
...
BD FastImmune EDTA Solution. Applications: Flow Cytometry Storage Temperature: Refrigerate(2 to 8C)...
Autoclavable, variable volumefitted w./ an anti-drip safety valve; borosilicate glass barrelprotected with transparentpolypropylene sleeve; spring-lock cursor design ensuresfine adjustment for exact ...
...
Biology Products: