Navigation Links
Male or female? In flies, some cells can't tell
Date:5/4/2010

pression in the cells of developing flies. The technique attaches a reporter gene to doublesex that makes cells expressing the gene glow green. Tracking doublesex then becomes as easy as watching for green spots in fly embryos, larvae, and adults. With this approach, Baker's group found that during fly development, doublesex switches on and off at different times and in different tissues. As expected, they saw doublesex protein in the genitalia and in other body parts that display differences between males and females. But in body parts where there are not overt differences between males and females, they found that doublesex was expressed only in certain cells and not expressed in many other types of cells. "It's a simple observational study with profound implications," Baker says. This study demonstrates that only a subset of cells is likely to know whether they are male or female. Robinett and her colleagues found that male and female fruit flies are really a mixture of cells that are sex-specific and cells that are sexless. Many of the fly's cells never turn on the doublesex gene. So while, some cells "know" their sex and take on sex-appropriate characteristics during development, those that do not express doublesex remain identical in males and females.

Because doublesex or analogous genes are present in myriad organisms, including humans, this theme may apply to more than fruit flies. "It may be broadly true that males and females are made up of a mosaic of cells that know their sex and cells that don't," Baker says. This could prompt other researchers to check for similar doublesex patterns in other model organisms such as roundworms, zebrafish, and mice. If similar findings emerge, it could shake up the entire notion of sex differences in the animal kingdom. And if the finding applies to humans a big "if" at this point the implications could be even more significant. "If it applies to people, it's certainly going to change our sociological view of
'/>"/>

Contact: Jennifer Michalowski
michalow@hhmi.org
Public Library of Science
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. How do you know whether you are male or female?
2. Broccoli component limits breast cancer stem cells, U-M study finds
3. Scripps Research team provides groundbreaking new understanding of stem cells
4. California funds UCI basic research on stem cells
5. Lensless imaging of whole biological cells with soft X-rays
6. Innovalight Establishes New Record With Silicon Ink Solar Cells
7. Gene silencing may be responsible for induced pluripotent stem cells limitations
8. Production of biofuels could benefit by controlling the types of cells that develop in plants
9. Chloride channels render nerve cells more excitable
10. Scientists sever molecular signals that prolific parasite uses to puppeteer cells
11. Carbon nanotubes boost cancer-fighting cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... Ravi Birla, associate professor of biomedical engineering at ... textbook on tissue engineering and artificial organ development., ... a comprehensive guide to entering into the field ... and professor of biomedical engineering at UH, served ... said that while there are other published books ...
(Date:7/25/2014)... at the University of Adelaide has opened the way for ... powdery mildew. , In Australia, annual barley production is second ... mildew is one of the most important diseases of barley. ... discovered the composition of special growths on the cell walls ... into the leaf. , The research, by the ARC Centre ...
(Date:7/25/2014)... complex congenital central nervous system disease that is ... tubes during the embryonic phase. Many patients have ... and neurocognitive retardation. Such problems decrease the patients, ... at Ankara Physical Medicine and Rehabilitation Education and ... children with SB, using the Pediatric Evaluation of ...
Breaking Biology News(10 mins):University of Houston researcher publishes textbook on tissue engineering 2New hope for powdery mildew resistant barley 2
... a common parasitic infection can vary greatly from person to ... of three strains of the cat-borne parasite Toxoplasma gondii ... it invades. Past research suggests that the parasite, estimated ... exacerbate psychotic symptoms and schizophrenia in genetically predisposed people. ...
... relevant to the effects of a mother’s high-fat ... in her children. An animal study at ... high-fat, high-carbohydrate diet causes oxidative stress—an excess of ... obesity and diabetes. Feeding rats antioxidants before and ...
... researchers from universities across the United States will arrive ... talks with lawmakers and their staffs about how to ... fuel the pursuit for medical breakthroughs in a time ... students participating in Hill Day, a twice-annual event sponsored ...
Cached Biology News:Toxoplasmosis: The strain explains severity of infection 2Antioxidants in pregnancy prevent obesity in animal offspring 2Young scientists to make the case for research funding on Capitol Hill 2Young scientists to make the case for research funding on Capitol Hill 3Young scientists to make the case for research funding on Capitol Hill 4
(Date:7/24/2014)... MENLO PARK, Calif. , July 24, 2014 ... biotechnology company in the emerging field of regenerative ... live webcast of a presentation to investors on ... 1:30 p.m. PDT.  The presentation will include an ... pipeline. To access the webcast, visit http://www.ustream.tv/channel/asterias-biotherapeutics ...
(Date:7/24/2014)... Yung-Eun Sung has announced that they have developed ... which can be applied as high performance electrodes ... is both a group leader at the Center ... (IBS) and a professor at the Seoul National ... regards to the development of relative simplicity, scalablity, ...
(Date:7/24/2014)... to settle into equilibriuma state of unchanging balance ... of non-equilibrium conditions where new possibilities lie. Non-equilibrium ... such as temperature fluctuations, freezing and melting, or ... body temperature, airplanes to fly, and the Earth ... even though these conditions exist naturally and are ...
(Date:7/24/2014)... 2014 Your cell phone may ... lithium-ion battery storage capacity. , New research indicates ... model created at Lawrence Livermore National Laboratory ... how carbon components will perform as electrodes. , ... urgent need for higher-performance batteries. Several key characteristics ...
Breaking Biology Technology:Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4New approach to form non-equilibrium structures 2Getting More Life out of Lithium-ion Batteries 2
... help of 14 satellites currently in orbit and the ... scientists have been able to observe the Earths environment ... the world. The use of remote sensing technology ... the most common and deadly infectious diseases today such ...
... Ind. - Researchers have developed a new modeling ... tool that could help industry perfect lab-on-a-chip technology ... monitoring. , The experimental devices represent a new ... detect specific "target molecules," which will allow the ...
... SHANGHAI, China, Jan. 3 /Xinhua-PRNewswire/ -- WuXi PharmaTech (NYSE:,WX), ... to announce today that it has promoted Mr. Edward ... Officer., Prior to joining WuXi PharmaTech in August ... Operating Officer at Tanox, Inc., a NASDAQ listed,company later ...
Cached Biology Technology:NASA technology helps predict and prevent future pandemic outbreaks 2Model is first to compare performance of 'biosensors' 2Model is first to compare performance of 'biosensors' 3WuXi PharmaTech (NYSE: WX) Promotes Edward Hu to COO 2
Request Info...
Mouse monoclonal [B314.1 (MAC 387)] to Macrophage L1 protein Calprotectin (rating: ****) ( Abpromise for all tested applications)....
Human/Mouse/Rat AMPK beta 1 Affinity Purified Polyclonal Ab...
Immunogen: Tissue / cell preparation. (Murine EHS laminin preparation) Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: