Navigation Links
March of Dimes funds new preterm birth research
Date:3/4/2013

WHITE PLAINS, N.Y., March 5, 2013 Five researchers from four states are investigating how genetics and infections interact to cause preterm birth as well as how proteins and hormones regulate a healthy pregnancy, all with the goal of giving more babies a healthy start in life, the March of Dimes announced today.

The researchers will study the role that fetal fibronectin, a protein, plays in triggering premature rupture of the membranes; and how progesterone, a hormone that has been shown to prevent preterm birth in some women, helps a healthy pregnancy.

Nearly half a million babies one out of every nine are born too soon each year in the United States. Preterm birth is a serious health problem that costs the nation $26 billion annually. It is the leading cause of neonatal death, and babies who survive an early birth have increased risks of lung disease, cerebral palsy and intellectual and developmental disabilities, problems that can affect their health throughout their lives.

In 2011, the US preterm birth rate dropped to 11.7, the lowest in a decade, but still above the March of Dimes goal of lowering the national rate to 9.6 percent. That goal can be achieved in part by applying known strategies to prevent preterm birth, such as smoking cessation programs, progesterone treatments, and reducing early elective deliveries, the March of Dimes says. But the organization also believes continued research is needed to yield new medical advances to meet the goal.

The grants are awarded for three years and brings the March of Dimes nine-year-old Prematurity Research Initiative (PRI) Grant program's total grant to nearly $24 million. The PRI program is one of several March of Dimes grant programs available to researchers.

Jeffrey C. Murray, MD, at the University of Iowa Carver College of Medicine, identified possible genes involved in preterm birth with the support of a prior March of Dimes PRI grant. This year, funding for his work has been renewed to allow him to build on his past discoveries with the goal of improving health care providers' ability to predict which women are at high risk of delivering their baby too soon.

Other new grant recipients are:

  • Louis Ragolia, PhD, director of Biomedical Research, Winthrop University Hospital, Mineola New York, who is focusing on prostaglandins, specialized lipids that mediate inflammation and play an important role in triggering labor at term, to identify women at risk of infection-related preterm delivery and develop drug treatment to prevent it.

  • Indira U. Mysorekar, PhD, Washington University School of Medicine; St. Louis, Missouri, who is working to identify how bacteria and other infection-causing microorganisms attack the placenta and contribute to preterm birth.

  • Francesco J. DeMayo, PhD, Baylor College of Medicine, Texas, who is seeking to understand the role progesterone plays in suppressing contractions until term. The hormone has been shown to prevent premature delivery among about one-third of women with a singleton pregnancy.

  • Ruth Ann Word, MD, University of Texas Southwestern Medical Center, Dallas, is investigating the role of the protein fetal fibronectin in causing preterm premature rupture of the membranes (PPROM), which is associated with 30 to 40 percent of preterm deliveries in the U.S

In 2013, the March of Dimes celebrates its 75th Anniversary and its ongoing work to help babies get a healthy start in life. Early research led to the Salk and Sabin polio vaccines that all babies still receive. Other breakthroughs include new treatments for premature infants and children with birth defects. About 4 million babies are born each year in the United States, and all have benefitted the March of Dimes life saving research and education.


'/>"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Foundation
Source:Eurekalert

Related biology news :

1. March story tips
2. March of the pathogens: Parasite metabolism can foretell disease ranges under climate change
3. Southern insect scientists to meet in Baton Rouge in March
4. As climate warms, bark beetles march on high-elevation forests
5. March of Dimes awards $250,000 prize to 2 scientists who pioneered advances in skin disorders
6. UTMB scientist awarded $150,000 by March of Dimes
7. AGU journal highlights for March 29, 2012
8. Story tips From the Department of Energys Oak Ridge National Laboratory, March 2012
9. NIH funds research to identify Parkinsons biomarkers
10. NIH grant funds Boston College research into illnesses afflicting people living with HIV
11. Energy Deptartment funds UW project to turn wasted natural gas into diesel
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at ... between startups and global businesses, taking place in ... startups will showcase the solutions they have built with IBM ... France is one of the most ... increase in the number of startups created between 2012 and ...
(Date:5/6/2017)... 2017 RAM Group , Singaporean ... breakthrough in biometric authentication based on a ... to perform biometric authentication. These new sensors are based ... by Ram Group and its partners. This sensor will ... chains and security. Ram Group is a next ...
(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. (NASDAQ: ... announces the filing of its 2016 Annual Report on Form 10-K ... Commission. ... 10-K is available in the Investor Relations section of the Company,s ... the SEC,s website at http://www.sec.gov . 2016 Year ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... 2017 , ... A new study published in Fertility and ... in vitro fertilization (IVF) transfer cycles. The multi-center matched cohort study ... comparing the results from the fresh and frozen transfer cohorts, the authors of ...
(Date:10/10/2017)... ... , ... San Diego-based team building and cooking events company, Lajollacooks4u, has unveiled ... bold new look is part of a transformation to increase awareness, appeal to new ... , It will also expand its service offering from its signature gourmet cooking classes ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of ... award for Excellence in Volunteer Experience from US2020. , US2020’s mission is to ...
(Date:10/10/2017)... International research firm Parks Associates announced today that Tom ... 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and ...
Breaking Biology Technology: