Navigation Links
Map of herpes virus protein suggests a new drug therapy
Date:7/6/2010

ll," said Jeremy M. Berg, PhD, director of the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health.

"We hope that determining the structure of this essential piece of the herpes virus cell-entry machinery will help us answer some of the many questions about how herpes virus initiates infection. Knowing the structures of cell-entry proteins will help us find the best strategy for interfering with this pervasive family of viruses," said first author Tirumala K. Chowdary, PhD, a postdoctoral associate in the department of molecular biology and microbiology at TUSM and member of Heldwein's lab.

Currently, there is no cure for herpes viruses. Upon infection, the viruses remain in the body for life and can stay inactive for long periods of time. When active, however, different herpes viruses can cause cold sores, blindness, encephalitis, or cancers. More than half of Americans are infected with herpes simplex virus type 1 (HSV-1), which causes cold sores, by the time they reach their 20s. Currently, about one in six Americans is infected with herpes simplex virus type 2 (HSV-2), the virus responsible for genital herpes. Complications of HSV-2, a sexually-transmitted disease, include recurrent painful genital sores, psychological distress, and, if transmitted from mother to child, potentially fatal infections in newborn infants.

Heldwein teamed up with colleagues at University of Pennsylvania and used x-ray crystallography along with cell microscopy techniques to study the structure and function of this cell-entry protein complex in HSV-2. Heldwein is currently developing a molecular movie that illustrates how herpes virus enters the cell.


'/>"/>

Contact: Siobhan Gallagher
617-636-6586
Tufts University, Health Sciences
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Sleeping Beauty hooks up with herpes to fight brain disease
2. Herpes virus: To vaccinate or not to vaccinate
3. Potential new herpes therapy studied
4. Herpes drug inhibits HIV in patients infected with both viruses
5. Herpes virus link to complications in pregnancy
6. Penn researchers shine the light of venus to learn how the herpes virus invades cells
7. Wallabies and bats harbor fossil genes from the most deadly family of human viruses
8. Discovery of a hepatitis C-related virus in bats may reduce outbreaks in humans
9. Nutrients, viruses and the biological carbon pump
10. Virus explorers probe inner workings of the brain
11. 2009 H1N1 vaccine protects against 1918 influenza virus
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Map of herpes virus protein suggests a new drug therapy
(Date:2/5/2015)... Jan. 28, 2015 NXT-ID, Inc. (NASDAQ: ... a biometric authentication company focused on the growing mobile ... RedChip Global Online CEO Conference on January 29 th ... Gino Pereira , CEO of NXT-ID will present and ... the Wocket smart wallet and its full suite of ...
(Date:2/5/2015)... , Feb. 3, 2015 Despite a ... from industries such as consumer electronics, automotive, storage ... surface mount technology (SMT) screen printers. Innovations in ... control will push the adoption curve up. Meanwhile, ... steady as glue dispensers are indispensable in the ...
(Date:1/22/2015)... TORONTO , Jan. 13, 2015 /PRNewswire/ - Today, FindBiometrics, the ... announced the launch of its new website design. ... in its infancy", says Peter O,Neill , founder and ... ever, the industry needs involvement from the key players on ...
Breaking Biology News(10 mins):CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 2CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 3End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2
... F. Laurance, senior staff scientist at the Smithsonian Tropical ... the Institute and Biodiversity Chair at the H. John ... have won the coveted 2008 BBVA Foundation Frontiers of ... 30 Jan. 2009 in Madrid, Spain. , ...
... deposited iron in the Southern Ocean has filled in ... in locking atmospheric carbon dioxide (CO2) in the ocean. ... Raymond Pollard of the National Oceanography Centre, Southampton, and ... Hole Oceanographic Institution (WHOI), found that natural iron fertilization ...
... many studies refuting the claim of a link between vaccines ... issue of Clinical Infectious Diseases and now available ... epidemiological and biological studies refute these claims. "When one ... springs up to take its place," said study author Paul ...
Cached Biology News:Smithsonian scientists receive coveted BBVA Ecology and Conservation Award 2Ocean islands fuel productivity and carbon sequestration through natural iron fertilization 2Ocean islands fuel productivity and carbon sequestration through natural iron fertilization 3Vaccines and autism: Many hypotheses, but no correlation 2
(Date:3/2/2015)... MIAMI (PRWEB) March 02, 2015 ... a newly formed alliance with Shenzhen HANK Bioengineering ... M.D., Ph.D. The alliance will establish a stem ... Guangdong Province, China in September 2015. , Shenzhen ... by Zhang, an award-winning scientist, microbiologist and virologist, ...
(Date:2/27/2015)... Immunovaccine Inc. (“Immunovaccine” or the “Company”) (TSX: ... release disseminated this morning by PR Web, and redistributed ... release states that Immunovaccine has entered into a co-development ... did not originate from Immunovaccine and there is no ... Please note that all official statements by Immunovaccine ...
(Date:2/27/2015)... , Feb. 27, 2015 Research and Markets ... "Global Market Report of Trypsin" report to their offering. ... 9002-07-7) aims at providing comprehensive data on Trypsin globally and ... , North America , Latin ... close attention to Trypsin This report focuses on ...
(Date:2/27/2015)... , Feb. 27, 2015  Pfenex Inc. (NYSE ... development of biosimilar therapeutics, today announced that it will ... Marriott Marquis on March 2 nd at 3pm ... on a panel discussing the current state of the ... Biosimilars . For more information on ...
Breaking Biology Technology:Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China 2Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China 3Immunovaccine Disclaims Hoax Press Release 2Global Market Report of Trypsin 2014-2018 2
... managed, with the help of an advanced X-ray flash, to ... that has been recognised by the journal Science . ... home to one of the world,s most advanced particle accelerators, ... and study life,s tiniest components: atoms, molecules and proteins. ...
... PLYMOUTH MEETING, Pa. , May 10 /PRNewswire-Asia-FirstCall/ -- ... announced,financial results for the first quarter ended March 31, 2010 . ... ... was a,quarter of successful management transition at Sunstone. We replaced senior,managers including ...
... Fla. , May 10 Dyadic International, Inc. ... today that its President and Chief Executive Officer, Mark ... Renshaw 6th Annual Global Healthcare Conference in London, England ... 11:05 a.m. local time ( 6:05 a.m. EDT ). ...
Cached Biology Technology:BMP Sunstone Reports First Quarter 2010 Financial Results 2BMP Sunstone Reports First Quarter 2010 Financial Results 3BMP Sunstone Reports First Quarter 2010 Financial Results 4BMP Sunstone Reports First Quarter 2010 Financial Results 5BMP Sunstone Reports First Quarter 2010 Financial Results 6BMP Sunstone Reports First Quarter 2010 Financial Results 7BMP Sunstone Reports First Quarter 2010 Financial Results 8BMP Sunstone Reports First Quarter 2010 Financial Results 9BMP Sunstone Reports First Quarter 2010 Financial Results 10BMP Sunstone Reports First Quarter 2010 Financial Results 11BMP Sunstone Reports First Quarter 2010 Financial Results 12Dyadic International to Present at Rodman & Renshaw 6th Annual Global Healthcare Conference 2
... automated microplate strip washer for 96- and 384-well ... strip washing capability, the Columbus combines high flexibility ... , Features ,Key features ... or 16 channels, crosswise aspiration, overflow and bottom ...
... solution for all plate washing needs in both ... ,The PW 384 provides an excellent solution for ... Discovery (Assay development, Screening or Lead Optimization) and ... ,The PW 384 has set a standard for ...
... Protein:Protein Interaction Reagent A powerful new ... gained traction as an in vitro method ... of publications feature the exclusive Pierce ProFound ... a variety of issues relating to protein ...
... compact benchtop and stackable multi-function incubator. ... a large display screen to accurately ... circulation inside to evenly distribute temperature ... easily calibrated from the microprocessor controller. ...
Biology Products: