Navigation Links
Mannotriose promotes survival of hippocampal neurons
Date:1/6/2014

The main component of the Chinese herb Rehmannia, mannotriose, can improve learning and memory. Dr. Lina Zhang and colleagues from Shanghai University of Traditional Chinese Medicine in China used 1 10 mol/L mannotriose to treat primary hippocampal neurons insulted with 1 10 mol/L corticosterone. They found that hippocampal neuron survival rates and protein levels of glucocorticoid receptor, serum and glucocorticoid-regulated protein kinase, and brain-derived neurotrophic factor were all dramatically decreased after high-concentration corticosterone-induced injury. This effect was reversed by mannotriose, to a similar level as RU38486 and donepezil. These findings, published in the Neural Regeneration Research (Vol. 8, No. 32, 2013), indicate that mannotriose could protect hippocampal neurons from high-concentration corticosterone-induced injury. The mechanism by which this occurred was associated with levels of glucocorticoid receptor protein, serum and glucocorticoid-regulated protein kinase, and brain-derived neurotrophic factor.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Gene promotes 1 in 100 of tumors
2. Treadmill step training promotes motor function after incomplete spinal cord injury
3. Dysfunctional chemokine receptor promotes candidiasis
4. Testosterone promotes reciprocity in the absence of competition
5. Environmental complexity promotes biodiversity
6. Team finds gene that promotes drug resistance in cancer
7. NJIT professor promotes building material of millennium: Autoclave aerated concrete
8. Breast milk promotes a different gut flora growth than infant formulas
9. New Genetics educational resource promotes active learning
10. An economical, effective and biocompatible gene therapy strategy promotes cardiac repair
11. Single protein promotes resistance to widely used anti-estrogen drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mannotriose promotes survival of hippocampal neurons
(Date:5/6/2017)... 2017 RAM Group , Singaporean ... breakthrough in biometric authentication based on a ... to perform biometric authentication. These new sensors are based ... by Ram Group and its partners. This sensor will ... chains and security. Ram Group is a next ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced ... will feature emerging and evolving technology through ... Innovation Summits will run alongside the expo portion of ... sessions, panels and demonstrations focused on trending topics within ... advanced design and manufacturing event will take place June ...
(Date:4/11/2017)... Florida , April 11, 2017 ... a security technology company, announces the appointment of independent Directors ... Bendheim to its Board of Directors, furthering the company,s ... ... of NXT-ID, we look forward to their guidance and benefiting ...
Breaking Biology News(10 mins):
(Date:9/21/2017)... ... September 21, 2017 , ... Executives and ... world’s most progressive pharma and biotech organizations to do more clinical trials will ... biotech events in Q4. , DrugDev will demonstrate DrugDev Spark™, the world’s first ...
(Date:9/21/2017)... ... September 21, 2017 , ... ... today announced the election of Paul Hermes, Entrepreneur in Residence at Medtronic, Inc., ... Biorez has developed a proprietary, tissue-engineered scaffold for anterior cruciate ligament (ACL) reconstruction ...
(Date:9/20/2017)... Bell, PA and College Station, TX (PRWEB) , ... ... ... IPS-Integrated Project Services, LLC (IPS), a leading global provider of ... Manufacturing, Inc. the leading provider of prefabricated cleanrooms, today announced the unveiling ...
(Date:9/20/2017)... ... September 20, 2017 , ... Foresight Institute, a leading ... transformative technologies, announced the winners for the 2017 Foresight Institute Feynman Prizes.These are ... nanotechnology/molecular manufacturing. , Established in 1993 and named in honor of pioneer physicist ...
Breaking Biology Technology: