Navigation Links
Male and female behavior deconstructed
Date:2/2/2012

Hormones shape our bodies, make us fertile, excite our most basic urges, and as scientists have known for years, they govern the behaviors that separate men from women. But how?

Now a team of scientists at the University of California, San Francisco (UCSF) has uncovered many genes influenced by the male and female sex hormones testosterone and estrogen that, in turn, govern several specific types of male and female behaviors in mice.

The UCSF team selectively turned many of these genes off one by one and found they could manipulate individual behaviors in the mice, like their sex drive, desire to pick fights, or willingness to spend extra time caring for their young.

"It's as if you can deconstruct a social behavior into genetic components," said Nirao Shah, MD, PhD, an associate professor in the Department of Anatomy at UCSF who led the research, which is published in the 2/3/12 issue of the journal Cell. "Each gene regulates a few components of a behavior without affecting other aspects of male and female behavior.

In addition to illuminating the role of genes in male and female behavior, Shah said, the results also have greater implications: If male and female behaviors can be broken down into individual component parts, what other complex behaviors could similarly be deconstructed?

Identifying how genetic differences in our brains account for the differences in our behavior may also be a starting point for understanding how to better address human mental illness and neurodegenerative conditions in which such gender differences exist. For example, autism is four times more common in males than in females.

"Some of the genes we have identified in our study have indeed been implicated in various human disorders that are found in sex-skewed ratios," said Shah. "We won't immediately find all the answers to these disorders based on this research alone, but in the future, it might indeed help to ide
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. The influence of estrogen on female mood changes
2. Female feticide in Canada requires action
3. Fit females make more daughters, mighty males get grandsons
4. Jeanne Baret, botanist and first female circumnavigator, finally commemorated in name of new species
5. Females choose sexier friends to avoid harassment
6. Stronger corn? Take it off steroids, make it all female
7. New research from WALTHAM demonstrates the importance of portion control for maintaining healthy body weight in neutered female kittens
8. Female promiscuity can rescue populations from harmful effects of inbreeding
9. Pitt team finds molecular evidence of brain changes in depressed females
10. Male-female ring finger proportions tied to sex hormones in embryo; may offer health insights
11. Headaches are common in year following traumatic brain injury, especially among females
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Male and female behavior deconstructed
(Date:8/21/2014)... Mller the Fram Strait is a key region in the ... between Greenland and Svalbard warm Atlantic water flows to the ... cold Arctic water masses and sea ice push their way ... portion of the Atlantic water cools here on its way ... of the water caused in this manner drives the global ...
(Date:8/21/2014)... Wednesday, Oct. 18-22, 2014 , WHERE: , ... San Diego, CA 92101 , WHAT: , ... of the latest research in human genetics. Examples ... high-scoring abstracts on rare genetic variants in health ... treatment for sun sensitivity (Saturday, Oct. 18, 5:30-7:30 ...
(Date:8/21/2014)... feeding tube connectors, designed by an international standards process, ... , According to an invited review published in the ... ( NCP ), the official journal of the American ... connectors will greatly reduce the occurrence of misconnection that ... Small-bore connectors, which are used to join medical devices, ...
Breaking Biology News(10 mins):Arctic sea ice influenced force of the Gulf Stream 2Arctic sea ice influenced force of the Gulf Stream 3American Society of Human Genetics 2014 Annual Meeting 2New feeding tube connectors will improve patient safety 2
... review of the principles and management implications of nitrogen ... new monograph Nitrogen in Agricultural Systems . The ... Crop Science Society of America (CSSA), and the Soil ... 30 leading experts to holistically address nitrogen in the ...
... biomedical engineering assistant professor at The University of ... million National Institutes of Health/National Cancer Institute grant ... James Tunnell says the five-year project will include ... Anderson Cancer Center in Houston and the University ...
... In a move that promises to change the economics of ... set of techniques for cleanly converting problematic biofuels waste into ... available online in the journal Metabolic Engineering . The ... new fermentation process that allows E. coli and ...
Cached Biology News:Nitrogen: Nutrient of life 2Research yields pricey chemicals from biodiesel waste 2Research yields pricey chemicals from biodiesel waste 3
(Date:8/21/2014)... 2014 Gallus BioPharmaceuticals , ... and manufacturing organization (CMO) announced today that it ... oncology company focused on the development of innovative ... the anti-prostate specific membrane antigen (PSMA) monoclonal antibody ... Under the agreement the antibody will be produced ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 On Wednesday of ... gel to use Redox Signaling molecules, became available for purchase ... overwhelming. , "The way that RENU 28 works is, if ... slowing down of the rate of cellular renewal within your ... the increasing of that rate of cellular renewal. What RENU ...
(Date:8/20/2014)... inventions licensed to biotechnology firms has revealed early ... these roadblocks, the researchers suggest that better communication ... could lead to faster commercialization down the road. ... made in university laboratories and licensed to biotechnology ... which have a high failure rate. But a ...
(Date:8/20/2014)... For the first time, chemists have succeeded in measuring ... time resolution. The study reveals how vibration of a ... groups. , The study was performed at the ... from the University of Jyvskyl works as a visiting ... in the study. The second team was lead by ...
Breaking Biology Technology:Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 3RENU 28 Skin Care Now Available in Australia and New Zealand 2Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3Seeing a molecule breathe 2
... , SHANGHAI, Nov. 24 /PRNewswire-Asia/ ... (SFDA) has approved the,investigational new drug application (IND) for its ... This IND,approval allows Biolaxy to initiate its first phase I ... disorder characteristic of high blood glucose and poor,metabolism. The complications ...
... Primary efficacy endpoint has been met for ... , QUEBEC CITY, Nov. 24 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. ... biopharmaceutical company focused on endocrine therapy and oncology, today announced ... targeted cytotoxic peptide conjugate, AEZS-108 (formerly AN-152), in patients with ...
... DIEGO, Nov. 24, 2009 Arena Pharmaceuticals, Inc. (Nasdaq: ARNA ... present at the Piper Jaffray 21st Annual Health Care Conference on ... Time) at the New York Palace Hotel in New York City. ... provide an overview of the company, including its clinical development and ...
Cached Biology Technology:Biolaxy Secures IND Approval for Oral Insulin 2AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 2AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 3AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 4Arena Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 2Arena Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 3
... CLS number is a new ... match Cornings product number. If ... order under the old Sigma-Aldrich ... service for assistance. Mfr ...
A cost-effective serum for general cell growth requirements. All serum is collected from calves aged 10 days old or less....
... This CLS number is ... to easily match Cornings product ... yet, please order under the ... contact customer service for assistance. ...
... cell culture scale-up, these culture chambers produce ... 10 9 range and are useful ... flasks. • High mechanical • strength and ... to shipping • Certified nonpyrogenic and sterilized ...
Biology Products: