Navigation Links
Mapping the brain: New technique poised to untangle the complexity of the brain
Date:4/10/2011

p in visual hierarchy, some neurons respond to more complex visual features such as faces: lesions to this area of the brain can prevent people from being able to recognise faces, even though they can recognise individual features such as eyes and the nose, as was famously described in the book The Man Who Mistook Wife for a Hat by Oliver Sachs.

In a study published online today in the journal Nature, the team at UCL describe a technique developed in mice which enables them to combine information about the function of neurons together with details of their synaptic connections.

The researchers looked into the visual cortex of the mouse brain, which contains thousands of neurons and millions of different connections. Using high resolution imaging, they were able to detect which of these neurons responded to a particular stimulus, for example a horizontal edge.

Taking a slice of the same tissue, the researchers then applied small currents to a subset of neurons in turn to see which other neurons responded and hence which of these were synaptically connected. By repeating this technique many times, the researchers were able to trace the function and connectivity of hundreds of nerve cells in visual cortex.

The study has resolved the debate about whether local connections between neurons are random in other words, whether nerve cells connect sporadically, independent of function or whether they are ordered, for example constrained by the properties of the neuron in terms of how it responds to particular stimuli. The researchers showed that neurons which responded very similarly to visual stimuli, such as those which respond to edges of the same orientation, tend to connect to each other much more than those that prefer different orientations.

Using this technique, the researchers hope to begin generating a wiring diagram of a brain area with a particular behavioural function, such as the visual cortex. This knowl
'/>"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Chemical equator discovery will aid pollution mapping
2. Mapping a clan of mobile selfish genes
3. New rainforest mapping technology gets huge support
4. Studies offer guide as protein interaction mapping comes of age
5. Neural mapping paints a haphazard picture of odor receptors
6. Plant gene mapping may lead to better biofuel production
7. A Canada-wide technology platform for mapping the human interactome
8. Scientists take early steps toward mapping epigenetic variability
9. First phase of pan-tropical forest mapping debuting at COP15
10. AgriLife scientists do groundwork for genetic mapping of algae biofuel species
11. Genome mapping technique speeds process of finding specific genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... - Washington State University researchers have developed a unique ... power waste cleanup in rural areas. , The ... an inexpensive and quick way to clean up waste ... while reducing pollution. , Professor Haluk Beyenal and ... Engineering and Architecture discuss the system in the online ...
(Date:9/18/2014)... novel robotic system that can operate inside the bore ... part of a biomedical research partnership program at Brigham ... determining if the robot, in conjunction with real-time MRI ... less costly, and less discomforting for the patient. The ... cancer therapies with greater precision. , Developed by a ...
(Date:9/18/2014)... language is unique to humans. "The genetic changes that ... evolution to make this possible are largely unknown, but ... says Wolfgang Enard, Professor of Anthropology and Human Biology ... biological basis of language Enard has now taken an ... undertaken in collaboration with scientists at several universities, including ...
Breaking Biology News(10 mins):Researchers develop unique waste cleanup for rural areas 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5Language evolution: Quicker on the uptake 2Language evolution: Quicker on the uptake 3
... Calif., May 9, 2012 Human cells are thought to ... that help determine which genes are turned on or off ... normal cellular function, but they can also contribute to human ... promote cell survival. But to better understand how miRNAs influence ...
... to understand how the aging process affects the brain ... older adults. "Everybody ages differently. By looking at ... health, we begin to understand that preventable factors may ... University psychology doctoral student Andrew Bender, lead author of ...
... May 9, 2012 (Bronx, NY) Researchers at ... University have discovered a molecule that inhibits the action ... in the growth, maintenance and repair of reproductive tissues ... The molecule, discovered in animal studies, could lead to ...
Cached Biology News:It's a trap! New laboratory technique captures microRNA targets 2WSU researchers say genes and vascular risk modify effects of aging on brain and cognition 2WSU researchers say genes and vascular risk modify effects of aging on brain and cognition 3Molecule found that inhibits estrogen, key risk factor for endometrial and breast cancers 2
(Date:9/18/2014)... , Sept. 18, 2014 About POCT ... is performed outside a clinical laboratory. It helps ... administrating appropriate treatments and medication. POCT is gaining ... of lifestyle diseases such as diabetes, heart disease, ... POCT devices are standardized to minimize errors during ...
(Date:9/18/2014)... Bryan-College Station, Texas (PRWEB) September 18, 2014 ... University System Chancellor John Sharp, Texas A&M Health ... from the U.S. Department of Health and Human ... GSK today dedicated a national pandemic influenza vaccine ... will serve as an anchor for the Texas ...
(Date:9/18/2014)... , Sept. 18, 2014 Research ... "Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, ... report to their offering. The global ... CAGR of 22.7% from 2014 to 2019. Factors such ... growing adoption of companion diagnostics by the pharmaceutical industry, ...
(Date:9/18/2014)... - Oncothyreon Inc. (NASDAQ: ONTY ) today ... underwritten offerings of 10,000,000 shares of its Common Stock ... share, for expected gross proceeds of $20 million and ... at a price to the public of $2,000.00 per ... share of Series A Convertible Preferred Stock is non-voting ...
Breaking Biology Technology:POCT Market in China 2014-2018 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 3Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 4Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 3Oncothyreon Prices $40 Million Concurrent Public Offerings of Common Stock and Preferred Stock 2Oncothyreon Prices $40 Million Concurrent Public Offerings of Common Stock and Preferred Stock 3
... recruiting tech talent and investors to state, ... Enterprise,Corporation (KTEC) announced today a "Come Home to ... technology professionals,and investors to Kansas. Partners in this ... Bioscience Authority, the Kansas,Bioscience Organization and the KTEC ...
... Hologic, Inc.,(Nasdaq: HOLX ), a diversified ... and interventional devices dedicated to,serving the healthcare needs ... quarter fiscal 2008 operating results on Thursday, January ... the release, management will,host a conference call on ...
... and Webcast Scheduled for Tuesday, February 5, SAN ... ) announced today that the Company will report its ... market closes,on Tuesday, February 5, 2008. Neurocrine will then ... financial results and provide a Company,update Tuesday afternoon, February ...
Cached Biology Technology:'Come Home to Kansas' Announced by KTEC 2Hologic, Inc. to Release First Quarter Fiscal 2008 Operating Results Thursday, January 31st Before Market Opens 2Neurocrine Biosciences Announces Conference Call and Webcast to Present Fourth Quarter and Year End 2007 Financial Results 2