Navigation Links
Massive endocytosis in cells
Date:1/17/2011

In three papers in the January and February issues of the Journal of General Physiology (JGP), Don Hilgemann and colleagues have extensively characterized a previously unidentified process by which up to 75% of the cell plasma membrane can be reversibly endocytosed. This massive endocytosis ("MEND") can be elicited in a variety of cell types with a range of different experimental manipulations, including internal calcium transients in the presence of ATP, membrane treatment with sphingomyelinase, and introduction of various amphiphiles into the membrane bilayer. MEND does not employ the canonical endocytic mechanisms involving clathrin, the actin cytoskeleton or dynamins. MEND preferentially causes endocytosis of the low-ordered, cholesterol-containing membrane fraction. The mechanisms underlying MEND likely include the merger of nanoscopic low-ordered domains into larger domains with attendant changes in lipid line tension. Application of MEND promises to serve as a valuable tool in determining which membrane proteins are associated with low- or high-ordered membrane fractions.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. Massive gene loss linked to pathogens stealthy plant-dependent lifestyle
2. Volcano fuels massive phytoplankton bloom
3. Massive coral mortality following bleaching in Indonesia
4. GM crop produces massive gains for womens employment in India
5. DOE, ORNL officially join NSF on massive ecological study
6. Protein extremes gain relevance in massive proteomic studies
7. Massive resources now directed at sustainable animal waste technology
8. Massive Southern Ocean current discovered
9. Cool new tools let public contribute to massive interactive online biodiversity encyclopedia
10. Study highlights massive imbalances in global fertilizer use
11. New online report on massive jellyfish swarms released
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... (UM SOD) and Medicine (UM SOM) jointly announced ... million grant award from the National Institute of ... Institutes of Health to study the causes, prevention ... which renews a previous $12 million five-year NIAID-funded ... research by studying chlamydial and gonorrheal diseases as ...
(Date:7/29/2014)... to go and almost 2500 registered participants, the final ... The event, a joint venture between the Federation of ... for Biochemistry and Molecular Biology (SFBBM), will take place ... the Palais des Congrs in Paris, France. , The ... life sciences in Europe this year. It features more ...
(Date:7/29/2014)... it affects 1 in 100,000 people characterized by ... its cause remains unknown, a new study by a team ... Bonn in Germany and other European institutions confirms for the ... published on 6 July in Nature Genetics , is ... we swallow, a sphincter in the lower esophagus opens, allowing ...
Breaking Biology News(10 mins):University of Maryland Schools of Dentistry and Medicine receive NIH grant 2University of Maryland Schools of Dentistry and Medicine receive NIH grant 3University of Maryland Schools of Dentistry and Medicine receive NIH grant 4Counting down to FEBS-EMBO 2014 in Paris, France 2Mysterious esophagus disease is autoimmune after all 2
... Entomological Society of America (ESA) invites scientists to submit ... which will be held in Knoxville, Tennessee, November 11-14, ... This year,s theme is "A Global Society for ... reflect this theme, if possible. The deadline for ...
... Oilsands development uses a vast amount of water and ... the toxins and metals leftover from extracting and upgrading ... a lightening rod for controversy and a significant risk ... at the University of Calgary and engineers at the ...
... Hay fever (runny nose, sneezing, itchy eyes) is caused by ... These tiny grains bring misery to sufferers through spring and ... weather reports to help sufferers prepare. However new research published ... Allergy shows that, regardless of medication and other allergies, ...
Cached Biology News:Researchers develop new method of cleaning toxins from the oilsands 2Get ready for spring - hay fever worse in spring than summer 2
(Date:7/29/2014)... CLARA, Calif. , July 29, 2014 /PRNewswire-iReach/ ... services agreement with FORMA Therapeutics, Inc., to provide ... and proprietary fragment-based lead discovery platform for novel ... really excited about the opportunity to work with ... fields of epigenetics and protein homeostasis. FORMA Therapeutics, ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 July ... vaccine pioneer in the biotechnology industry, announced that ... Coast Securities, Inc. to explore financing opportunities that ... technology, a breakthrough vaccine platform with the potential ... The company exclusively licensed the well-established LAMP platform ...
(Date:7/29/2014)... Quorum Review IRB, the industry ... accreditation by the International Association of Six ... Sigma Deployment Program. The citation recognizes robust organizational ... Quorum’s Lean Six Sigma program was evaluated by ... The designation is a public statement of excellence ...
(Date:7/29/2014)... Boston, MA (PRWEB) July 29, 2014 ... the Library of Congress was recently awarded to Juliana ... in Stoneham, MA, for their project, “From an Egg, ... from among 3,000 final entries for the National History ... more than 300 historians and educators in Washington, D.C. ...
Breaking Biology Technology:Nanosyn Announces Expanded Partnership With FORMA Therapeutics 2Immunomic Therapeutics Engages Newport Coast Securities, Inc. 2Immunomic Therapeutics Engages Newport Coast Securities, Inc. 3Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 2Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 3In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 2In Vitro Fertilization (IVF) was the Subject of This Year’s Winning Entry for the Prestigious Library of Congress “Discovery or Exploration in History Award” 3
... Incorporated (Nasdaq: ARAY ), a global leader in ... results for its second quarter of fiscal 2011, ended December ... closes. A conference call to review the results ... be hosted by Euan S. Thomson, Ph.D., president and chief ...
... Registration is now open for StemCONN 2011. ... in stem cell research, will take place Tuesday, March ... session) and the UConn Health Center (commercial session and ... at http://stemconn.org/ . StemCONN 2011 will ...
... Md., Jan. 13, 2011 Celsion Corporation (Nasdaq: ... to the development and commercialization of innovative oncology drugs, ... securities purchase agreement with a select group of institutional ... to sell 5,000 shares of 8% redeemable convertible preferred ...
Cached Biology Technology:Accuray Incorporated to Report Financial Results for Second Quarter of Fiscal 2011 2Celsion Corporation Announces Convertible Preferred Stock Financing and Amended License Agreement for Aggregate Gross Proceeds of up to $9 Million 2Celsion Corporation Announces Convertible Preferred Stock Financing and Amended License Agreement for Aggregate Gross Proceeds of up to $9 Million 3Celsion Corporation Announces Convertible Preferred Stock Financing and Amended License Agreement for Aggregate Gross Proceeds of up to $9 Million 4
Purified Mouse anti-Hu LAT (pY226) Storage Temperature: Refrigerate(2 to 8C)...
Tris-EDTA Buffer Solution, 1X, pH 8.0, sterile, Molecular Biology Grade...
... the most comprehensive, cost-effective solution to ... incorporated unprecedented quality into both our ... proven detection chemistries and antibodies that ... protocol. It also includes our competitively ...
...
Biology Products: