Navigation Links
Manufacturing microscale medical devices for faster tissue engineering
Date:11/2/2011

, small 2PP building blocks can create a richly detailed design, but if you want a large structure, like a tissue scaffold that could mimic natural body parts, it can take a long time to lay all the pieces together.

"Blood vessel networks can be several centimeters in length, but walls of the smallest branches (capillaries) are only a few micrometers thick. The same applies with any tissue. Many tissues may be large, but they all have important features on the microscale," says team member Shaun Gittard of the LZH. The team notes that using conventional 2PP to manufacture the tissue scaffolds for such structures could be prohibitively slow. They address the problem by using a computer-controlled hologram to split the 2PP laser into multiple beams, creating up to 16 different focus points that can work simultaneously.

"As an example, take the time for fabricating a single layered, 1-millimeter square with 100 nanometer resolution," the authors write. "With conventional single-focus 2PP at one millimeter per second, the fabrication time would be 2 hours and 47 minutes. In contrast, with 16 foci this same area could be scanned in merely 10 minutes." Or, in other words, many foci make light work.

The team first tested their multiple foci system by creating 16 miniature Venus statues, each so small as to be invisible to the human eye (see figure 1). "The Venus is kind of a logo of our research group," says Gittard. "We have used it as a familiar demonstration structure for various fabrication techniques."

In addition to replicas of classic Greek artwork, the team also used the new technique to manufacture cylindrical tissue scaffolds (see figures 2) and an array of microneedles. Less than a half millimeter wide, rocket-shaped microneedles can be used to provide painless injections or take blood samples, notes Gittard (see figure 3). "One of the biggest promises in the future is real-time, pain-free glucose sensing and insulin delive
'/>"/>

Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. ExcellGene SA first company to offer contract manufacturing in 250 Liter OrbShake bioreactor
2. Louisiana Techs Institute for Micromanufacturing to collaborate with colleagues in the arts
3. Manufacturing antibodies
4. Semiconductor Manufacturing International Corporation: Announcement of 2009 Annual Results
5. Fly eye paves the way for manufacturing biomimetic surfaces
6. Discovery of source of glycogen manufacturing errors sheds light on fatal disease
7. Advance in microchannel manufacturing opens new industry applications
8. Reportlinker Adds Enzymes in Drug Manufacturing
9. New process for manufacturing nanocellulose recognized with the Empa Research Award
10. NSF funds states first imaging system for UAB microscale research lab
11. Quartz crystal microbalances enable new microscale analytic technique
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Manufacturing microscale medical devices for faster tissue engineering
(Date:12/17/2014)...  Automation is fundamentally transforming the travel experience ... international borders. Over the past decade, ePassports, biometric ... travelers to self process through border control via ... an increasing number of airports, seaports, and land ... to Maxine Most , Principal at Acuity ...
(Date:12/11/2014)... 10, 2014  Data Sciences International (DSI), the ... a new series of digital telemetry implants to ... M series, part of the PhysioTel™ Digital platform, ... possible physiologic data when incorporating functional endpoints into ... to toxicology studies has evolved from short ECG ...
(Date:12/10/2014)... Research and Markets ( http://www.researchandmarkets.com/research/xclcvw/biometrics_market ... "Biometrics Market in Japan 2014-2018" report to ... The integration of biometrics and ... and upgradation of the driver,s license is one ... Besides the aforementioned projects, biometrics is being used ...
Breaking Biology News(10 mins):Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2New telemetry implants expected to change how large animal toxicology studies are conducted 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... The National Science Foundation (NSF) recently awarded $55.5 ... Engineering Research Centers (ERCs) that will advance interdisciplinary ... Over the next five years, these Nanosystems ... innovations that address significant societal issues, such as ...
... more severe in the Southwest, trees are increasingly up ... middle elevations, University of Arizona researchers report in a ... of Geophysical Research Biogeosciences ., Lead author Jeremy Weiss, ... geosciences, said: "We know the climate in the Southwest ...
... human liver-chimeric mouse model developed at Oregon Health & Science ... at Seattle Biomedical Research Institute that will greatly accelerate studies ... The study findings are published online in the Journal ... in "Scientific Show Stoppers" on the JCI blog. ...
Cached Biology News:Engineering research centers awarded $55.5 million to innovate in nanoscale science and engineering 2Engineering research centers awarded $55.5 million to innovate in nanoscale science and engineering 3Droughts are pushing trees to the limit 2Droughts are pushing trees to the limit 3Droughts are pushing trees to the limit 4'Humanized' mice developed at OHSU enable malaria research breakthrough at Seattle BioMed 2'Humanized' mice developed at OHSU enable malaria research breakthrough at Seattle BioMed 3
(Date:12/19/2014)... MA (PRWEB) December 18, 2014 LayerBio ... for ophthalmology and wound care. The National Eye Institute ... awarded LayerBio a Phase I SBIR grant to develop ... Cataracts are the most common cause of vision loss ... of blindness worldwide. According to Dr. Ken Mandell, LayerBio’s ...
(Date:12/19/2014)... 18, 2014 iLab Solutions, the global ... of Siri Bryant as the new Director of Institutional ... Core Implementations. These two new leadership positions were created ... by ensuring that iLab continues to meet the needs ... four years, iLab has been deployed at over 450 ...
(Date:12/19/2014)... San Diego, CA (PRWEB) December 18, 2014 ... announces a limited time special on Sartorius Biohit ... 1 Free on mLINE pipettes, Picus Electronic Pipette Trade-in ... recommended by Health and Safety officers around the world. ... repetitive manual pipetting. Other features include:, , ...
(Date:12/19/2014)...   ISN has released its third annual ... publication series. With data aggregated from over eight ... within its online contractor management platform, ISNetworld, this three-part ... (KPI) statistics. The Contractor ... is available in two industry specific volumes: Oil ...
Breaking Biology Technology:LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3
... There are many municipalities around the Midwest looking for ... into the traditional approaches of bringing in developers to ... trying to entice businesses with tax incentives and reduced ... , ,This is a common practice with even large ...
... , Wis. - Software piracy ... track it are getting better at cracking down, and violators ... one in five software programs in use in the United ... are increasingly taking measures to protect their assets, primarily through ...
... technology consolidation projects bound to be expensive, problematic, and ... of Wisconsin, has indicated the problems Wisconsin is having ... projects. He has plenty of support on that point, ... implementation delays, and outright failures really inevitable? , ,Christopher ...
Cached Biology Technology:Electronic signs for municipalities: Las Vegas or lost revenues? 2Electronic signs for municipalities: Las Vegas or lost revenues? 3Electronic signs for municipalities: Las Vegas or lost revenues? 4Companies are still taking software license 2Companies are still taking software license 3State IT failures are not inevitable 2State IT failures are not inevitable 3State IT failures are not inevitable 4State IT failures are not inevitable 5
... The RapidPlate 96/384 workstation offers precise ... highly scalable format. Utilizing 100ul and 200ul ... head delivers excellent accuracy and precision across ... position rotary deck includes two positions that ...
... you reduce the chance of error. Thats ... Developed using Beckman Coulters extensive experience in ... technology, the CEQ 8000 is a fully ... fills the capillary array with a patented ...
... The AquaMax DW4 liquid handling system from ... washing all in one instrument. The system ... dispensing and plate washing96-, 384- and 1536-welland ... washing. AquaMax DW4 has been optimized to ...
... Software enables you to identify over ... can distinguish protein isoforms, protein subsets, ... also visualize peptide-protein associations and relationships ... protein identification and relative protein expression ...
Biology Products: