Navigation Links
Manufacturing microscale medical devices for faster tissue engineering
Date:11/2/2011

, small 2PP building blocks can create a richly detailed design, but if you want a large structure, like a tissue scaffold that could mimic natural body parts, it can take a long time to lay all the pieces together.

"Blood vessel networks can be several centimeters in length, but walls of the smallest branches (capillaries) are only a few micrometers thick. The same applies with any tissue. Many tissues may be large, but they all have important features on the microscale," says team member Shaun Gittard of the LZH. The team notes that using conventional 2PP to manufacture the tissue scaffolds for such structures could be prohibitively slow. They address the problem by using a computer-controlled hologram to split the 2PP laser into multiple beams, creating up to 16 different focus points that can work simultaneously.

"As an example, take the time for fabricating a single layered, 1-millimeter square with 100 nanometer resolution," the authors write. "With conventional single-focus 2PP at one millimeter per second, the fabrication time would be 2 hours and 47 minutes. In contrast, with 16 foci this same area could be scanned in merely 10 minutes." Or, in other words, many foci make light work.

The team first tested their multiple foci system by creating 16 miniature Venus statues, each so small as to be invisible to the human eye (see figure 1). "The Venus is kind of a logo of our research group," says Gittard. "We have used it as a familiar demonstration structure for various fabrication techniques."

In addition to replicas of classic Greek artwork, the team also used the new technique to manufacture cylindrical tissue scaffolds (see figures 2) and an array of microneedles. Less than a half millimeter wide, rocket-shaped microneedles can be used to provide painless injections or take blood samples, notes Gittard (see figure 3). "One of the biggest promises in the future is real-time, pain-free glucose sensing and insulin delive
'/>"/>

Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. ExcellGene SA first company to offer contract manufacturing in 250 Liter OrbShake bioreactor
2. Louisiana Techs Institute for Micromanufacturing to collaborate with colleagues in the arts
3. Manufacturing antibodies
4. Semiconductor Manufacturing International Corporation: Announcement of 2009 Annual Results
5. Fly eye paves the way for manufacturing biomimetic surfaces
6. Discovery of source of glycogen manufacturing errors sheds light on fatal disease
7. Advance in microchannel manufacturing opens new industry applications
8. Reportlinker Adds Enzymes in Drug Manufacturing
9. New process for manufacturing nanocellulose recognized with the Empa Research Award
10. NSF funds states first imaging system for UAB microscale research lab
11. Quartz crystal microbalances enable new microscale analytic technique
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Manufacturing microscale medical devices for faster tissue engineering
(Date:4/14/2015)... , April 14, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, ... for the 2015 New York Design Awards under the ... New York City Design Awards are part of a ... over 2,500 ratings from the marketplace, industry and judging ...
(Date:4/9/2015)... Calif. , April 9, 2015 Synaptics ... interface solutions, announced today that it will report financial ... Thursday, April 23, 2015, after the close of market. ... analysts and investors at 2:00 p.m. PT (5:00 p.m. ... To participate on the live call, analysts ...
(Date:4/2/2015)... , April 2, 2015 At its 2015 ... Lake City , the American College of Medical ... new directors to its Board.  Members of the ACMG ... and for forming and advancing its policies and programs. ... profession. "It,s an eventful time in medical ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3Synaptics to Report Third Quarter Results on April 23 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8
... Dana-Farber Cancer Institute researchers have identified a molecular mechanism ... how consuming foods rich in saturated fats and trans-fatty ... and increases one's risk of heart disease and certain ... scientists led by Bruce Spiegelman, PhD, report that the ...
... patients with high-risk breast cancer treated with radical mastectomy ... to better survival outcomes with few long-term toxic effects, ... which appears in the January 19 issue of the ... Columbia randomized radiation therapy trial was designed to determine ...
... recent U.S. study, investigators in Japan found no association ... of high blood pressure, as reported in the March ... available online. , The researchers reported that they were ... known as the Kaposi's sarcoma virus, in the lungs ...
Cached Biology News:Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats 2Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats 3Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down 2Association of herpesvirus with lung disorder questioned 2
(Date:4/24/2015)... April 24, 2015 Seoul Semiconductor ... for various applications in the lighting market. ... installations of this technology in emerging markets such ... a wide range of applications such as streetlight ... decorative lighting. , First launched in 2005 the ...
(Date:4/23/2015)... , April 23, 2015 BioTE Medical President ... book "Age Healthier Live Happier - Avoiding Over-Medication through ... Age Management Medicine Group Conference at JW Marriott / ... ",Age Healthier Live Happier, is a welcomed ... over-medication and searching for a higher quality of life ...
(Date:4/23/2015)... LAKE FOREST, Calif. , April 23, 2015 ... provider of advanced cryogenic logistics solutions for the ... has further established its cryogenic logistics solutions within ... customer agreement with Yancey Farms to support the ... top German Sport horse Stallions. ...
(Date:4/23/2015)... April 23, 2015  Metanome, Inc., an industry ... company has changed its name to Diversigen, Inc.  ... as the single commercial source for the myriad ... on the diverse opportunities of the microbiome.  From ... accepts – including those that are difficult to ...
Breaking Biology Technology:Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 3Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Metanome Announces Corporate Name Change to Diversigen 2
... Wis. - Lucigen Corp . and ... giving Lucigen exclusive worldwide rights to manufacture and sell ... , ,Under the agreement, Imaxio will retain the right ... applications, but Lucigen will provide the cells to commercial ...
... - It has yet to turn a profit, and it ... scope, but the decision by Madison research tool manufacturer NimbleGen ... to $75 million is the latest bit of evidence that the ... continues a pattern of growth and visibility for NimbleGen, which ...
... Alfalight , a manufacturer of high-power diode lasers, has ... million from the U.S. Army Research Laboratory . ... suitable for pumping high-power, fiber-laser systems, developed in conjunction ... commercial products. , ,Manoj Kanskar, vice president of research ...
Cached Biology Technology:Lucigen Corp. enters global licensing agreement 2IPO-bound NimbleGen traveling in fast company 2IPO-bound NimbleGen traveling in fast company 3IPO-bound NimbleGen traveling in fast company 4
... White solid. PROTECT FROM LIGHT. ... water soluble pyrimidinone compound that acts as ... of PARP (IC 50 = 200 ... rmPARP2, respectively) with little activity against the ...
... speed, timer, SB3, Fully adjustable mixing angle, ... holders to hold a number of different ... ideal for aerating cultures, keeping biological samples ... The rotator can be used in incubators ...
...
... The DNA Engine Opticon 2 real-time ... of LEDs for fluorescence excitation (470-505 nm) ... (523-543 nm, 540-700 nm). The Opticon 2 ... thermal cycler, which includes a thermal gradient ...
Biology Products: