Navigation Links
Male impotence drugs may deserve a second look in women
Date:4/17/2009

AUGUSTA, Ga. New studies indicate the three drugs used to treat male impotence also appear to work in females, albeit a little differently, and should give the scientific community pause to take a second look at their potential in the 40 percent of women who report sexual dysfunction, researchers say.

In one of the first studies of the effect of phosphodiesterase Type 5 inhibitors - Viagra, Levitra and Cialis - on the pudendal arteries that supply the penis, vagina and clitoris the blood needed to produce a satisfying sexual experience, Medical College of Georgia researchers showed the drugs relax the artery in male and female rats.

"It shows the drugs need to be investigated more for women and small alterations could make these compounds more effective for women living with these disorders," says Dr. Kyan J. Allahdadi, postdoctoral fellow in physiology at MCG. He's presenting the findings during the 122nd Annual Meeting of the American Physiological Society held in New Orleans April 18-22 as part of the Experimental Biology 2009 scientific conference.

Although there was talk years ago of a pink pill for women to parallel the blue Viagra for men, early clinical trials found essentially no response in women.

MCG researchers decided to look again, first giving a drug to constrict the internal pudendal arteries in male and female rats as they would be in a non-erect state then giving doses of each impotency drug to see the impact. The arteries from male rats displayed a relatively standard concentration-dependent relaxation the more drug they got, the more they relaxed - while in females arteries, there was an initial relaxation then an odd oscillation between relaxation and contraction with subsequent dosing.

While they don't fully understand the swing, the unique female response likely provides more evidence that sexual function is more complex in females, says Dr. R. Clinton Webb, chair of the MCG Department o
'/>"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Research could lead to new non-antibiotic drugs to counter hospital infections
2. UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs
3. An underwater drugstore?
4. Canadian scientist mines drugs database for new diabetes treatment
5. Scientists mine drugs database for new diabetes treatment
6. Breaking the barrier: Discovery of anti-resistance factors and novel ocean drugs
7. Compounds could be new class of cancer drugs
8. In India: A search for more effective tuberculosis drugs
9. New discovery may lead to new class of allergy drugs
10. Avian flu becoming more resistant to antiviral drugs, says University of Colorado study
11. Study: Excessive use of antiviral drugs could aid deadly flu
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Male impotence drugs may deserve a second look in women
(Date:7/27/2014)... might have survived the asteroid strike that wiped them ... later in history, scientists say. , A fresh study ... helped palaeontologists to build a new narrative of the ... They found that in the few million years before ... was experiencing environmental upheaval. This included extensive volcanic activity, ...
(Date:7/27/2014)... have shown the potential for global climate change to ... most part, ignored the interactions between increasing temperature and ... to damage crops. , A new study involving researchers ... significant, suggesting that policymakers need to take both warming ... , The study looked in detail at global production ...
(Date:7/25/2014)... first broad-scale estimate of air pollution removal by trees ... trees are saving more than 850 human lives a ... , While trees, pollution removal equated to an average ... impacts of that improvement are substantial. Researchers valued the ... nearly $7 billion every year in a study published ...
Breaking Biology News(10 mins):Dinosaurs fell victim to perfect storm of events, study shows 2Study: Climate change and air pollution will combine to curb food supplies 2Study: Climate change and air pollution will combine to curb food supplies 3First national study finds trees saving lives, reducing respiratory problems 2
... Colorado at Boulder has been awarded $1 million from ... of Energy to develop rapid solar- thermal chemical reactor ... and algae to synthesis gas. The three-year award ... Weimer of CU-Boulder,s chemical and biological engineering department. ...
... , Iron is vital to human life; for example, ... our blood red and supplies our cells with oxygen. However, ... iron deposits in the brain contribute to certain forms of ... malfunction of the blood transporter transferrin may be to blame. ...
... student in the division of marine geology and geophysics ... Marine and Atmospheric Science, was recently awarded the prestigious ... Geophysical Union (AGU) Fall 2007 Meeting. The prize ... and Future Directives of the Nicoya Peninsula Continuous GPS ...
Cached Biology News:University of Colorado at Boulder awarded $1 million for biofuels research 2Rusty worms in the brain 2Slow slip and slide dynamics 2
(Date:7/28/2014)... COLLEGE STATION, Texas , July 28, 2014   The ... be a 177-key, 4-star boutique hotel in the heart of The ... Texas.  Photo - http://photos.prnewswire.com/prnh/20140725/130455 ... hotel within ATLAS , The ... standard rooms and suites, a sleek restaurant and bar, a wellness ...
(Date:7/26/2014)... NY (PRWEB) July 26, 2014 ... provides key market data on the Canada Endoscopy ... millions of US dollars, volume (in units) and ... - High-End Endoscopy Visualization Systems, Mid-Range Endoscopy Visualization ... Full Report at http://www.marketresearchreports.biz/analysis/213254 . , The ...
(Date:7/25/2014)... each person,s digestive tract. Scientists believe that some of ... infections, but their role in human health is not ... role of these bacteria, a team of researchers led ... in the bacterial populations of two research subjects over ... 25 issue of the journal Genome Biology , ...
(Date:7/25/2014)... New York (PRWEB) July 25, 2014 ... Market Research, "Biological Drugs Market - Global Industry Analysis, ... the global biological drugs market is estimated at USD ... at a CAGR of 10.1% from 2014 to 2020, ... in 2020. , The biological drugs market is witnessing ...
Breaking Biology Technology:Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 2Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 3Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5Monitoring the rise and fall of the microbiome 2Monitoring the rise and fall of the microbiome 3Biological Drugs Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Biological Drugs Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3
... Idenix,Pharmaceuticals, Inc. (Nasdaq: IDIX ), a biopharmaceutical ... the treatment of human viral,and other infectious diseases, announced ... the 43rd Annual Meeting of the European,Association for the ... Milan, Italy,April 23 - 27, 2008. Full abstracts can ...
... Guaranteed Purchase Minimums - Carrington Provides Product Development, Manufacturing ... ... Distribution, IRVING, Texas, Feb. 25 Carrington,Laboratories, Inc. ... agreement with Universal Harvest Corporation of Nevada. Under the,terms of ...
... N.J., Feb. 25 Barr Pharmaceuticals,Inc. (NYSE: ... subsidiary, Duramed,Pharmaceuticals, Inc., has received notification that ... accepted for review its New Drug Application,(NDA) ... mg and ethinyl estradiol tablets 0.01 mg) ...
Cached Biology Technology:Idenix Announces Data Presentations at the 43rd Annual Meeting of the European Association for the Study of the Liver (EASL) 2Idenix Announces Data Presentations at the 43rd Annual Meeting of the European Association for the Study of the Liver (EASL) 3Carrington and Universal Harvest Sign Supply Agreement 2Duramed's Lo SEASONIQUE(R) NDA Accepted for Filing by FDA 2Duramed's Lo SEASONIQUE(R) NDA Accepted for Filing by FDA 3Duramed's Lo SEASONIQUE(R) NDA Accepted for Filing by FDA 4
DNA fragmentation factor & Inhibitor of CAD...
Anti-MT3-MMP Membrane-Type Metalloproteinase-3; propeptide domain; rabbit host...
Anti-CoralHue Dronpa Green Monoclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Chlamydia pneumoniae (TWAR)...
Biology Products: