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Male and female sex cell determination requires lifelong maintenance and protection
Date:5/22/2014

rm production and male fertility, we found that RA also has a dark side. If DMRT1 is not there to act as a guardian of maleness, RA has the potential to activate genes driving male-to-female transdifferentiation," said Zarkower. "This shows cell signaling can transform the identities of the very cells that use it from male to female. We think other cell types may also require similar mechanisms allowing them to use critical signaling molecules without becoming reprogrammed."


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Contact: Caroline Marin
crmarin@umn.edu
612-624-5680
University of Minnesota Academic Health Center
Source:Eurekalert

Page: 1 2

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