Navigation Links
Manure management reduces levels of antibiotics and antibiotic resistance genes
Date:11/28/2007

MADISON, WI, November 26, 2007- Antibiotic resistance is a growing human health concern. Researchers around the globe have found antibiotics and other pharmaceuticals to be present in surface waters and sediments, municipal wastewater, animal manure lagoons, and underlying groundwater. In a recent article in the November-December issue of Journal of Environmental Quality, researchers at Colorado State University (CSU) describe a study to find out if animal waste contributes to the spread of antibiotics and antibiotic resistance genes (ARG), and if they can be reduced by appropriate manure management practices.

In the study, funded by the USDA Agricultural Experiment Station at CSU and the National Science Foundation (NSF), researchers investigated the effects of manure management on the levels of antibiotics and ARG in manures. The study was conducted at two scales. In the pilot-scale experiment, horse manure was spiked with the antibiotics chlortetracycline, tylosin, and monensin and compared to horse manure that was not spiked with antibiotics to determine the response of ARG in unacclimated manures. In the large-scale experiment, dairy manure and beef feedlot manure, which were already acclimated to antibiotics, were monitored over time.

The manures were subjected to high-intensity management (HIM-amending with leaves and alfalfa, watering, and turning) and low-intensity management (LIM-no amending, watering, and turning) for six months. During this time, the levels of antibiotics were monitored using high-performance liquid chromatography (HPLC) and tandem mass spectrometry (MS/MS). In addition, two types of ARG that confer resistance to tetracycline, tet(W) and tet(O), were monitored using quantitative polymerase chain reaction (Q-PCR).

In the pilot study, chlortetracycline, tylosin, and monensin all dissipated more rapidly in the HIM-manure than in the LIM-manure. In the large-scale study, feedlot manure initially had higher concentrations of the several tetracycline antibiotics than the dairy manure. After four months of treatment, tet(W) and tet(O) decreased significantly in dairy manure, but two more months of treatment were necessary for similar reductions of ARG in the feedlot manures.

The results showed that HIM was more effective than LIM at increasing the rate of antibiotic dissipation, but it was not a significant factor in reducing the levels of ARG. The length of treatment time was the main factor in reducing the levels of both antibiotics and ARG. For manures with initially high levels of antibiotics, treatment times of at least six months may be necessary for a significant reduction in levels of antibiotics and ARG. The results also provided evidence that ARG may be present for extended time periods even after antibiotics have fully dissipated.

Scientists at Colorado State University are continuing research in this area by examining full-scale local on-farm waste management practices. Together this research will lead to a better understanding of possible ARG mitigation strategies so that best management practices can be developed to reduce the effects that animal waste may have on the spread of ARG.


'/>"/>

Contact: Sara Uttech
suttech@agronomy.org
608-268-4948
American Society of Agronomy
Source:Eurekalert

Related biology news :

1. Central targets may hinder wider waste management objectives
2. Upgraded IMG 2.3 Data Management System released by DOE JGI to eager user community
3. Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management
4. Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management
5. Parus Interactive Awarded Patent for Speech-Activated Remote System Management
6. Mosaic Intelligent Video Management System: Video Surveillance Just Got Smarter
7. Secure Services Corp. Achieves Milestone in United States Identity Protection with the Launch of the SSC SHAPE Card Management Solution
8. Fireproofing homes dramatically reduces forest fire size, according to new study
9. Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients
10. Exercise improves thinking, reduces diabetes risk in overweight children
11. Low levels of key protein may indicate pancreatic cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2016)... , June 16, 2016 ... is expected to reach USD 1.83 billion by ... View Research, Inc. Technological proliferation and increasing demand ... are expected to drive the market growth. ... The development of advanced multimodal techniques ...
(Date:6/9/2016)... in attendance control systems is proud to announce the introduction of fingerprint attendance control ... right employees are actually signing in, and to even control the opening of doors. ... ... ... Photo - ...
(Date:6/7/2016)... 7, 2016  Syngrafii Inc. and San Antonio ... that includes integrating Syngrafii,s patented LongPen™ eSignature "Wet" ... collaboration will result in greater convenience for SACU ... while maintaining existing document workflow and compliance requirements. ... Highlights: ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... ... 02, 2016 , ... Robots will storm the Prudential Center in Boston, MA ... event, which is held on the United Nations International Day of Persons with Disabilities, ... the workplace. Suitable Technologies is partnering with NTI to showcase how technology can help ...
(Date:11/30/2016)... , ... November 30, 2016 , ... ... moving magnet Voice Coil Actuator with a flexure design that ensures high alignment ... with cost-effective pricing and is ideally suited where extreme precision is required, such ...
(Date:11/30/2016)... Biotest Pharmaceuticals Corporation (BPC), a leading manufacturer ... addition of its newest plasma collection center located at ... The 15,200 square foot state-of-the-art facility officially opened its ... the total number of BPC,s plasma collection centers to ... Chief Executive Officer said "We are pleased to become ...
(Date:11/30/2016)... DIEGO and BEIJING , ... a leading commercial provider of genomic services and solutions ... announced today that it has completed a USD $75 ... Merchants Bank Co., Ltd.,s CMB International Capital Management ( ... Innovation Investment Management Co., Ltd. ("SDIC Innovation") and Shanghai ...
Breaking Biology Technology: