Navigation Links
Malfunction of the respiratory epithelium is a cause of allergy?
Date:4/3/2009

llergic patients but not of healthy subjects. This kind of transport mechanisms are used by several viruses and bacteria when invading the epithelium and infecting patients", explains Professor Risto Renkonen (Haartman Institute, University of Helsinki and HUSLAB, Helsinki, Finland).

A systems biological approach was used in these studies, where data obtained concomitantly by several different methods is collected into a massive data warehouse allowing one to start analyzing the roles of different proteins and their networks in the pathogenesis of allergic reactions.

Reductionistic analyses, i.e., work focusing on one or only a few molecules are gradually replaced by systems approaches. The ability to discover new, etiologically relevant disease mechanisms is the major motivation for unbiased explorative approaches. The drawback of such top-down experiments is that they are very expensive and produce much more raw data than hypothesis-derived approaches thus generating an overflow of data. However, the urgent need to develop in silico data managing and analysis environments has been recognized by several research groups and biocompanies.


'/>"/>

Contact: Professor Risto Renkonen
risto.renkonen@helsinki.fi
358-405-535-219
University of Helsinki
Source:Eurekalert

Page: 1 2

Related biology news :

1. Iron-moving malfunction may underlie neurodegenerative diseases, aging
2. Prolonged respiratory problems for oil spill clean-up volunteers
3. Research leading to tools for managing bovine respiratory disease complex
4. Veterinary college researchers explore function of biofilm in bovine respiratory disease
5. deCODE discovers cause of major subtype of glaucoma
6. Study begins to reveal clues to the cause and progression of sepsis
7. Bleeding, not inflammation, is major cause of early lung infection death
8. Gamma globulin effective in treating eye infections caused by adenoviruses
9. Hidden interactions between predators and prey: evolution causes cryptic dynamics in ecology
10. Spaceflight shown to alter ability of bacteria to cause disease
11. Grubs passion for plastic causes water loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... – High doses of fish oil supplements, rich in omega-3 ... of irregular heartbeat in which the heart can beat as ... AFFORD trial led by the Montreal Heart Institute were published ... on October 7th. , For the trial, 337 patients ... assigned to 4 grams of fish oil a day or ...
(Date:10/14/2014)... This week, an international team of researchers, led by ... in the journal Nature Genetics a brief ... 360 varieties of the tomato plant. , The C.M. ... an important role in this study by providing seed ... , This study, which builds on the first tomato ...
(Date:10/14/2014)... – Researchers from Stanford University School of Medicine have ... cells and the activation of muscle stem cells. Cells ... energy during times of nutrient deprivation. The scientists report ... protective mechanism is operational it also seems to assist ... that when stem cells emerge from a quiescent state ...
Breaking Biology News(10 mins):Autophagy helps fast track stem cell activation 2
... comforting thought unless the living thing in question is a ... developing drug resistance, outwitting immune systems, and evading cellular controls. ... perturbations such as mutations that affect the function of vital ... perform old tasks. Somehow the bad guys find ...
... The delicate lady bug in your garden could be frighteningly ... in the air, a new study concludes. The study adds ... during the late Paleozoic period because they had a much ... , The study, "No giants today: tracheal oxygen supply to ...
... new approach to treating severe nerve pain ?by aiming drugs ... University of Utah scientists who study the venoms of deadly, ... way to treat a chronic and debilitating form of pain ... J. Michael McIntosh, a University of Utah research professor of ...
Cached Biology News:Evolution and the workaround 2Giant insects might reign if only there was more oxygen in the air 2Giant insects might reign if only there was more oxygen in the air 3A new target for painkillers 2A new target for painkillers 3A new target for painkillers 4
(Date:10/20/2014)... 20, 2014 Mapp Biopharmaceutical,s valiant effort ... therapeutic to fight the Ebola outbreak will make ... the production of pharmaceuticals can be, according to ... that while some may be taken aback by ... with industry knowledge are well aware of the ...
(Date:10/20/2014)... 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") ... orders to $5.8 million and provides a good start to Q4.  ... North America and one in the Middle ... at record levels," said Peter Bruijns , President & CEO. ... of Q3 than they have been for any complete year since ...
(Date:10/20/2014)... Oct. 20, 2014 PureTech , a ... big healthcare problems, announced today the closing of ... participation from Invesco Perpetual, a $120 Billion group ... drive PureTech,s existing pipeline forward and to advance ... the scientific creativity to really go for the ...
(Date:10/20/2014)... Local veterinary surgeon, Dr. Tim McCarthy is ... donor stem cells for dogs with osteoarthritis. Dr. McCarthy ... performed clinical stem cell therapy for 7 years. The ... a single injection of donor stem cells into one ... and inflammation in the treated joints. , Candidates ...
Breaking Biology Technology:Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2
... Sigma Life Science, the innovative biological ... SIAL ), announced that its SAGE Labs initiative ... Parkinson,s disease in collaboration with The Michael J. Fox ... SAGEspeed™ model creation process, these off-the-shelf rat models represent ...
... size, antennaswhether in a cell phone or on ... and bandwidth when their size is reduced below ... toward producing antennas by screen-printing, inkjet printing, and ... dipoles and loops," explained Jennifer T. Bernhard, a ...
... 16, 2011 Reportlinker.com announces that a new ... Global Growth Factors ( ... http://www.reportlinker.com/p0397766/Global-Growth-Factors--Blood-And-Tissue--Industry.html This report ... And Tissue) in US$ Million by the following ...
Cached Biology Technology:Sigma® Life Science Launches Suite of Knockout Rats to Model Parkinson's Disease 2Sigma® Life Science Launches Suite of Knockout Rats to Model Parkinson's Disease 33-D printing method advances electrically small antenna design 2Global Growth Factors ( Blood And Tissue ) Industry 2Global Growth Factors ( Blood And Tissue ) Industry 3Global Growth Factors ( Blood And Tissue ) Industry 4Global Growth Factors ( Blood And Tissue ) Industry 5Global Growth Factors ( Blood And Tissue ) Industry 6Global Growth Factors ( Blood And Tissue ) Industry 7Global Growth Factors ( Blood And Tissue ) Industry 8Global Growth Factors ( Blood And Tissue ) Industry 9Global Growth Factors ( Blood And Tissue ) Industry 10Global Growth Factors ( Blood And Tissue ) Industry 11Global Growth Factors ( Blood And Tissue ) Industry 12Global Growth Factors ( Blood And Tissue ) Industry 13Global Growth Factors ( Blood And Tissue ) Industry 14Global Growth Factors ( Blood And Tissue ) Industry 15Global Growth Factors ( Blood And Tissue ) Industry 16
... These 1.5L PYREX trypsinizing ... homogenous tissue samples into cell ... proteins. Heavy beaded neck accepts ... enhance vigorous agitation. • Height ...
... of purified RNA samples., , This product ... aqueous RNA samples that have been pre-purified ... silica, oligo dT etc or other kits. ... necessary components for the stabilization of nanogram ...
Plasmid expressing the LacZ reporter gene....
Puromycin resistance gene (pac), provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
Biology Products: