Navigation Links
Male impotence drugs may deserve a second look in women
Date:4/17/2009

f Physiology and a study author. Scientists define female sexual dysfunction as a multifaceted disorder that includes anatomical, psychological, physiological and social-interpersonal aspects.

MCG researchers have shown part of that complexity may be the smooth muscle cells in the internal pudendal arteries of females communicate, agreeing to contract and relax, while male smooth muscle cells make independent decisions to just relax.

They found one other distinction: females were more sensitive to Viagra, or sildenafil, while males were most sensitive to Levitra, or vardenafil.

Previous studies on the effectiveness of these drugs focused on the cavernosal tissue, or penis. The internal pudendal artery actually feeds the penile artery which is buried deep in the penis where numerous caverns enable it to be flaccid when not engorged with blood. Physical stimulation of the area causes the tissue, endothelial cells and nerves to release nitric oxide, a powerful dilator of blood vessels. The system works pretty much the same way in the vagina and clitoris.

"If you have too much constriction or not enough relaxation to allow blood to go through the internal pudendal artery, you are not going to get the net effect of an erection," Dr. Allahdadi says. "That is why we wanted to begin to characterize what was going on in this blood vessel."

Perhaps as importantly, the MCG scientists and others are beginning to believe sexual dysfunction provides an early, or at least visible, clue of vascular disease. Vascular problems, that can result from diabetes, hypertension, high cholesterol and the like, are a major cause of sexual dysfunction in men and women. "You don't feel atherosclerosis but you know darn well if you are not getting an erection," Dr. Webb says. In fact, the MCG scientists are beginning to look at animal models of disease states, such as diabetes, to see what it does to these internal pudendal arteries.

"What
'/>"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Research could lead to new non-antibiotic drugs to counter hospital infections
2. UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs
3. An underwater drugstore?
4. Canadian scientist mines drugs database for new diabetes treatment
5. Scientists mine drugs database for new diabetes treatment
6. Breaking the barrier: Discovery of anti-resistance factors and novel ocean drugs
7. Compounds could be new class of cancer drugs
8. In India: A search for more effective tuberculosis drugs
9. New discovery may lead to new class of allergy drugs
10. Avian flu becoming more resistant to antiviral drugs, says University of Colorado study
11. Study: Excessive use of antiviral drugs could aid deadly flu
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Male impotence drugs may deserve a second look in women
(Date:7/25/2014)... PITTSBURGH -- The routine use of a molecular ... likelihood of performing the correct initial surgery for ... from the University of Pittsburgh Cancer Institute (UPCI), ... the UPMC/UPCI Multidisciplinary Thyroid Center and other diagnostic ... the correct initial surgery by 30 percent, according ...
(Date:7/24/2014)... wildlife loss leads to conflict among people around the ... Society (WCS) Health & Ecosystems: Analysis of Linkages (HEAL) ... approach to tackle global biodiversity decline. , The harvest ... world,s people and provides protein for more than a ... no surprise that today,s unprecedented loss of wildlife, is ...
(Date:7/24/2014)... food or commercial food sale, has been heavily documented ... many species of primates and other mammals. However, ... the species being consumed are birds, particularly large birds ... meat made available for sale but the meat that ... brought to villages for consumption, we noted a significant ...
Breaking Biology News(10 mins):Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3New study draws links between wildlife loss and social conflicts 2
... Cambridge and Boston, MA. Wed. July 4, 2012 One ... after treatment. In the case of many forms of cancer, ... eradicate cancer cells in the lab, but often produce only ... in the field of cancer research has been and remains: ...
... new type of scholarly articles, which are rapidly gaining ... publications that describe data sets and provide an opportunity ... citation and re-use of the published data. Data Papers ... among the international organization Global Biodiversity Information Facilities ...
... coast of North America is reaching the level of the ... by a researcher at the University of British Columbia. ... Bulletin , examined stomach contents of beached northern fulmars on ... Washington and Oregon, U.S.A. "Like the canary in the ...
Cached Biology News:Tumor microenvironment helps skin cancer cells resist drug treatment 2Tumor microenvironment helps skin cancer cells resist drug treatment 3Tumor microenvironment helps skin cancer cells resist drug treatment 4A new type of data papers designed to publish online interactive keys identifying biodiversity 2Seabirds study shows plastic pollution reaching surprising levels off coast of Pacific Northwest 2
(Date:7/24/2014)... -- Research and Markets has announced the ... Instruments Market 2014-2018" report to their offering. ... is the study of the gene and its functions ... functions of proteomes or sets of proteins by using ... the mapping of genes and DNA sequencing to understand ...
(Date:7/24/2014)... 24, 2014  CorMedix Inc. (NYSE MKT: CRMD), ... therapeutic products for the prevention and treatment of ... notice on July 18, 2014 from the NYSE ... the CorMedix plan to regain compliance with continued ... the NYSE-MKT is continuing the Company,s listing and ...
(Date:7/24/2014)... 24, 2014  Neogen Corporation (Nasdaq: NEOG ... its potential revenue from new rodenticide research are premature. ... analysts on July 22, 2014, Neogen,s CEO commented about ... research. "It was my intent Tuesday at ... of a new type of rodenticide, but certainly not ...
(Date:7/24/2014)... Toronto, Canada (PRWEB) July 24, 2014 ... for Optimizing Dose Escalation in First in Human Studies” ... to make better go/no-go decisions. , With increasing R&D ... market, pharmaceutical companies need to maximize the knowledge collected ... go/no-go decisions and improve success in late stage development. ...
Breaking Biology Technology:Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 2CorMedix, Inc. Granted Extension of NYSE-MKT Listing 2CorMedix, Inc. Granted Extension of NYSE-MKT Listing 3Neogen comments on SenesTech 2Best Practices for Optimizing Dose Escalation in First in Human Studies, New Webinar August 6th Hosted by Xtalks 2
... February 2, 2009 Reston, Va. The American ... book, Frontiers of Propulsion Science , that compiles ... novel propulsion concepts as space drives, warp drives, gravity ... and enable human voyages to other star systems. ...
... Pharmaceuticals Inc.,(Nasdaq: TRBN ) today announced that executives ... at two upcoming investor conferences in,February and March: , ... Conference at the Waldorf Astoria, 301 Park,Ave., in New York ... to present at 9 a.m. EST. A replay of the ...
... CAMBRIDGE, Mass., Feb. 3 Abt Associates announced that ... Associate. After a brief orientation to the firm, ... education work in September 2009. Dr. Takai brings ... and management of federal evaluation studies in the field ...
Cached Biology Technology:New book from AIAA explores space drives, warp drives 2Trubion Announces Presentations at Upcoming Investor Conferences 2Dr. Ricky Takai, Expert in Designing and Managing Federal Evaluation Studies in Education, Joins Abt Associates 2
... 1;heading 2;Many mammalian ... experimental situations create ... transfection and other ... ViraPower Lentiviral Expression ...
... Rabbit polyclonal to Kv4.2 Immunogen ... corresponding to amino acids 23-43 of Rat ... with Rat.Expected to cross-react with Human (100% ... immunogen), Rabbit (100% identity with immunogen) and ...
RayBio Human Angiogenesis Antibody Array 2.1 (8 array membranes) with Accessory, detects 23 angiogenic factors (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
... Cryo/CryoPlus Inventory Racks for ... available with cardboard or stainless ... or 5ml cryo vials. ... racks available. Platform risers ...
Biology Products: