Navigation Links
March of Dimes awards $250,000 prize to 2 scientists who pioneered advances in skin disorders
Date:4/29/2012

WHITE PLAINS, NY April 30, 2012 Two scientists who have revolutionized the understanding of skin biology, creating crucial advances in treating skin cancers and other diseases as well as severe burns, have been chosen to receive the 2012 March of Dimes Prize in Developmental Biology.

Howard Green, MD, George Higginson Professor of Cell Biology, Department of Cell Biology, Harvard Medical School, and Elaine Fuchs, PhD, Rebecca C. Lancefield Professor, Laboratory of Mammalian Cell Biology & Development, Howard Hughes Medical Investigator, Rockefeller University, will share this year's prize.

Their work pioneered innovative technologies that explain the molecular underpinnigns of skin stem cells and inherited skin disorders, including cancers and some birth defects.

"Taken together, the research of Dr. Green and Dr. Fuchs has expanded medicine's ability to diagnose and understand the basis of many skin disorders, from cancer to inherited disorders to severe burns," said Joseph Leigh Simpson, MD, senior vice president for Research and Global Programs at the March of Dimes. "Their work has saved the lives of thousands of burn patients and we hope their work with skin stem cells will lead to new ways to prevent and treat birth defects."

Dr. Green and Dr. Fuchs have worked closely together. Dr. Fuchs is a former postdoctoral fellow in Dr. Green's lab, and throughout their careers they shared their scientific findings. Many of their findings have been translated into specific treatments.

Dr. Fuchs uncovered the genetic basis of blistering skin diseases and deciphered the characteristics of skin stem cells that allow them to develop into distinct tissues and organs. She also pioneered the use of reverse genetics, which studies protein functions and then determines what diseases occur when the proteins malfunction. She studies how skin stem cells become activated to form hair and skin, how they adapt to heal wounds, and how mutations in the activation process can lead to skin cancers, such as pilomatrichomas and squamous cell carcinomas. Her pioneering work holds promise for possible therapies for baldness.

Dr. Green, considered a founding father of regenerative medicine, developed a permanent skin restoration treatment that has saved the lives of thousands of burn victims. He previously developed the first therapeutic use of cells grown in a lab. His worked laid the foundation for the discovery of genes that are responsible for genetic skin defects. He discovered that hybrid human and mouse cells lost their human chromosomes, leading to the methods used today for gene mapping.

Dr. Green and Dr. Fuchs will receive the Prize at a gala black-tie dinner and ceremony at the Fairmont Copley Plaza. They will deliver the Seventeenth Annual March of Dimes Prize Lectures at the Hynes Convention Center during the Pediatric Academic Societies annual meeting. CBS sportscaster Greg Gumbel, member of the March of Dimes national Honorary Board of Trustees, will host the award ceremony.

Individuals who receive the March of Dimes Prize are leaders in the field of developmental biology. Their pioneering research offers hope for prevention and treatments for some of the most serious birth defects and other human diseases.

The March of Dimes Prize in Developmental Biology has been awarded annually since 1996 to investigators whose research has profoundly advanced the science that underlies the understanding of birth defects. The March of Dimes Foundation created the Prize as a tribute to Dr. Jonas Salk shortly before his death in 1995. Dr. Salk received Foundation support for his work to create a polio vaccine. The prize is a cash award of $250,000 and a silver medal in the design of the Roosevelt dime, in honor of President Franklin D. Roosevelt, who founded the March of Dimes.

In its 17-year history, the March of Dimes Prize in Developmental Biology has been the crowning glory of a distinguished research career or a stepping stone on the path toward future honors for researchers. In fact, five past March of Dimes Prize recipients have gone on to win a Nobel Prize.


'/>"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Foundation
Source:Eurekalert

Related biology news :

1. Far-reaching genetics topics to be addressed: 2009 Annual Clinical Genetics Meeting, March 25-29
2. March launch planned for ESAs gravity mission
3. March of Dimes provides $2.7 million in new funding for preterm birth research
4. Penguins marching into trouble
5. Public Policy Center hosts flood symposium March 10-12
6. BioScience tip sheet, March 2009
7. Story tips from the Departments of Energys Oak Ridge National Lab -- March 2009
8. News from the March 2009 Journal of the American Dietetic Association
9. Prominent climate researcher to speak at UH on global warming March 5
10. AGU journal highlights -- March 12, 2009
11. Science returns to the Capitol Hill spotlight at March 24 exhibition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/1/2016)... Feb. 1, 2016  Wocket® smart wallet ( www.wocketwallet.com ) announces the ... Joey Fatone . Las Vegas , where ... --> Las Vegas , where Joey appeared at ... The new video ad was filmed at the Consumer Electronics Show (CES2016) ... Wocket booth to meet and greet fans. --> ...
(Date:1/27/2016)... 27, 2016  Rite Track, Inc. a leading semiconductor ... West Chester, Ohio announced today the acquisition ... based in Austin, Texas , will ... provide modifications, installations and technical support offerings for TEL ... PLUS, commented, "PLUS has provided world class service including ...
(Date:1/25/2016)... Software, the world-leading supplier of image data management solutions ... data management solution OMERO Plus for the newly established ... Photo - http://photos.prnewswire.com/prnh/20160125/325328LOGO ... analysis measures the characteristics and behavior of cells, tissues ... as health and disease, the presence or absence of ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... 8, 2016 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or ... finalists for clean technology companies in the TSX Venture 50 ... companies listed on the TSX Venture Exchange, in each of ... clean technology & life sciences, diversified industries and technology ... to return on investment, market cap growth, trading volume and ...
(Date:2/8/2016)... -- --> --> ... company developing next generation cancer therapeutics that are ... chairman emeritus of Tata Sons Limited, Mr Ratan ... part of the first close of Invictus,s Series ... and Aarin Capital. http://photos.prnewswire.com/prnh/20150923/766442 ) , ...
(Date:2/8/2016)... Md. , Feb. 8, 2016  BioElectronics ... consumer medical devices, announced today that it is ... administrative proceedings from the Securities and Exchange Commission ... Richard Staelin , Chairman of the Board of ... Professor of Business Administration at The Fuqua School ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... of Semantic Graph Database technology, today announced the availability of AllegroGraph 6, the ... through the Cloudera Certified Technology Program (CCPT). AllegroGraph is the first ...
Breaking Biology Technology: